Development L6 - Palate

Question 1

the palatal shelves meet at the midline to form the what?

Answer 1

medial edge epithelium, which bond to form the medial edge epithelium seam.

Question 2

palatal shelve elevation is said to be a result of intrinsic and extrinsic force, which force involves the tongue.

Answer 2

extrinsic forces

Question 3

describe what happens during week 8 in reference to the tongue

Answer 3

continued foetal development of the oro-naso cavity results in the withdrawl of tongue inferiorly

Question 4

osteoblasts that trapped in the bone are called what

Answer 4

osteocytes

Question 5

formation of the MME seam triggers a series of biochemical and cellular reactions causing what

Answer 5

degeneration of the MEE seam

Question 6

the formation of the palate occurs during which weeks

Answer 6

male: 6-12 weeks

female 7-12 weeks

Question 7

]. The contact of the palatal shelves initiates adhesion between the two MEE layers, forming the?

Answer 7

MME seam

Question 8

the development of the palate occurs at which cavity

Answer 8

oro-naso cavity

Question 9

during weeks 7-8 intramembranous ossfication occurs, what do mesenchymal cells differentiate to facilitate intramembranous ossification

Answer 9

mesenchmyal cells differentiate to osetoblasts

Question 10

what irole does the secondary palate have

Answer 10

separates the nasal airway and the oral cavity

important for:

mastication - bolus formation

sensation - tase and texture

speech

Question 11

what three factors result in the withdrawl of the tongue

Answer 11

head lifting from cardiac plate

meckels cartilage growth

increase in height of nasal cavity

Question 12

what do osteblasts deposit to produce bone

Answer 12

osteoid

Question 13

the primary palate is derived from what?

Answer 13

fused nasal prominences with inter-maxillary segment

Question 14

what stage in devlopment is the foetus (weeks)

and which three features are being developed

Answer 14

foetus is at 6 weeks in development

during the 6th week the following is developed

1. development of the palatal shelves
2. development of the tongue, which moves superiorly
3. development of the nasal septum

Question 15

what would you expect to see in reference to the palatal shelves during week 7

Answer 15

continued growth of palatal shelves.

the palatal shelves would be vertically orientated due to the large tongue

Question 16

the downward movement of the tongue allows teh palatal shelves to do what?

Answer 16

the palatal shelves flip in a horizontal position.

Question 17

what are the three palatal fusion theories out there

Answer 17

EMT = epithelial - mesenchymal transition

Question 18

palatal shelve elevation is said to be a result of intrinsic and extrinsic factors, which force is generated within the palate

Answer 18

intrinsic forces

Question 19

what occurs during week7-8 in the primary palate

Answer 19

intramembranous ossification occurs at the ossification centres around the perpendicular plate.

Question 20

hyaluronan acts as a intrinsic factor, what role does hyaluronan have in palatal shelve elevation

Answer 20

hyaluronan accumulates prior to elevation, it brings in water and allows for the hydration of the extracellular matrix,. the pressure of the water helps push the palatal shelves in to a horizontal position.

Question 21

whcich signalling protein results in the formation of filopodia

Answer 21

TGFβ3

Question 22

what would you expect to see during week 7 in reference to the tongue

Answer 22

the continued growth of the tongue sees that it occupies a large proportion of the oro-nasal cavity.

Question 23

the primary palate sets the boundaries between which components

Answer 23

oral and nasal components