Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pathology > Lymphoma > Flashcards

Lymphoma Flashcards

1
Q

how can a lymphoma present?

A

a lump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what should you ask in a history of a lump?

A
  • site
  • has this enlarged, got smaller or remained the same
  • over what time period
  • pain or redness
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

which are the B symptoms?

A
  • fever
  • night sweat
  • weight loss
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which systems should be covered in the systemic enquiry?

A
  • neurological
  • musculoskeletal
  • cardiorespiratory
  • gastrointestinal
  • genitourinary
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what should you note in a lump examination?

A
  • size
  • consistency
  • tenderness
  • overlying erythema or skin changes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

radiological investigations to confirm a lymphadenopathy

A
  • ultrasound
  • CT scan
  • PET-CT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

differential diagnosis for lymphadenopathy

A
  • infection
  • solid tumour
  • lymphoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

blood investigations

A
  • CBC
  • ESR and CRP
  • U&E and Creatinine
  • LFTs
  • serum Ca, albumin, LDH, uric acid
  • serum protein electrophoresis and Igs
  • ANA
  • HIV, TORCH, EBV, HBV, HCV
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

histological investigation

A
  • biopsy with H&E and immunology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what are the stages of lymphoma?

A

Stage 1: involvement of a single node region or lymphoid structure
Stage 2: involvement of 2 or more node regions on the same side of the diaphragm
Stage 3: involvement of lymph regions or structures on both sides of the diaphragm
Stage 4: involvement of extranodal site(s) beyond that designated E

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

types of B-cell lymphoma

A
  • high-grade

- low-grade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

types of high-grade B-cell lymphoma

A
  • Hodgkin’s lymphoma

- diffuse large B-cell lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

features of Hodgkin’s lymphoma

A
  • can be nodular
  • nodular sclerosing
  • mixed cellularity
  • lymphocyte rich
  • lymphocyte depleted
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what are the subtypes of diffuse large B-cell lymphoma based on?

A
  • morphology (centroblastic, immunoblastic, anaplastic, plasmablastic)
  • genetic (germinal centre vs activated phenotype)
  • immunological
  • disease characteristics (CNS, cutaneous leg type, mediastinal, intravascular, effusion)
  • infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

types of low-grade B-cell lymphoma

A
  • Small Lymphocytic Lymphoma
  • Mantle Cell Lymphoma
  • B-Prolymphocytic Leukaemia
  • Follicular Lymphoma
  • Splenic Marginal Zone Lymphoma
  • Marginal Zone Lymphoma (Nodal vs Extranodal)
  • Hairy Cell Leukaemia
  • Lymphoplasmacytoid Lymphoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

types of T-cell lymphoma

A
  • high-grade

- low-grade

17
Q

indications of low-grade disease being treated

A
  • B symptoms
  • progressive disease
  • BM failure
18
Q

treatment for lymphoma

A
  • chemotherapy

- bone marrow transplant (if relapsed)

Pathology (21 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions