MSK Pharm Flashcards
Selective Estrogen Receptor Modulator (SERM)
Raloxifene
Raloxifene
Estrogen modulator and Bone health
SE: Most common: hot flashes
endometrial cancer
increased risk of DVT (like birth control)
Bisphosphonate for osteoperosis
ALENDRONATE
take an upright position 30 mins before food with full glass of plain water
SE: esophageal erosion/ c/i in esophageal pathology
black tarry stools and coffee ground vomit
nutrients depleted with opioids
folic acid
vitamin C
iron
potassium
allopurinol
preventing further GOUT attacks
prevention of uric acid nephropathy during cancer chemo
SE: GI upset and maculopapular rash
colchicine
acute or first time GOUT
which steroids are oral
prednisone
prednisolone
methylprednisolone
dexamethasone
hydrocortisone
which steroids are oral
prednisone
prednisolone
methylprednisolone
dexamethasone
hydrocortisone
which steroids are inhaled
fluco
Celecoxib
cox 2 selective inhibitor
in osteoarthritis, rheumatoid arthritis (RA), and ankylosing spondylitis; management of acute pain in adults; treatment of primary dysmenorrhea; relief of signs and symptoms of juvenile RA
Celecoxib
cox 2 selective inhibitor
in osteoarthritis, rheumatoid arthritis (RA), and ankylosing spondylitis; management of acute pain in adults; treatment of primary dysmenorrhea; relief of signs and symptoms of juvenile RA
if taken with FLUCANAZOLE: increases concentration of the drug
muscle relaxant
Cyclobenzaprine, Flexeril
Methocarbamol, Robaxin: may turn urine black, blue, or green
Muscle Spasticity
Botulinum toxin, Botox
upper/lower limb spasticity
Baclofen, Lioresal : for MS not parkinsons
MoA unknown
Uses: spasticity of MS, spinal cord injury, rheumatic disorders. NOT indicated for stroke, cerebral palsy, and Parkinson’s disease has not been established and, therefore, it is not recommended for these conditions
TAPER off if discontinuing (hallucinations/seizures)
SE: drowsiness, asthenia, dizziness, headache, nausea
Tizanidine, Zanaflex: Alpha-2-adrenergic agonist
