Maternal CNS Changes Flashcards by Rachel Oakman | Brainscape

Q

MAC progressively decreases during pregnancy due to:

A

Hormonal (progesterone) changes

increased level of Beta-endorphin

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Q

_______sensitivity to LA, therefore reduce dose up to ___%

A

Increase, 30%

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Q

Obstruction of IVC by gravid uterus causes:

A

Distension of epidural venous plexus
Increase epidural blood volume
- decreased spinal CSF volume
-decreased potential volume of epidural space
(these will increase cephalad spread of LA during spinal and epidural anesthesia.)
-increased epidural pressure.

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