9- Clinical and pathological changes seen in viral infections

Question 1

Describe the clinical signs of cat ‘flu’

Answer 1

Nasal discharge
ocular discharge
pyrexia
anorexia
lethargy

Question 2

T/F FHV (feline herpes virus) causes ocular ulceration

Answer 2

False FCV (feline calcivirus virus) causes ocular lesions
FHV causes corneal ulcers

Question 3

Describe the clinical signs of canine parvovirus

Answer 3

vomiting
bloody diarrhoea
pyrexia
neutropenia

Question 4

Which viruses can cause cancer

Answer 4

Retroviruses
Some Herpesviruses
Papillomaviruses

Question 5

List 2 examples of viruses that can cause immunosupression

Answer 5

FIV
Infectious Bursal Disease
BVDV
Parvoviruses

Question 6

List a virus that can cause immunopathology

Answer 6

FIP (Feline Infectious Peritonitis)

Question 7

What pathological changes are generally seen with viral diseases

Answer 7

Dependent on disease process
Tissue damage due to cell death
Inflammatory response
Diagnosis of viral disease typically requires identification of virus antigen

Question 8

What viruses cause inclusion bodies

Answer 8

Some Herpesvirus or Poxvirus infections
e.g. IBR

Question 9

List 2 viruses that cause pre-natal infections

Answer 9

Pestiviruses- BVD, Border disease
Schmallenberg virus

Question 10

What physiological changes do you see with canine parvovirus

Answer 10

Villus stunting
crypt dilation
necrosis of cells