Hypogonadism Eval/management

Question 1

Viral Orchitis cause

Answer 1

Mumps

Question 2

Noonan’s Syndrome

• S/S:
• Features

Answer 2

• S/S: Webbed neck, low ears, ptosis, , short, lymphedema, right heart disease, pectus excavatum.
• F: Normal external genitalia. Maybe cryptorchidism

Question 3

Testicular Feminization

• Genetics
• Features
• Tx

Answer 3

• G: Female 46 XY X-linked Recessive
• F: Phenotypic females, but little or no axillary or pubic hair. Normal breast development. No menarche. Blind vaginal pouch; Have testicles… in inguinal canals or labia majora, or abdomen.
• Tx: Remove testes due to risk of malignancy

Question 4

Reifenstein’s Syndrome

Answer 4

• partial androgen resistance

- S/S: Pubic/axillary hair, gynecomastia, incomplete male characteristics; sometimes only infertility

Question 5

Kallmann’s Syndrome

Answer 5

Impairment of synthesis and/or release of gonadotropin-releasing hormone(GnRH)
Low levels of LH & FSH
Associated with anosmia

Question 6

Testosterone Treatments

Answer 6

• Daily Testosterone Patch OR

- Parenteral of long-acting ester at 1 week to 3 week intervals (test enanthate/cyclopentyl propionate)

Question 7

Causes of ED in men

Answer 7

1. Endocrine (Testicular failure or Hyperprolactinemia)
2. Drugs (Antiandrogensl Antihypertensives; Anticholinergics; CNS Drugs)
3. Penile Disease (Peyronie’s; Priapism trauma)
4. Neurologic Dx
5. Vascular Dx

Question 8

Contra for Sildenafil, LEvitra, or Cialis Tx

Answer 8

Nitrate Therapy for CHF

Question 9

Gynecomastia Paraneoplastic Endocrine Syndrome

Answer 9

Tumors that secrete hCG