COPD Flashcards
What is COPD
Chronic bronchitis
Emphysema
-productive cough more than 3 months of year for 2 consecutive years-
Does COPD cause clubbing
NO
What is the scale used for impact of COPD?
MRC Dyspnoea scale
Grade 1 – Breathless on strenuous exercise
Grade 2 – Breathless on walking up hill
Grade 3 – Breathless that slows walking on the flat
Grade 4 – Stop to catch their breath after walking 100 meters on the flat
Grade 5 – Unable to leave the house due to breathlessness
What does spirometry show?
Obstructive
FEV1/FVC ratio of <0.7
Non reversible
How is severity of COPD graded?
3-5-8- fibonacci (add on prev number
With FEV1 Stage 1: FEV1 >80% of predicted Stage 2: FEV1 50-79% of predicted Stage 3: FEV1 30-49% of predicted Stage 4: FEV1 <30% of predicted
What other investigations should be done in COPD?
Chest xray to exclude other pathology such as lung cancer.
Full blood count for polycythaemia or anaemia. Polycythaemia (raised haemoglobin) is a response to chronic hypoxia.
Body mass index (BMI) as a baseline to later assess weight loss (e.g. cancer or severe COPD) or weight gain (e.g. steroids).
Sputum culture to assess for chronic infections such as pseudomonas.
ECG and echocardiogram to assess heart function.
CT thorax for alternative diagnoses such as fibrosis, cancer or bronchiectasis.
Serum alpha-1 antitrypsin to look for alpha-1 antitrypsin deficiency. Deficiency leads to early onset and more severe disease.
Transfer factor for carbon monoxide (TLCO) is decreased in COPD. It can give an indication about the severity of the disease and may be increased in other conditions such as asthma.
What is non medical management of COPD?
Stop smoking
Pulmonary rehab training
Pneumococcal and flu vaccine
What is medical management of COPD?
- SABA/SAMA (ipatropium)
- If no asthma/steroid responsiveness- LABA and LAMA combination inhaler
- If positive asthma or steroid response then LABA and ICS “Fostair”, then stepped up to LABA LABA and ICS triple therapy
3 If severe nebs/oral theophylline/ carbocysteine/prophylactic azithro/O2 at home
What are indications for home O2?
Chronic hypoxia
Polycythaemia
Cyanosis
Heart failure secondary to cor pulmonae
What is seen on an ABG for COPD?
Acidosis if CO2 retention
Raised bicarb indicated they chronically retain CO2- if still acidotic is acute on chrnoic
What is ABG for type 1 resp failure
Normal pCO2 with low O2
only 1 affected
Raised CO2 and low PO2
Type 2
2 affected
What are issues with home O2?
Excessive O2 can depress resp drive slowing breathing and effort and leading to increased CO2 retention. If already retaining CO2 needs careful monitoring with ABGs and O2 sats
What masks are used in COPD O2
Venturi so that % controlled
What Sats aimed for in home O2?
88-92% if retaining
If not retaining >94%