Nervous system PHARM

Question 1

AChE inhibitors: indirect cholinergic agonists

increasing acetylcholine

Answer 1

ANTI ALZHEIMERS

Question 2

DONEPEZIL : AChE inhibitor

Answer 2

dementia symptom control`

Question 3

RIVASTIGMINE : AChE inhibitor

Answer 3

parkinsons AND dementia

Question 4

MEMANTINE

Answer 4

• *blocks NMDA-type glutamate receptors
• modest effect on moderate to severe alzheimers
• slows down nerve cell loss

Question 5

dopamine precursors

Answer 5

levocopa-carbodopa

Question 6

dopamine agonists - bind to dopamine receptors

Answer 6

BROMOCRIPTINE

PRAMIPEXOLE

Question 7

BROMOCRIPTINE

Answer 7

dopamine agonist also acts on pituitary gland

can cause pulmonary fibrosis

Question 8

PRAMIPEXOLE

Answer 8

can be used in cojmbo with levodopa

Question 9

ANTICHOLINERG for parkinsons

Answer 9

benztropine :

use diphenhydramine if cants use benztropine

Question 10

SCOPOLAMINE

Answer 10

anticholinergic
muscle problems

motion sickness

Question 11

AMANTADINE

Answer 11

parkinsons - NMDA glutamate receptor antagonist (LIKE MEMANTINE-alzheimers)
levodopa induced dyskinesia LATE IN DISEASE

can exacerbate mental illness

Question 12

muscle spasticity in MS

Answer 12

botulinum toxin
baclofen (taper off if discontinuing)
tizanidine

Question 13

immune modulator for MS RELAPSING FORM

Answer 13

GLATIRAMER ACETATE

• L-GLUTAMINE, LYSINE, ARGININE
• PREG B

Question 14

FINGOLIMOD

Answer 14

MS RELAPSING FORM

do not use with class I (NA+)or III (K+) antiarrythmias

Question 15

LAMOTRIGINE

Answer 15

epilepsy and bipolar I

SE: serious skin rash
suicidal behavior and ideation

Question 16

TOPIRAMATE

Answer 16

EPILEPSY AND MIGRAINES

suicidal behavior and ideation
unexplained death in epilepsy
**lots of probs
PREG D: DONT! !!

Question 17

VALPROATE (merci)

Answer 17

epilepsy, mania, migraine

suicidal behavior
birth defects

Question 18

HALOPERIDOL AND PROCHLORPERAZINE

Answer 18

CLASSICAL ANTIPSYCHOTICS

PROCHLOROPERAZINE (USED MORE FOR VOMITING)

C/I IN PARKINSONS

Question 19

CLONODINE

Answer 19

A2

Question 20

PHENTERMINE

Answer 20

FASTIN :WEIGHT LOSS

AUGMENT DOPAMINE

PREG CATEGORY X

Question 21

ZOLPIDEM

Answer 21

AMBIEN

PERFORM COMPLEX NATURAL BEHAVIORS

Question 22

SUMATRIPTAN

Answer 22

MIGRAINE RELIEF

Question 23

BOTULINUM TOXIN

Answer 23

OVERACTIVE BLADDER, CHRONIC MIGRAINE
SPASTICITY

CAN GET PARALYSIS IN OTHER AREAS

Question 24

ANTI-SEIZURE

Answer 24

CARBAMAZEPINE

PHENYTOIN: can cause

Question 25

PHENYLZINE: MAOI

Answer 25

• ONLY USE WHEN OTHER ANTIDEPRESSANTS HAVE FAILED

**CAN CAUSE TYRAMINE TOXICITY
DON’T EAT CHOCOLATE / COFFEE

Question 26

MODANAFIL

Answer 26

get in the mode: dont fall asleep: anti narcopleptic

Question 27

CARBAMAZAPINE

Answer 27

anti convulsant and anti neurologic for epilepsy and neuralgias