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Pharm > Renal Pharm > Flashcards

Renal Pharm Flashcards

1
Q

Drugs that act in the PCT?

A

Mannitol and Acetazolamide

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2
Q

Pt with increased ICP and IOP? Diuretic that can be given?

A

Mannitol

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3
Q

pulmonary edema and dehydration are Toxicities of what diuretic?

A

Mannitol

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4
Q

Pt with CHF. Do not give this diuretic?

A

Mannitol

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5
Q

Pt with anuria. Contraindicated diuretic?

A

Mannitol

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6
Q

Drug that causes self-limited NaHCO3 diuresis. Uses? cause what type of acid-base disturbance?

A

Acetazolamide. Used for Glaucoma, metabolic alkylosis, altitude sickness, pseudotumor cerebri. Hyperchloremic Acidosis

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7
Q

Pt treated for altitude sickness. Comes in with NH3 toxicity. Drug?

A

Acetazolamide

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8
Q

Pt treated for pseudotumor cerebri. Comes in with paresthesias. Other toxicities

A

Acetazolamide. HyperCl Metabolic acidosis ammonia toxicity, sulfa allergy

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9
Q

Drugs that work in TAL?

A

Loop diuretics and Ethacrynic acid

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10
Q

Drug that abolishes hypertonicity of medulla, preventing concentration of urine. Can cause excretion of what electrolytes?

A

Loop diuretics (furosemide). Excretion of Ca and K

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11
Q

Pt on that drug that stimulates PGE release to vasodilate AA. Toxicities?

A 
Furosemide - OH DANG
Ototoxicity
HypoK
Dehydration
Allergy
Nephritis
Gout
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12
Q

Pt on this drug for diuresis in loop of henle has sulfa allergy. Derived from? Never use it to treat?

A

Ethacrynic acid. Phenoxyacetic acid. Can cause hyperuricemia, never use to treat gout

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13
Q

Drug that should never be given with pt with gout?

A

Ethacrynic acid (can cause hyperuricemia)

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14
Q

Diuretic that may cause hyperCa, may also cause?

A

HCT. Hyper-glycemia, -lipidemia, -uricemia, -calcemia

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15
Q

This diuretic can be used for nephrogeneic diabetes insipidus?

A

HCT

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16
Q

This diuretic can be paradoxically used for idiopathic hyperCa?

A

HCT

17
Q

Diuretic for CHF?

A

HCT or K-sparing

18
Q

K sparing diuretics?

A

The K STAys

Spirolactone, Amiloride, Triamterene and eplerenone

19
Q

Diuretics that can cause gynecomastia, also block?

A

Spirolactone and eplerenone. Block ALDO

20
Q

Diuretics that may cause acidosis?

A

Carbonic Anhydrase inhibitors (decrease HCO3)

K-sparing (decreases K/H secretion)

21
Q

MoAs Diuretics that may cause Alkalemia?

A

Loop diuretics and thiazides

1) increase HCO3 while volume contracting
2) K loss leads to H entering cells
3) In low K states, H is excreted in exchange for Na

22
Q

Ca increased with this diuretic? Decreased with this?

A

thiazides; loop

23
Q

Diuretic that can prevent unfavorable heart remodeling as a result of chronic hypertension?

A

ACE-Is

24
Q

ACE-Is - side effects?

A 
CATCHH
Cough
Angioedema
Teratogen
Creatinine increase (down GFR)
HyperK
Hypotension
25
Q

Avoid using this diuretic if patient has bilteral renal artery stenosis?

A

ACE-Is

Pharm (15 decks)

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