Test 2 Questions Flashcards
Allergic Rhinitis…tell me about allergens and how they trigger histamine release
histamine in mast cells
what triggers histamine release?
forein substance activate WBC produce IGE , repeat exposure triger activation must cells and release histamin
can you have allergic reaction with first exposure to allergen?
no, Requires repeat exposure to allergen
What is first line for allergic rhinitis?
intranasal glucocorticoids
are intranasal glucocorticoids prn or daily?
daily
1st gen/2nd gen antihistamines
1st-sedation
1st- potential for anticholinergic effects
what are anticholinergic effects?
cant pee, cant see, cant shit
oral and intranasal decongestants…how do they work? Mechanism of action?
Use alpha1 adrenergic receptors (nervous system) to cause vasoconstriction:
Drugs like Phenylephrine, pseudoephedrine
systemic oral decongestants…what population should we be cautious in prescribing?
HTN
CVD
Intranasal decongestnts like Afrin…provide me with some education points for your patient?
rebound reaction, cannot use more than 5 day
Drugs for cough…talk to me about benzonatate (Tessalon Perles)…how do they work?
They are derivative of local aneshetic…numbs (decreases sensitivity) to stretch receptors that promote cough
benzonatate patient education
cant give to kids
must take whole, no sucking chewing, or dissolving med in mouth
what do we treat the inflammation with?
inhaled glucocorticoid
how do we treat bronchoconstriction?
bronchodilators
ICS therapy is critical part of asthma treatment. Tell me about these drugs…how do they work?
Suppress inflammation