9. Syphilis Flashcards

(36 cards)

1
Q

(Lues)

Stadien (7)

A
  • primäre-
  • sekundäre-
  • latente Frü-
  • latente Spät-
  • tertiäre-
  • quartäre-
  • konnatale
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2
Q

(Lues)

primäre-: Befunde (2)

A
  • Ulcus durum
  • schmerzlose reginäre Lymphadenopathie
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3
Q

(Lues)

Ulcus durum

A

schmerzloses hartes Ulkus

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4
Q

(Lues)

sekundäre-: Befunde (6)

A
  • Condylomata lata
  • Alopecia specifica areolaris
  • Plaques muqueuses
  • polymorphes Exanthem
  • Polyskleradenitis
  • Lues maligna
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5
Q

(Lues)

Condylomata lata

A

nässende erodierte Papeln

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6
Q

(Lues)

Alopecia specifica areolaris

A

Mottenfraß-ähnlicher Haarausfall

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7
Q

(Lues)

Plaques muqueuses

A

papulopustulöse Enantheme

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8
Q

(Lues)

polymorphes Exanthem: Charakteristik (2)

A
  • anfangs makulös
  • spätestens papulös
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9
Q

(Lues)

Polyskeradenitis

A

harte Schwellung vieler Lymphknoten

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10
Q

(Lues)

Lues maligna

A

multiple Ulzerationen

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11
Q

(Lues)

latente Früh-: Definition

A

symptomfreies Intervall im ersten Jahr

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12
Q

(Lues)

latente Spät-: Definition

A

symptomfreies Intervall nach einem Jahr

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13
Q

(Lues)

tertiäre-: Befunde (2)

A
  • Gummen
  • kardiovaskuläre Syphilis
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14
Q

(Lues)

Gummen

A

granulomatöse Gewebeveränderungen

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15
Q

(Lues)

quartäre-

A

Neurosyphilis

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16
Q

(Lues)

konnatale-: Leitsymptom

A

Hutchinson Trias

17
Q

(Lues)

Hutchinson Trias

A
  • Keratitis parenchymatosa
  • Innenohrschwerhörigkeit
  • Tonnenzähne
18
Q

(Lues)

Infektiosität

A

hoch (insb. in Stadien I und II)

19
Q

(Lues)

Diagnostik (3)

A
  • Suchtest
  • Bestätigungstest
  • Aktivitätstest
20
Q

(Lues)

Suchteste

21
Q

(Lues)

TPPA

A

Treponema-pallidum-Partikel-Agglutinationstest

22
Q

(Lues)

TPHA

A

Treponema pallidum-Hämagglutinationstest

23
Q

(Lues)

Bestätigungstest

24
Q

(Lues)

FTA-Abs

A

Fluoreszenz-Treponema-AK-Absorption

25
(Lues) Aktivitätstest
VDRL
26
(Lues) VDRL: AK
anti-Cardiolipin
27
(Lues) VDRL
Veneral Disease Research Laboratory
28
(Lues) Therapie der Wahl
Benzathin-Penicillin G
29
(Lues) Therapieentscheidung
- bei Frühsyphilis - bei Spätsyphilis - bei Neurosyphilis
30
(Lues) Benzathin-PenicillinG-Gabe bei Früh-
einmalige i.m. Gabe
31
(Lues) Benzathin-PenicillinG-Gabe bei Spät-
dreimalige i.m. Gabe verteilt über 15d
32
(Lues) Benzathin-PenicillinG-Gabe bei Neuro-
i.v. Gabe
33
(Lues) Penicillin i.m.: Nebenwirkung
Jarisch-Herxheimer-Reaktion
34
(Lues) Herxheimer-Reaktion: Pathophysiologie
akute systemische Entzündungsreaktion auf bakterielle Endotoxine
35
Jarisch-Herxheimer-Reaktion: Therapie
Glucocorticoide i.v.
36
(Lues) Therapie: alternative Wirkstoffe (3)
- Doxycyclin - Erithromycin - Ceftriaxon