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Gastrointestinal > Medical Consequences of Alcohol Excess > Flashcards

Medical Consequences of Alcohol Excess Flashcards

1
Q

how many units of alcohol a week are recommended in alcohol guidelines

A

14 - spread over 3 days or more

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2
Q

where is alcohol death most common

A

men < 65

scotland

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3
Q

acute effects of excess alcohol consumption

A

CNS
GI
respiratory

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4
Q

CNS acute effects of excess alcohol consumption

A

accidents

violence

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5
Q

GI acute effects of excess alcohol consumption

A

oesophagitis
gastritis/ulceration
acute pancreatitis

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6
Q

respiratory acute effects of excess alcohol consumption

A

overdose

aspiration

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7
Q

chronic effects of excess alcohol consumption

A 
GI 
CNS
cardiovascular 
hematologic 
musculoskeletal 
endocrine 
dermatologic 
reproductive
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8
Q

GI chronic effects of excess alcohol consumption

A

stomach
liver
pancreas

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9
Q

cardiovascular chronic effects of excess alcohol consumption

A

hypertension
cardiomyopathy
MI
stroke

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10
Q

CNS chronic effects of excess alcohol consumption

A

neuropathies
cerebellar degeneration
dementia
wernicke-korsakoff’s syndrome

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11
Q

effects of underage drinking on the brain

A

smaller hippocampal areas than non-drinkers
greater activity in brain linked to;
reward
desire
positive effect
episodic recall in response to alcohol advertisements

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12
Q

hematologic chronic effects of excess alcohol consumption

A

anaemia

bone marrow suppression

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13
Q

musculoskeletal chronic effects of excess alcohol consumption

A

proximal myopathy

osteoporosis

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14
Q

what is foetal alcohol syndrome

A

children exposed to alcohol in uterus

7-14 drinks (>5 per occasion) can cause moderate damage to foetus

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15
Q

effects of baby due to foetal alcohol syndrome

A

growth deficiency
mental retardation/intellectual impairment
attentional learning disabilities
behavioural problems

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16
Q

how does alcohol effect the liver

A

alcohol metabolism;
cirrhosis
alcohol hepatitis

17
Q

signs of chronic liver disease

A

stigmata - spiders, fetor, encephalopathy
‘synthetic dysfunction’
prolonged PT
hypoalbuminaemia

18
Q

signs of portal hypertension

A

caput medusa
hypersplenism
Thrombocytopenia (pancytopenia)

19
Q

how is cirrhosis staged

A

childs-turcotte Pugh

model for end stage liver disease (MELD)

20
Q

LFTs of alcoholic hepatitis

A

bilirubin > 80

AST <500 - 10 fold increase (AST:ALT ration > 1.5)

21
Q

characteristic features of alcohol hepatitis

A

hepatomegaly
fever
leucocytosis
hepatic bruit

22
Q

scoring for alcoholic hepatitis

A

maddrey’s discriminant function

Glasgow alcoholic hepatitis score

23
Q

treatment for alcoholic hepatitis

A

Prednisolone

Pentoxifylline

Gastrointestinal (71 decks)

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