Vitamin B9 (Folic Acid)

Question 1

Deficiency of folic acid occurs in?

Answer 1

Pregnant women, alcoholiscs

Question 2

______________ converts folic acid into DHF and DHF into THF.

Answer 2

DHF Reductase

Question 3

Methotrexate ___________ (inhibits/stimulates) DHF reductase

Answer 3

inhibits

Question 4

N5 methyl THF helps in __________ synthesis from homocysteine

Answer 4

Methionine

Question 5

N5, N10 methylene helps in ____________ synthesis and _________ synthesis from glycine.

Answer 5

Thymidine monophosphate

serine

Question 6

N10 formyl THF helps in __________(purine/pyrimidine) nucleotide synthesis

Answer 6

purine

Question 7

Deficiency of folic acid results in ____________ anemia

Answer 7

macrocytic (megaloblastic)

Question 8

Deficiency of folic acid in pregnant woman can result in ______________

Answer 8

Neural tube defects

Question 9

NTDs at day 23 will result in ______________

Answer 9

Anencephaly

Question 10

NTDs at day 26 will lead to _______________

Answer 10

Spina Bifida

Question 11

______ mg/day folic acid should be taken

Answer 11

0.4 mg/day