Inhalational Flashcards

1
Q

What are examples of inhalational anaesthetics?

A
Halothane 
Isolfularane
Sevoflurane
Deflurane
Enflurane
Metoxyflurane
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2
Q

What are exmaples of carriers for inhaltional anaesthetics?

A

Oxygen, nitrous oxide and carbon dioxide

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3
Q

When is oxygen used at 100%?

A
100% pure oxygen given to animals with:
anaemia
pulmonary pathology 
hypoventilation 
animals recovering  from N2O anaesthesia/supplied during recovery if needed
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4
Q

What colour are the 2 types of carrier gas cyclinders?

A

Oxygen - black with white shoulders

Nitrious oxide - blue

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5
Q

What concentration is nitrous oxide given at?

A

2:1 N2O:O2 mixtures (double oxygen in non-rebreathing circuits and 1:1 in rebreathing circuits)
Given at 66% delivered

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6
Q

What is nitrous oxides second gas effect?

A

It enhances the uptake of halothane therefore allowing faster induction of anaesthesia

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7
Q

what care needs to be taken with nitrous oxide?

A

Do not use more than 80% N2Oas will lower oxygen levels below normal
N2O diffuses into gas-filled spaces and acculumates
Delivering N2O to a apteint with pathologica abdominal or thoracic distension should be avoided
Giving N2O to a patient with pneumothorax can cause it to double in size in 10mins
Do not use in bowel obstruction or middle ear disease

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8
Q

Describe diffusion hypoxia

A

Due to the fact that nitrous oxide has low solubility in blood, at the end of anaesthesia when N20 administration cease sthe N2O present in blood diffuses back into the alveoli and ‘dilutes’ the alveolar air so less oxygen is available.

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9
Q

Give advantages of inhalational anaesthesia

A

Depth of anaesthesia readily altered
Concentration of anaesthetic in blood or brain may be altered rapidly by changing vaporiser setting
Elimination of inhaled agents occurs mainly via the lungs therefore advantage is liver/kidney patient
Allows constant delivery of oxygen alongside patient
Most patients are intubated therefore IPPV may be performed and anaesthetic is safer

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10
Q

Give disadvantages of inhalational anaesthesia

A

Need for anaesthetic machine and range of equipment (cost)
Hazards, personnel health risk, explosion risk
Knowledge required of circuits and machine
Induction and recovery possibly delayed due to lung pathology

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11
Q

Describe the minimum alveolar concentration (MAC)

A

Measure of anaesthetic potency, defined as quantity of anaesthetic required to immobilize 50% of patients.
Agents with lower MAC valve are most potent

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12
Q

Describe the blood gas solubility

A

A measure of how readily the volatile agent dissolves into plasma

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13
Q

Give examples of inhalational agents

A
Halotahne
Isofularne
Sevoflurane 
Desflurane
Eniflurane
Methoxyflurane 
Ether
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14
Q

Give advantages of isoflurane

A

Good muscle relaxation
Analgesia
Fast recovery

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15
Q

Give Advantages of sevoflurane

A
Rapid induction 
Rapid recovery 
Pleasant odour 
Well tolerated for mask induction 
Non-irritant
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16
Q

Give disadvantages of isoflurane

A

Can cause hypotension
Dose dependant respiratory depression
Pungent odour so not mask induction tolerated
Airway irritant

17
Q

Give disadvantages of sevoflurane

A

Dose dependant cardiovascular and respiratory depression

Unstable in presence of soda lime leading to formation of compound A (this is nephrotoxic to rats)