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PANCE PREP > Pance endocrine round 2 8/15 > Flashcards

Pance endocrine round 2 8/15 Flashcards

1
Q

where is CRH produced and what effect does it have

A
  • hypothalamus

- produce more ACTH

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2
Q

what is the location of a primary disorder

A

at the gland level

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3
Q

what effect does an adrenal adeonoma have on cortisol

A

increase

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4
Q

anti thyrogloblin antobody what pathology

A

hashimotos

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5
Q

thyroid stimulating antibodies what pathology

A

graves

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6
Q

what are the three meds you give for a thyroid storm

A
  • PTU
  • Beta blocker
  • Glucocorticoids
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7
Q

thyroid brui think what

A

graves

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8
Q

what is the MC type of thyroid nodules

A

follicular adenoma

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9
Q

how often do you monitor a thyroid nodule with US

A

every 6- 12 months

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10
Q

what is the MC type of thyroid cancer

A

papillary

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11
Q

what is another name for Vit D

A

Calcitrol

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12
Q

what is the MC cause of hyperparathyroidism

A

patrathyrois adnenoma

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13
Q

what are the DTR with hypercalcemia

A

decreased

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14
Q

what are the DTR with hypothroid

A

decreased

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15
Q

what are the 2 MCC of hypoparathyroidism

A
  • surgery

- autoimmune

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16
Q

what are the 3 big physical exam signs of hyperparathyrod hormone

A
  • trousseau’s
  • chvosteks
  • Increased DTR
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17
Q

how do you tx hypoparathyroidism

A
  • Ca gluconate

- Vit D

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18
Q

what part of the EKG is effected by calcium

A

QT interval

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19
Q

hypocalcemia what effect of QT

A

long

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20
Q

3 tx for hypercalcemia

A
  • saline
  • fursemide
  • bisphosphenates
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21
Q

inc PTH and hypocalcemia what pathology

A

renal osteodystrophy

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22
Q
  • brown tumors

- salt pepper on X ray skull

A

renal osteodystrophy

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23
Q

how do you tx riskets

A
  • vit D (ergocalciferol)
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24
Q

what kidney disease has too much phosphate

A
  • renal osteodystrophy
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25
Q

how do you tx renal osteodystrophy 2

A
  • phosephate binders

- sevelamer

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26
Q

what gland produces ACTH

A

pituitary

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27
Q

what is the main cause of chronic adrenocortico insufficiency (primary: addisons, Secondary: pituitary)

A

Secondary: pituitary

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28
Q

what is the 2 main primary adrenocortico insufficiency (addiosns caused)

A
  • autoimune

- infection

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29
Q

what is the main secondary adrenocortico insufficiency

A
  • exogenous steroid use
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30
Q

what are the 4 metabolic disorders associated with addidosns

A

hyponatremia
hypoglycemia
hyperkalemia
metabolic acidosis

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31
Q

how do you tx primary adrenocortico insufficiency

A

hydrocortisone + fludrocortisone

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32
Q

how do you tx secondary adrenocortico insufficiency

A

hydrocotisone

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33
Q

what is the cause of addisons criss

A

abrupt withdrawl of glucocorticoids

34
Q

how do you tx adisosn crisis

A
  • IV fluids

- hydrocortisone, fludrocortisone

35
Q

what is the metabolic cause of cushings disease

A
  • Increased ACTH
36
Q

what is the potassium change with cushings

A
  • hypokalemia
37
Q

what is the cause of cushings disease

A
  • pituitary ademonia (secretes ACTH)
38
Q

what are the two main tests for cushings

A
  • 24 hr free cortisol in urine

- dexamethasone supression

39
Q

how do you tx a cortisol secereting ACTH tumor

A

ketoconazole

40
Q

how do you tx cushings diease

A
  • transphenodial surgery
41
Q

what are the two causes of hyperaldosteroneism

A
  • Conn syndrome

- renal artery stenosis

42
Q

catacholaime secreting tumor

A
  • Pheo
43
Q

what are the symptoms of pheo

A
  • palpitations
  • headache
  • excessive sweating
44
Q

how do you dx a pheo

A
  • 24 hr catacholamine collection
45
Q

how do you tx pheo

A
  • complete adrenalactomy
46
Q

what medication do not not start with when tx a pheo

A
  • beta blocker
47
Q

what hormones are secreted by the posterior puitary

A
  • ADH

- Oxytocin

48
Q

what hormone is a prolactin agonist

A
  • dopamine
49
Q

what two medications are dopamine agomist

A
  • cabergoline

- bromocriptine

50
Q

how do you tx acromegaly

A

octreotide

51
Q

what hormone is produced with somatotropinoma

A

growth hormone

52
Q

what are the two presentations of hyperprolactinemia

A
  • ammenorrhea

- galactorrhea

53
Q

what are the four medications that cause gyncomyastia

A

Spironalactone
cematadine
ketoconazole
finesteride

54
Q

what is the fasting glucose level for DM

A

126

55
Q

what are the two causes of DKA

A

infection

non compliance with insulin

56
Q

what element do you always give with DKA

A

postassium

57
Q

where is the problem with cushings disease

A

-pituitary

58
Q

what 2 meds are anti thyroid

A
  • MME

- PTU

59
Q

what are the 3 tx for graves

A
  • iodine
  • MME / PTU
  • Beta blockers
60
Q

what is the MCC of hyperparathyroidism

A

parathyroid adenoma

61
Q

what are the 3 P with MEN

A

parathyroid
pancreius
puititary

62
Q

what MEN is associated with pho

A
  • MEN 2
63
Q

3 tx for HYPERcalcemia

A
  • Fluids
  • fursemide
  • bisphosphenates
64
Q

1 tx for HYPOcalcemia

A
  • calcium gluconate
65
Q

what are the DTR with HYPERcalcemia

A

decreased DTR

66
Q

what is the DTR with GBS

A

decreased

67
Q

DTR with Hyperthyroid

A

increased

68
Q 
what are 
- trousseau's 
- chvosteks 
- Increased DTR
associated with
A

HYPOcalcemia

69
Q

Flat T waves

U waved

A

HYPOkalemia

70
Q

peaked T waved

A

HYPERkalemia

71
Q

what are the 3 tx for HYPER-Kalemia

A
  • calcium gluconate (stabilized the membrane)
  • Insulin
  • albuterol
72
Q

what adrenal insufficiency disorder still produces aldosterone and why

A

secondary because secondary is with the pituary and this means ACTH is not produced however aldosterone will be produced with the kidney

73
Q

aldoderone is what type of corticoid

A

mineral corticoid

74
Q

what is an eg of a mineral corticoid

A

fludrocortizone

75
Q

weight gain
hypokelemia
acanthosis nigracans

A

cushings

76
Q

what are the three endogenous causes for cushings

A
  • cushings disease (puitary adenoma)
  • ectopic ACTH
  • adrenal tumor
77
Q

test for cushings

A

dexamenthaosne supression

78
Q

test for adisons

A

ACTH stimulation

79
Q

how do you tx acromegaly 2 meds

A
  • bromocriptine

- Octreotide

80
Q

what are the two subjective reports for prolactin tumor

A
  • amenorrhea

- galactorrhea

81
Q

prolactin tumor tx 2

A

carbogaline

bromocriptine

82
Q

4 meds that cause gyncomaystia

A
  • spironalactone
  • Finesteride
  • cematatide
  • ketoconazole

PANCE PREP (27 decks)

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