Drugs Flashcards
1
Q
What are PPIs?
A
Proton Pump Inhibitors
2
Q
What are PPIs used to treat?
A
Acid reflux, peptic ulcers
3
Q
What effect do PPIs have on the body?
A
Reduce the amount of acid produced by parietal cells
4
Q
How do PPIs work?
A
irreversibly blocking the H+/K+ ATPase enzyme or the gastric proton pump
5
Q
What effect can prolonged use of PPIs have?
A
Can result in high levels of gastrin when you stop taking them meaning the patient may get some reflux symptoms.
6
Q
what are H2 receptor antagonists?
A
They block H2 receptors
