rhinosinusitis Flashcards

1
Q

when evaluating a pt with sinusitis-like symptoms, what will you expect if they start with a runny nose? sore throat? if there is presence of exudate?

A

runny nose: sinusitis
sore throat: strep
exudate: bacterial over viral

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2
Q

what is the likely cause of rhinosinusitis?

A

viral: makes up 90-99% of sinusitis cases

bacterial 0.5-2% …except in children admitted to ER for high fever.. liklihood for either is about the same

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3
Q

which clinical presentations qualify pts to be evaluated for AVRS vs ABRS (one of three)?

A
  1. PERSISTENT S&S of rhinosinusitis for >10 days, no improvement
  2. SEVERE symp (high fever, purulent nasal discharge, or facial pain): 3-4 consecutive days
  3. WORSENING symp. or “double-sickening” (better then worse again) >3-4 days.
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4
Q

what do we use for empiric treatment of ABRS in children and adults?

A

Amox-clav (augmentin)

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5
Q

what 5 pt populations are at risk for antibiotic resistance?

A
<2 or >65, daycare
prior ABX in past month
prior hospitalization in the past 5 days 
comorbidities
immunocomprimised
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6
Q

what symptomatic management will you use for pts with AVRS or ABRS? those at risk for Abx resistance? those not at risk?

A

at risk: 2nd-line antimicrobial therapy

no risk: 1st line antimicrobial therapy

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7
Q

for both at-risk and not at risk pts what do you do if they are improving on treatment in 3-5 days?

A

at-risk: complete 7-10 days of abx

not at-risk: complete 5-7 days of abx

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8
Q

what to do if pt (at-risk or not at-risk) if worsening or no improvement in 3-5 days?
if improvement?
if still no improvement in 3-5 days after?

A

broaden coverage or switch to another abx class
improvement:
no-risk: finish 5-7 days
at-risk: finish 7-10 days

if still not improving 3-5 days, refer to specialist:

  • sinus CT or MRI
  • direct sinus puncture culture/sinus tap (GOLD STANDARD) or middle meatal cultures
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9
Q

by definition a URI (cold) is bacterial or viral?

A

viral

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10
Q

bacterial sinusitis: what are the two causes?

A

community acquired: S. PNEUMO, H. FLU, M. CATARRHALIS & Strep A, Staph (caps= 3 most common)
nosocomial (hospital): nasogastric tubes, staph/pseudomonas/other gram neg.

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11
Q

what does “high value care” mean?

A

that the test is WORTH doing, not necessarily that it is cheap

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12
Q

what three signs/symptoms distinguish bacterial from viral?

A
foul odor
dental pain (maxillary)
ansomnia (can't smell)
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13
Q

what are the 4 red flags for ABRS?

A
  1. abnormal vision, esp double vision
  2. periorbital edema
  3. change in mental status (could be brain infection)
  4. very high fever (esp. bad if adult)
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14
Q

ABRS PE: vital signs, eyes, nose, throat, face, neck, chest

A

Vital signs – may be febrile, otherwise wnl
Eyes – possible clear D/C, otherwise wnl
Nose – turbinates swollen, possible purulent D/C visible
Throat – likely inflamed, absence of tonsillar exudates, possible foul breath, possible posterior drainage, possible posterior pharyngeal cobblestoning if chronic drainage
Face – tenderness to palpation/percussion of maxillary and/or frontal sinuses
Neck – possible anterior cervical lymphadenopathy
Chest – normal exam, but cough possible

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15
Q

what is cobble-stoning in the throat? what is a sign of ?

A

clumps of hypertrophic lymphoid tissue @ posterior pharynx

chronic inflammation, significant PND

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16
Q

3 tests for ABRS

A
  1. transillumination: shine light through sinus into the mouth, only significant if asymm (detects if sinus is full)
  2. sinus puncture/sinus tap & aspirate (GOLD STANDARD) but only done in clinical research
  3. radiology: CT for recurrent ABRS (maybe a structural cause)
17
Q

treatment for ABRS

A

cover big 3 pathogens (M. Catt, H. Flu, S. Pneumo)

  1. amox-clav (augmentin
  2. if PCN allergic….3rd gen cephalosporins
  3. respiratory fluoroQs (levofloxacin) ONLY if no other good alternative (bad ADRs)
    * 5-7 txt for adults, 10-14 for kids, longer txt for chronic or recurrent
    * once symptoms subside, take for 2 more days the stop
18
Q

what should always be included in Ddx of sinusitis?

A

paranasal sinus cancer (persistent pain, epistaxis, prolonged clinical course)

19
Q

AVRS vs ABRS: S&S?

A

same S&S, viral is less severe (aka URI)
almost never have a fever
resolves on its own 5-7 days (shorter than ABRS)

20
Q

Hadley’s txt of garden variety sinus infections

A
  1. bacterial = augmentin
  2. afrin: 2 sprays BID for 4 days
  3. anti-inflamm meds for comfort (ibuprofen or naproxen)
  4. guafenesin (mucinex/robitussin) & fluids
  5. saline rinse
  6. allergic trigger? nasal steroid spray w/ afrin (maybe chronic antiHistamine?)
  7. pt education
21
Q

AVRS txt: what events do you want to block? what 5 meds do you want to use?

A
block inflamm events: nasal fluid production &amp; inflamm.
meds:
antihistamines
NSAIDS
cough suppressant
decongestants
mucolytics
22
Q

why do you want to avoid 1st gen antihistamines for ABRS:?

A

they thicken secretions

*while expectorants (guafenisin aka mucinex) will thin them

23
Q

what is chronic sinusitis?

A

> 12 wks of S&S, issues w/ mucociliary clearance

  • mucopurulent drainage
  • nasal obstruction
  • facial pain
  • purulent mucus/edema in meatus/ethmoid OR polyps OR image showing inflamm of sinuses
24
Q

what is recurrent sinusitis?

A

4+ episodes a year with absent symptoms between episodes

25
Q

what is included in the PE for chronic sinusitis?

A
  1. nasal exam w/ speculum & endoscope (purulent drainage, polyps, septal deviation, turbinate hypertrophy/edema)
  2. sinus palpation/percussion for tenderness
  3. ears for TM fluid, neck for LAD, throat for PND, ocular for oculomotor involvement, lung for lower RI/asthma
26
Q

txt for chronic sinusitis? if it is bacterial-chronic?

A

no gold standard, refer to ENT
(maybe intranasal steroids, decong., mucolytics)
true chronic is rare
1 month abx if bacterial-chronic

27
Q

what to look at for general Dx of allergic rhinosinusitis

A

look at history: (perennial (likely from house) vs seasonal(hay fever))
chronicity: maybe recurrent ABRS/AVRS (3-4 infections/year
S&S: clear rhinorrhea with allergy symp. (sneezy, itchy)
*clear fluid behind TM

28
Q

3 giveaway signs of allergic rhinosinusitis

A
  1. allergic salute
  2. crease in nose (from allergic salute)
  3. allergic shiners
29
Q

allergies are closely tied to what other illness?

A

asthma

30
Q

3 types of therapy for allergies Rh?

A
  1. avoidance
  2. drug: inhibit action of released mediators, reversal of vascular and inflamm response
  3. immunotherapy: repeated long-term injection of allergen to blunt rxn
31
Q

what meds are used for drug therapy of allergic rhinosinutisis?

A

antiH1
anticholinergic (atrovent spray)
nasal steroid spray
mast cell stabilizers (inhibit degradation)
leukotriene antagonists (inhibit vascular permeability & inflamm)

32
Q

what is vasomotor rhinosinusitis?

A

trigger by smells, stress, and substances (smoke, cold air)

= sneezing and runny nose, congestion (parasymp overactivity of nasopharynx)

33
Q

txt for vasomotor rhinosinusitis?

A

atrovent (aka ipratropium) spray PRN
*don’t use nasal steroid spray
* don’t use decongestants
maintenance med so you don’t want to use steroids or decongestants all the time

34
Q

pts who are sensitive to vasomotos Rh also tend to get what?

A

migraines

35
Q

nasal polyps: what are they? can they be removed?

A

inflamed outgrowths of nasal mucosa

-may be removed but most return

36
Q

what are nasal polyps assosciated with?

A
asthma
chronic sinus infections
cystic fibrosis
allergic rhinitis
hyposmia (reduced ability to smell)
37
Q

what is samter’s triad?

A

type 1 hypersens.

  1. rhino-sinusitis
  2. asthma and aspirin sensitivity
  3. nasal polyps
38
Q

symptoms of exposure to aspirin or NSAIDS for those with samter’s triad? txt for this?

A
flushing of head/neck/chest
bronchoconstriction
wheezing
cyanosis
N/V/D
txt: bronchodilators