hypersensitivity

Question 1

what is type 1 hypersensivity ?

Answer 1

allergy
IgE mediated
T cells sensitised to thing
mast cells brick it and release histamines

Question 2

what are features of eczema ?

Answer 2

common in children
exposed and flexor surfaces
degranulation of basophils and mast cells in response to sensitised IgE

Question 3

how do you investigate eczema ?

Answer 3

skin testing
patch testing
serum tryptase

Question 4

how do you treat eczema ?

Answer 4

antihistamines
corticosteroids
adrenaline
allergen avoidance

Question 5

what is a type 2 hypersensitivity reaction ?

Answer 5

blood types

antibodies to cell proteins on RBCs

Question 6

what is a type 3 hypersensitivity reaction ?

Answer 6

complexes
different cells fuses complexes of Ig
SLE example

Question 7

what is a type 4 hypersensitivity reaction ?

Answer 7

delayed
TH1 in response to adaptive immune response, 48 hours til reaction
contact dermatitis is reaction