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Biochemistry > Amino Acids > Flashcards

Amino Acids Flashcards

1
Q

Tryptophan

A

AROMATIC SIDE CHAIN

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2
Q

Methionine

A

Non-polar

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3
Q

Aspartic Acid

A

Derived from Asparagine

Negatively charged (acidic) side chains at 7.4 pH

Aspartate is the deprotonated form (minus the H in OH) = O-

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4
Q

Threonine

A

has OH group can participate in HB

Polar

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5
Q

Tyrosine

A

Aromatic

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6
Q

Glycine

A

* Only AA that is Achiral

Non-polar

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7
Q

Isoleucine

A

Non-polar

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8
Q

Lysine

A

Positively charged

has a terminal primary amino group

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9
Q

Proline

A

Non-polar

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10
Q

Asparagine

A

Polar

Amid Side chain

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11
Q

Phenylalanine

A

Aromatic

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12
Q

Glutamine

A

Polar

Amid Side chain

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13
Q
A
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14
Q

How much does an AA weight

A

110 Da

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15
Q

Cysteine

A

Only AA with (R) configuration

Has a thiol (-SH)

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16
Q

Histidine

A

Positively charged

17
Q

Valine

A

Non-polar

18
Q

Amphoteric Species

A

they can either accept or donate a proton

AA can donate from the carboxylic group or receive in the amino group

19
Q

Glutamic Acid

A

Derived from Glutamine

Negatively charged (acidic) side chains at 7.4 pH

Glutamate is the deprotonated form (minus the H in OH) = O-

20
Q

Leucine

A

Non-polar

21
Q

Serine

A

has OH group can participate in HB

Polar

22
Q

Alanine

A

Non-polar

23
Q

Arginine

A

Positively charged (basic)

24
Q

How many pKa’s in amino acids

A

AA with ionizable side chains have 3

K, Y, R, C, H, E, D

Lysine, Tyrosine, Argenine, Cystine, Histine, Glutamic Acid, Aspartate

25
Q

Are Peptide Bonds thermodynamically and kinetically stable or unstable?

A

thermodynamically: Stable
kinetically: unstable

26
Q

What does the pKa mean?

if pH is lower than pKa what does that indicate?

A

the pKa of a group is when half of its molecules are half deprotonated

if pH lower than pKa, means that majority are protonated

Biochemistry (11 decks)

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