9 - Materia Media for Managing Cancer: The Cytotoxic Herbs Flashcards
(56 cards)
What is the main principle behind using cytotoxic herbs in cancer treatment?
Big disease takes big medicine
Why is it important to have qualified practitioners access cytotoxic herbs?
They can kill both cancer cells and healthy cells, requiring specific dosing and monitoring
What is the recommended duration for using cytotoxic herbs?
For the shortest duration possible, with monitoring to determine when to stop
What should be done if cancer is controlled but not cured?
Consider a low-dose cytotoxic rotation for a longer duration
What is the first guideline for prescribing cytotoxic herbs?
Start low and go slow
What should be anticipated when prescribing cytotoxic herbs?
Side effects
What is one of the specific tissue targets for Artemisia annua?
Broadly active against various types of cancer
What mechanism does Asimina triloba use to assist in cancer treatment?
Inhibits multidrug resistance pumping and helps keep chemotherapy in target cells
What are the notable effects of Camptotheca acuminata?
Inhibition of topoisomerase I and induction of apoptosis
Which alkaloids does Chelidonium majus contain that are significant in cancer treatment?
Isoquinoline alkaloids
What is the primary action of Larrea divaricata in cancer management?
Induces apoptosis and inhibits glycolysis
What are the specific uses for Phytolacca spp.?
Active against various types of cancer, particularly breast and throat
What does Podophyllum peltatum inhibit to prevent cancer cell mitosis?
DNA topoisomerase II and tubulin polymerization
What effects do Sanguinaria canadensis alkaloids have?
Antimicrobial and anti-inflammatory effects
What is the mechanism of Taxus brevifolia in cancer treatment?
Overstabilizes tubulin and inhibits mitosis
What is the proapoptotic mechanism of Thuja occidentalis?
Induction of ROS and p53 activation
What role does Viscum album play in cancer treatment?
Inhibits cell replication and upregulates NK cells
What is the common name for Artemisia annua?
Annual wormwood
Fill in the blank: The molecular structure of artemisinin shows the _______.
endoperoxide bridge
What is the recommended dosing approach for Artemisia?
Pulse dosing in alternating weeks
What are some synergists for Artemisia?
- Grapefruit juice
- Vitamin C
- Omega-3 fatty acids (DHA and EPA)
- Iron
- Proteolytic enzymes
- Lymphatic and hepatic support
- Butyrate
What is the common name for Asimina triloba?
Pawpaw
What is a significant concern regarding Camptotheca acuminata?
It is considered endangered due to overharvesting
What is the common name for Chelidonium majus?
Greater celandine