PeerWise Questions

Question 1

Where is nausea recognised in the brain?

Answer 1

Anterior ínsula cortex

Question 2

The kidney excretes H+ by combining it with which two compounds?

Answer 2

NH3, HPO42-

Question 3

As a rule, a patient with acidaemia is also at risk of ?

Answer 3

hyperkalaemia

Question 4

What is the main cause of diabetic ketoacidosis?

Answer 4

low insulin

Question 5

Which of the following molecules is responsible for the fruity-breath of an individual who has DKA?

Answer 5

acetone

Question 6

What is the cut point for the diagnosis of diabetes using the HBA1C (in Moll/mol)

Answer 6

6.5%

Question 7

what kind of receptor is the calcium sensing receptor? what intracellular changes does it bring about?

Answer 7

GPCR

activates phospholipase C, blocking the stimulation of cAMP

Question 8

What is the active form of Vitamin D?

Answer 8

1,25(OH)2D

Question 9

What is cholesterol converted into by p450scc?

Answer 9

Pregnenolone

Question 10

what causes upregulation of phenylethanolmethyltransferase (PMNT)

Answer 10

cortisol

Question 11

Which enzyme converts cortisol to cortisone?

Answer 11

11beta HSD11

Question 12

Pain that is perceived in an organ contributes to its developmental region. What is the nerve supply to the appendix?

Answer 12

Umbilical (T8-T12)

Question 13

Which receptor does ADH bind to in the collecting duct? What type of receptor is this?

Answer 13

V2 - GPCR

Question 14

What is the Parathyroid hormone (PTH) effect on blood pH?

Answer 14

decrease pH

Question 15

Which two enzymes does glucagon inhibit in glycolysis?

Answer 15

PFK1, pyruvate kinase

Question 16

What are the receptors found in the lower urinary tract for the control of micturition and where specifically are they found?

Answer 16

M3 - Bladder
B3 - Bladder
A1 - Internal urethral sphincter
Nicotinic - External urethral sphincter