Liver diseases Flashcards
Histologically, the liver is composed of
hepatocytes, bile canaliculi and hepatic sinusoids
Portal triad is composed of:
bile duct, hepatic artery and hepatic portal vein
Porta hepatis is composed of
hepatic artery, hepatic portal vein and commun hepatic duct
Hepatocytes secrete ____ of bile per day
800-1000 ml
Bile pH
7.6-7.8
Components of the bile
water, bile salts, cholesterol, lecithin, bile pigments and ions
Main function of bile salts is
emulsification
____ is a product of the hemoglobin.
Bilirubin
When we have high concentration levels of billirubin in blood we produce
jaundice
Billirubin concentration in hyperbilirubinemia
> 2.5-3mg/dL
Jaundice is a result of:
Post-hepatic obstruction of bile flow
Intrahepatic obstruction
Prehepatic excessive production of unconjugated bilirubin
Symptoms of jaundice are
yellow pigmentation of skin, mucous membrane and sclera
Risk factor of cholelithiasis
Age Obesity Diet (high fat and cholesterol) Rapid weight loss Pregnancy
Symptoms in cholelithiasis
Abdominal pain
Nausea and vomiting
Jaundice
Leukocytosis
Types of cholelithiasis
Cholesterol
Bilirubin
Mixed
