CHAPTER 17 Flashcards

1
Q

cognitive systems

-Cognitive cerebral functions require a functioning _____ (RAS)

A

reticular activating system

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2
Q

the reticular formation

  • the reticular formation extends through the central core of the _____, _____, and _____
  • it is an intricate system composed of _____ in what is otherwise _____
A
medulla oblongata 
pons
midbrain
loosely clustered neurons 
white matter
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3
Q

Direct destruction of the reticulating activation system (RAS)

  • _____ disorders produce a decline in _____ through a direct destruction of the RAS and its pathways.
  • The most common cause of direct destruction is _____, but _____, _____, _____, _____, and _____ injury also may cause brainstem destruction by _____ compression.
A
Infratentorial 
arousal
cerebrovascular disease
demyelinating diseases
neoplasms
granulomas
abscesses
head
tissue
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4
Q

alterations in arousal
pattern of breathing
-_____: Lower brainstem centers regulate breathing pattern
-_____: Abnormal rhythm of breathing with alternating periods of hyperventilation and apnea

A

Posthyperventilation apnea

Cheyne-Stokes respirations

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5
Q

Posthyperventilation apnea (PHVA)

  • With normal breathing, a neural center in the forebrain (_____) produces a _____ breathing pattern. When consciousness decreases, _____ regulate the breathing pattern by responding only to changes in _____ levels.
  • This irregular breathing pattern is called _____
  • Rhythmic breathing returns when the carbon dioxide PCO2 level returns to _____.
A
cerebrum
rhythmic
lower brainstem centers
PaCO2
PHVA
normal
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6
Q

Cheyne-Stokes

-Cheyne-Stokes respiration is an abnormal rhythm of breathing (_____ breathing) that alternates between _____ and _____.

A

periodic
hyperventilation
apnea

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7
Q
Alterations in Arousal
motor responses
-\_\_\_\_\_, \_\_\_\_\_, and \_\_\_\_\_
Involve the medulla.
Vomiting without nausea indicates the direct involvement of the \_\_\_\_\_ mechanism (or \_\_\_\_\_ obstruction).

-Vomiting, yawning, and hiccups are complex reflexlike _____ responses that are integrated by _____ mechanisms in the _____ brainstem. Vomiting often accompanies CNS injuries that involve the _____

A
Vomiting
yawning
hiccupping
central neural
pyloric
motor
neural
lower
vestibular nuclei
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8
Q

Brain Death (Total Brain Death)
Brain death criteria:
-Completion of all appropriate, _____
-_____ (absence of motor and reflex responses)
0No spontaneous _____ (apnea)
-No _____ function
-Isoelectric (flat) electroencephalography (EEG) for _____ hours.

A
therapeutic procedures
Unresponsive coma
respirations
brainstem
6 to 12
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9
Q

cerebral death
survivors of cerebral death
-Emerge into a _____

diagnostic criteria for a vegetative state
-Include the return of professed vegetative (_____) functions

  • _____ cycles
  • normalization of _____ and _____ system functions
A
vegetative state
autonomic
Sleep-wake
respiratory
digesive
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10
Q

delirium
Clinical manifestations
-Autonomic nervous system overactivity
-Typical development of over _____ days, most commonly in _____ units, _____, or during withdrawal from _____ (e.g., alcohol, narcotic agents)

A

2 to 3
critical care
postsurgically
central nervous system (CNS) depressants

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11
Q

dementia clinical manifestations

  • _____
  • _____
  • _____
A

memory
speech
decision making

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12
Q

alzheimers disease
Pathophysiology
-No known cause
-_____ plaques, _____ tangles, as well as _____ and _____ losses in the brain, characterize Alzheimer disease.

A

Amyloid
neurofibrillary
neuronal
synaptic

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13
Q

seizure disorders

  • Seizure: Is a sudden, _____ alteration of brain function caused by an abrupt _____, disorderly discharge of _____.
  • Diseases and conditions associated with seizure disorders
  • -Although the _____ may be supplemented with the remaining options, it remains the pivotal tool for establishing the cause of a seizure disorder.
A

transient
explosive
cerebral neurons
history

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14
Q

The most critical aspect in correctly diagnosing a seizure disorder and establishing its cause is _____

A

health history

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15
Q

seizure disorders
types:
-_____: Neurons unilaterally
-_____

A

Partial (focal) seizures

Status Epilepticus

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16
Q

Status Epilepticus
-Is a _____.

-A state of continuous _____ lasting more than _____ minutes, or second seizure is experienced before the person has fully _____ from the preceding seizure, or a single seizure lasts longer than _____ minutes. Resulting in _____ of the brain.

A
medical emergency
seizures
5
regained consciousness
30
hypoxia
17
Q

Partial (focal) seizures
-Focal (partial) Jacksonian seizures most often begin in the _____ and _____ and then progressively spread to other body parts.

A

face

fingers

18
Q

Complex partial seizure

-A complex partial seizure results is impaired _____, as well as the inability to respond to _____

A

consciousness

exogenous stimuli

19
Q

alterations in movement
huntingtons disease
-expansion of a _____ repeat stretch within the Huntingtin gene results in a different (_____) form of the protein, which gradually damages cells in the brain

  • Rare, _____ hereditary-degenerative disorder; _____ arm on chromosome _____
  • Severe degeneration of the _____ (_____ and _____ nuclei) and _____.
A
CAG triplet
mutant
autosomal dominant
short
4
basal ganglia
caudate
putamen
frontal cerebral cortex
20
Q

parkinson disease

  • Severe degeneration of the _____ (_____) involving the dopaminergic nigrostriatal pathway
  • -Loss of _____ in the _____ causes the below signs:
  • -_____: Cogwheel, plastic
  • -_____ and akinesia
  • -Resting _____
  • -_____: Postural fixation, equilibrium, righting
  • -_____ symptoms
  • -Cognitive-affective symptoms and _____
A
basal ganglia
corpus striatum
dopaminergic-pigmented neurons
substantia nigra
Rigidity
Bradykinesia
tremor
Postural abnormalities
Autonomic-neuroendocrine
dementia
21
Q

In Parkinson disease the basal ganglia influence the hypothalamic function to produce this clinical manifestations

  • _____
  • _____
  • _____

-Fragmented _____, _____, muscle _____ and _____

A
Inappropriate diaphoresis
Gastric retention
Urinary retention
sleep
depression
stiffness
bradykinesia
22
Q

motor neuron diseases
examples
-_____

A

Amyotrophic lateral sclerosis

23
Q

Amyotrophic LateralSclerosis
treatment
-Administer _____ (_____), an _____ which is standard treatment that prolongs life for months but does not _____.

A

riluzole (Rilutek)
antiglutamate
cure