ASPIRIN EXACERBATED PULMONARY DISEASE

Question 1

ASA EXACERBATED PULMONARY DISEASE

Answer 1

EXACERBATION OF ASTHMA AND RHINITIS
FOLLOWING ASA OR NSAIDS

MAY BE IN 10% OF ASTHMATICS
TAKES 1-5 YEARS TO DEVELOP
THEN, ATTACK OCCURS IN 3 HOURS

Question 2

ASPIRIN TRIAD

Answer 2

ASTHMA
ANOSMIA, SINUSITIS
NASAL POLYPOSIS

Question 3

DX OF ASA DISEASE

Answer 3

PROVOCATION TESTING WITH INCREASING DOSES

OF ASA

Question 4

PREVENTION

Answer 4

ANY COX 1 INHIBITORS SHOULD BE AVOIDED
CAN USE SODIUM SALICYLATE AND SALICYLAMIDE
TYLENOL IS WEAK INHIBITOR OF COX1 AND COX2
AND CAN BE USED IN LOW DOSES