Immuno9 Flashcards
Hypersensitivity Disorders
Examples of Type I hypersensitivity.
Anaphylaxis (bee sting, food/drug allergies)
Allergic and Atopic disorders (rhinits, hay fever, eczema, asthma)
Examples of Type II hypersensitivity.
“Disease tends to be specific to tissue or site where Ag is found”
- Autoimmune hemolytic anemia
- Pernicious anemia
- Idiopathic thrombocytopenic purpura
- Erythroblastosis fetalis
- Acute hemolytic transfusion reactions
- Rheumatic fever
- Goodpasture’s syndrome
- Bullous pemphigoid
- Pemphigus vulgaris
Examples of Type III hypersensitivity.
“Can be associated with vasculitis and Systemic manifestations”
- SLE
- Polyarteritis nodasa
- Poststreptococcal glomerulonephritis
- Serum sickness
- Arthus reaction (swelling and inflammation following tetanus vaccine)
Examples of Type IV hypersensitivity.
“Response is delayed and does NOT involve antibodies”
- Multiple sclerosis
- Guillain-Barre syndrome
- Graft-vs-Host disease
- PPD (test for TB)
- Contact dermatitis (poison ivy, nickel allergy)
SLE
Type III
Pernicious anemia
Type II
Multiple sclerosis
Type IV
Polyarteritis nodasa
Type III
Idiopathic thrombocytopenic purpura
Type II
Serum sickness
Type III
Goodpasture’s syndrome
Type II
Contact dermatitis (poison ivy, nickel allergy)
Type IV
Autoimmune hemolytic anemia
Type II
Bullous pemphigoid
Type II
Guillain-Barre syndrome
Type IV
