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Pharm > Psych Pharm > Flashcards

Psych Pharm Flashcards

1
Q

Preferred drug: EtOH withdrawal?

A

Benzos

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2
Q

Preferred drug: anxiety

A

SSRI, SNRIs, buspirone

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3
Q

Preferred drug: ADHD

A

Methylphenidate, amphetamine

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4
Q

Preferred drug: bipolar

A

lithium, valproate, carbamazepine

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5
Q

Preferred drug: bulemia

A

SSRI

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6
Q

Preferred drug: depression

A

SSRI, SNRI, TCA, buspirone

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7
Q

Preferred drug: depression with insomnia

A

mirtazapine

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8
Q

Preferred drug: OCD

A

SSRI, clomipramine

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9
Q

Preferred drug: Panic disorder

A

SSRIs, venlafaxine, benzos

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10
Q

Preferred drug: PTSD

A

SSRIs

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11
Q

Preferred drug: social phobias?

A

SSRIs

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12
Q

Preferred drug: tourette’s

A

haloperidol, risperidone

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13
Q

Drugs that increase catecholamines at synaptic cleft, esp DA and NE. Use?

A

Methylphenidate, dextroamphetamine, methamphetamine. ADHD, narcolepsy, appetite control

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14
Q

Pt wants to control appetite. Can give?

A

Methylphenidate, -amphetamines

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15
Q

MoA of antipsychotics?

A

Haloperidol and -azines. Block D2 receptors, increasing cAMP.

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16
Q

Side effects of high potency antipsychotics?

A

Trifluoperazine, Fluphenazine, Haloperidol (Try to Fly High). Extrapyramidal symptoms Dyskinesias etc)

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17
Q

Side effects of low potenncy antipsychotics?

A

Chlorpromazine, thioridazine. (Cheating theives are low). Anticholinergic, antihistamine, a1-block

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18
Q

Antiphychotic treat what type of schizophrenia symptoms?

A

postive

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19
Q

Side effect in female schizophrenic treated with antipsychotic?

A

Galactorrhea (decreased DA -> more prolactin)

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20
Q

Pt comes in with a slowly developing rigidity, myoglobinema, and fever, encephalopathy. Cause? Treat with?

A

Neuroletic malignant syndrome. Dantrolene and D2 ags (bromocriptine)

NMS: FEVER
Fever, encephalopathy, unstable vitals, elevated enzymes, rigidity of muscles

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21
Q

Pt with well controlled, long term phychosis comes in with stereotypic oral-facial movements. From what drug?

A

tardive dyskinesia from high potency antipsychotics.

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22
Q

Evolution of EPS side effects?

A

4 hr dystonia
4 day akathisia (restlessness)
4 wk bradykinesia
4 mo tardive dyskinesia

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23
Q

Atypical antipsychotics

A

Olanzapine, clozapine, quetiapine, risperidone, aripiprazole, ziprasidone
(Its atypical for OLd CLOSets, to QUIETly RISPER from A to Z)

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24
Q

Corneal deposits, side effect of what antipsychotic? Retinal deposits?

A

Chloropromazine, Thioridazine

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25
Q

Drugs that have various effects on 5HT2, DA, a-ad, and H1 recptors - used for?

A

Schizo (both + and - symptoms)

Bipolar, OCD, anxiety, depression, mania

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26
Q

Atypical that may cause weight gain?

A

Clozapine and olanzapine

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27
Q

Atypical that needs to be monitored weekly?

A

Clozapine - agranulocytosis.

Watch clozapine closely

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28
Q

Atypical that may prolong QT?

A

Ziprasidone

29
Q

Psych drug used for SIADH

A

Lithium

30
Q

Side effects of Lithium?

A 
LMNOP
Lithium
Movement (tremor)
Nephrogenic diabetes insipidus
HypOthyroidism 
Pregnancy Problems
31
Q

Pregnant women takes lithium. risk of

A

Ebstein’s anomaly (tricuspid problem( and malformation of great vessels

32
Q

Problem with lithium

A

narrow therapeutic window

33
Q

Li excreted by? (most is resorbed where?)

A

kidney; PCT with Na

34
Q

Pt comes in with heart block and polyuria - what psych drug is she on?

A

Li

35
Q

MoA of drug for GAD that does not interact with alcohol

A

Buspirone. Stimulates 5HT1a.

Anxiously waiting for the BUS

36
Q

SSRIs?

A

Fluoxetine, paroxetine, sertraline, citalopram

Flashbacks paralyze senior citizens

37
Q

Pt comes in complaining SSRI isn’t working. Say?

A

wait 8 weeks

38
Q

Pt comes in with rapid onset fever, confusion, myoclonus and heart problems. Drugs that caused it? MoA of drug that can Tx?

A

Serotonin syndrome (MAOIs, SSRIs, SNRIs), Tx with cyproheptadine, 5HT2 antag

39
Q

depressed Pt had too many side effects on drug. Replaced with another drug that alleviated most effect but caused anorgasmia.

A

SSRI, fewer side effects than TCAs, but anorgasma

40
Q

SNRIs

A

Venlafaxine and duloxetine

41
Q

Used in panic disorders and GAD?

A

Venlafaxine

42
Q

psych drug used for diabetic perpheral neuropathy?

A

Duloxetine

43
Q

SNRI with greater effect on NE?

A

Duloxetine

44
Q

Pt comes in with increased BP, nausea and sedation. Side effect of?

A

SNRIs

45
Q

TCA - suffixes and exceptions?

A

-iptyline and -ipramine

except doxepin and amoxapine

46
Q

TCA for bedwetting

A

imipramine

47
Q

TCA for OCD

A

clomipramine

48
Q

Pt with fibromyalgia comes in with postural hypotension, urinary retention and dry mouth. side effect of?

A

TCAs

49
Q

TCA side effects?

A

Convulsions, Coma, Cardiotoxicity

50
Q

Pt given amitriptyline and has confusion and hallucinations. Try this instead

A

2ndary TCA like nortriptyline have fewer anticholinergic side effects than tertiary TCAs like amitriptyline

51
Q

TCA that is less sedating and has lower seizure threshold?

A

Desipramine

52
Q

PT with arrhythmia, and convulsions. Goes into coma. Treat arrythmia with?

A

Side effects of TCAs. Tx with HCO3.

53
Q

MAO-Is?

A

Tranylcypromine, Phenelzine, Isocarboxazid, Selegiline

MAO Takes Pride In Shanghai

54
Q

Selective MAO-B Inhibitor?

A

Selegiline

55
Q

MAOIs vs SNRIs, vs TCAs,

A

MAOIs - block degradation of NE,5HT,DA
SNRI - block reuptake of NE,5HT
TCAs - block reuptake of NE, NE

56
Q

tx for hypochondriasis?

A

MAO-Is

57
Q

Tx for Atypical depression?

A

MAO-Is

58
Q

If on this drug, cannot eat this food because it will cause this

A

MAO-I don’t eat wine/cheese. Increased tyramine will cause hypertensive crisis

59
Q

Contraindications of MAO-Is?

A

TCAs, St. John’s wart, meperidine, dextromethorphan

60
Q

Antidepressant used for smoking sensation affects these NTs?

A

Bupropion increases NE and DA by unknown ways

61
Q

Drug causes seizures in bulimic and anorexic pts?

A

Bupropion

62
Q

atypical Antidepressant Drug with no sexual side effects?

A

Bupropion

63
Q

MoA of Antidepressant that is also used for anorexics to gain weight?

A

Mirtazapine.

1) a2 antag (increases NE and 5HT)
2) antag of 5HT2 and 5HT3

64
Q

Drug used as an antidepressant and sleep aid?

A

Mirtazapine

65
Q

MoA of Antidepressant that can cause sedation and orthostatic hypotension?

A

Maprotiline. blocks NE reuptake

66
Q

Used primarily for insomnia but is an antidepressant at high doses?

A

Trazodone

67
Q

Side effect of trazodone?

A

priapism (trazobone), postural hypotension

68
Q

Pt gets dystonia from neuroleptic. Treat with?

A

Anticholinergic (benztropine)

Pharm (15 decks)

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