Seizures in Childhood Lecture Powerpoint Flashcards

1
Q

Recall ictal, post ictal, tonic, clonic, activation procedures

A

ictal - related to or caused by stroke/seizure
post ictal - altered conscioussness after seizure
tonic - producing tone or contraction of muscles
clonic - alternating pattern of relaxation and contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

3 activation procedures to induce a seizure for EEG, 4 other labs utilized in seizure workup (4)

A
  • flashing bright lights
  • sleep deprivation study
  • hyperventiliation
  • MRI
  • labs to rule out metabolic abnormalities
  • LP
  • EKG
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Seizure causes (3)

A
  • mostly idiopathic
  • following hypoxic/ischemic attacks
  • head trauma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Epilepsy definition

A

Recurrent seizures unrelated to fever or acute cerebral insult, no discernable underlying provocation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Seizure is a ___ and epilepsy is a ___

A

symptom, diagnosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Infantile spasms

A

Brief motor spasms affecting trunk and extremities, similar to infantile startle reaction (morrow reflex), although momentary, can occur hundreds of times a day, fairly subtle and called hypsarhythmia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

lennox gastaut syndrome

A

Triad of mental retardation, absence and tonic seizures, and slow spike wave discharges on EEG, onset 2-7 years often have history of infantile spasms and status epilepticus as initial manifestation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Complex partial seizures (psychomotor seizures)

A

characteristically manifest with variety of motor, sensory, or behavioral alterations, motor activity may remain focal, with transient somnolence or confusion following often

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Rolandic (benign/simple) partial seizures

A

All symptoms of complex partial seizures but no altered consciousness, familial with very specific eeg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Juveniile myoclonic epilepsy (Janz syndrome)

A

recessively inherited epilepsy, neuroimaging typically reveals no abnormalities, clinical manifesetations include tonic clonic seizures, absence seizures, and myoclonus most frequently affecting the arms, distinct in that it isn’t associated with other neurologic abnormalities whcih carry a much worse prognosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Febrile seizures

A

most common seizure of childhood, tonic clonic seizure lasting 1-2 minutes with rapid return of consciousness, seizures tend to occur in conjunction with rapid rise in body temp (if sick with virus for example)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

atypical febrile seizures

A

those that have prolonged activity exceeding 15 min, focal seizure manifestations, or multiple seizures during same febrile illness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Absence (petit mal) seizures

A

Generalized seizures where absence spells may last up to 10 seconds and occur dozens of times daily, patients have no recollection of events durring seizures and will resume previous activity without postictal symptoms, may be preceded by hyperventilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Way to differentiate seizure from something like a hypnotic jerk

A

seizures normally have grimacing or neck stretching but most of all when grabbed don’t cease action - other movements do

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Status epilepticus and 3 subtypes

A

Seizure lasting greater than 30 minutes or serial seizures which there has been no return to same level of consciousness as occurred prior to seizure, 1 of 3 subtypes including prolonged febrile seizure, idiopathic status epilepticus, and symtomatic status epilepticus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Pediatric seizure cessation treatment regimen (4)

A
  • airway, breathing, circulation
  • dextrostix, draw blood for glucose
  • lorazepam, diazepam or if persists then anticonvulsants such as phenytoin (dilantin) and (phenobarbital first line in neonatal seizure)
  • control intracranial pressure with mannitol, dexamethasone
17
Q

Disorders that mimic seizures (5), and what is a test that can differentiate them? (1)

A
  • sleep myoclonus
  • night terror
  • migraine and syncope
  • benign proxysmal vertigo
  • psychogenic nonepileptic seizures

-prolactin levels will not be elevated in nonseizure conditions

18
Q

Post status epilepticus treatment regimen

A

maintenance doses of anticonvulsant such as phenytoin

19
Q

Drug of choice for absence seizures

A

Ethosuxamide

20
Q

4 drugs of choice for generalized and simple partial seizures including status epilepticus

A

Phenobarbital (generalized and simple partial including status epilepticus but no absent seizures), 2nd line phenytoin or valproic acid (generalized and partial) or carbamazepine (effective against partial and secondarily generalized but no absent seizures)

21
Q

Phenytoin (dilantin) side effects

A
  • gingival hyperplasia
  • hirsutisim
  • lymphadenopathy
22
Q

Tegretol (carbemazepine) side effects (3)

A
  • causes more seizures in the primary generalized epilepsy
  • hyponatremia
  • leukopenia
23
Q

Phenobarbitol side effects (2)

A

Sedation

Confusion

24
Q

Anticonvulsant withdrawal

A

May be attempted slowly after 2 years of seizure free activity in child with no underlying disease