Non-surgical managment of lung cancer

Question 1

Describe adjuvant therapy

Answer 1

Post operative

Chemo = increase chance of cure

Question 2

Who can be given SABR and what does it do?

Answer 2

For unfit patients and involves giving high dose over a period of a week. Only for tumours up to 4cm

Question 3

What are one of the ways to measure Qol?

Answer 3

Painful bone metastases - RT single fraction

Brain mets. – resection, RT, steroids or erlotinib?

Question 4

For SCLC, what combination of drugs is commonly used?

Answer 4

Combination of drugs eg. cisplatin+ etoposide

Question 5

What are the side effects of chemo?

Answer 5

Marrow suppression (+ rosk of life threatening infection)
Nausea. Vomiting. GI upset. Mucositis. Fatigue. Lethargy.
Neuropathy. Increased risk MI/stroke. Renal impairment.
Hair loss. Nail changes.

Question 6

What are the side effects of radiotherapy?

Answer 6

General: Lethargy. Risk to surrounding organs
Acute: pneumonitis. Dysphagia
Late: Fibrosis. Stricture. Increased risk MI. 2nd malignancies

Question 7

What are common side effects of immunotherpy?

Answer 7

colitis, pneumonitis, dermatitis, endocrinopathies

Question 8

What does lung cancer screening involve?

Answer 8

For at risk population and involves low dose Ct.