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9: Myopathies Flashcards

(9 cards)

1
Q

What are common myopathy signs?

A

Stiffness and reluctance to mvoe

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2
Q

Why do many myopathies look similar?

A

Skeletal muscle has a limited pathological response

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3
Q

Where is CK produced?

A

Skeletal and cardiac muscle

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4
Q

After how long does CK peak?

A

4-6 hours and then cleared in days

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5
Q

Where is AST produced?

A

Skeletal and cardiac muscle, liver, RBCs etc

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6
Q

After how long does AST peak?

A

12-24 hours and cleared in 2-3 weeks

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7
Q

How can you diagnose a myopathy?

A

Submaximal exercise test and take blood samples pre-exercise and 4-6 hours later

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8
Q

What degree of CK rise suggests a sub-clinical exertional myopathy?

A

2-3x

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9
Q

How can you differentiate trauma and fibrosis?

A

Ultrasound

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