9/5/13

Question 1

In combination with local anesthetics, this drug prolongs the duration of action and decreases toxicity by reducing absorption

Answer 1

Epinephrine

Question 2

What receptors does epinephrine act on

Answer 2

alpha 1 and 2, beta 1 and 2

Question 3

Drug of choice during anaphylactic shock

Answer 3

Epinephrine (treats severe hypotension and bronchial constriction)

Question 4

Epinephrine decreases insulin secretion because of this receptor

Answer 4

alpha 2

Question 5

Drug used mainly for severe shock

Answer 5

Norepinephrine (no beta 2 receptors)

Question 6

Which receptors does norepinephrine act on

Answer 6

alpha 1 and 2, beta 1

Question 7

Phlebitis, tissue sloughing, arryhythmias, and increased myocardial oxygen demand are adverse reactions of this drug

Answer 7

Norepinephrine

Question 8

Isoproterenol acts on which receptors

Answer 8

Beta 1 and 2

Question 9

This drug is used to treat COPD/Bronchial constriction, heart block, acute heart depression, and Long Q-T syndrome

Answer 9

Isoproterenol

Question 10

Albuterol acts on which receptors

Answer 10

Beta-2

Question 11

Mainly used for bronchial constriction but also was once used for relaxation during premature birth

Answer 11

Albuterol

Question 12

Dobutamine acts on which receptors

Answer 12

beta-1

Question 13

What are the advantages of using dobutamine instead of epinephrine or norepinephrine?

Answer 13

Dobutamine can affect the inotropy of the heart without affecting the blood pressure that much

Question 14

Major effect of this drug, which in higher doses binds to beta 1 receptors, is renal vasodilator

Answer 14

Dopamine

Question 15

Adverse reaction to this drug includes rebond hyperemia, ischemic damage o nasal mucosae, hypertension, and urniary retention

Answer 15

Phenylephrine

Question 16

Phenylephrine acts on which receptors

Answer 16

alpha 1

Question 17

Clonidine acts on which receptors

Answer 17

alpha 2

Question 18

Used to treat withdrawal symptoms and is also an antihypertensive drug

Answer 18

Clonidine

Question 19

This sympathomimetics drug is reuptake inhibitor for serotonin, NE, and dopamine

Answer 19

Cocaine

Question 20

This substance is found in beer and cheese, and these products cannot be ingested when MAO is inhibited

Answer 20

Tyramine

Question 21

This type of amphetamine-like drug is used to treat ADHD

Answer 21

methylphenidate

Question 22

How do amphetamine like drugs work?

Answer 22

They travel through the re-uptake transporters in the terminal and displace stored cathecolamine neurotransmitter from the vesicles

Question 23

A mixed sympathomimetic drug that is a decongestant, antihypotensive, and antiashmatic

Answer 23

ephedrine and pseudoephedrine

Question 24

Phentolamine is a competitive blocker of which receptors

Answer 24

alpha 1 and alpha 2

Question 25

This drug is used as a short term control of hypertension due pheochromocytoma and has adverse affects of tachycardia, postural hypotension, and GI irritation

Answer 25

phentolamine

Question 26

Phenoxybenzamine is a non-competitive, irreversible blocker of which receptors

Answer 26

alpha 1 and alpha 2

Question 27

This drug lowers the blood pressure and enhances the sympathetic reflex activity resulting in increased heart rate and contractile force. Adverse reactions include tachycardia, postural hypotension and nasal stuffiness

Answer 27

Phenoxybenzamine

Question 28

Prazosin (any zosin) is a competitive blocker of which receptors?

Answer 28

Alpha 1

Question 29

This drug reduces hypertension without the side effect of tachycardia, also can help relieve obstruction of urinary tract in BPH

Answer 29

prazosin (if alpha 2 is blocked, NE release is not inhibited and thus can lead to overstimulation of the heart. Prazosin is a selective alpha 1 blocker)

Question 30

Tamusulosin acts on this type of specific alpha receptor found in the prostate

Answer 30

alpha 1a

Question 31

Propranolol blocks these receptors

Answer 31

Beta 1 and 2 (first generation beta blockers)

Question 32

This drug treats arrhythmias, angina pectoris, hypertension, decreases MI mortality, migraines, and stage fright

Answer 32

Propranolol

Question 33

The adverse side effects of this drug include cardiac depression, asthma attacks, CNS depression, delayed response to hypoglycemia, and rebound angina pectoris

Answer 33

Propranolol

Question 34

Drug used for glaucoma that is similar to propranolol

Answer 34

Timolol

Question 35

Metoprolol blocks this type of receptor

Answer 35

beta 1 (second generation blocker)

Question 36

This drug is antihypertensive, antiarrhytimic, treats angina pectoris and CHF and does not precipitate asthma attacks

Answer 36

Metoprolol (esmolol in emergency settings)

Question 37

Third generation beta blocker that block beta 1 and 2, alpha 1 used to treat hypertension and CHF

Answer 37

Carvedilol

Question 38

This drug displaces NE from storage vesicles without releasing them into the synapse and can cause suicidal thoughts, used to treat hypertension

Answer 38

resperine

Question 39

Drug can cause transient hypertension after displacing and releasing NE from the storage vesicles in the presynaptic terminal

Answer 39

Guanethidine