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#‼️HISTOLOGY COPY > VIII - Skin > Flashcards

VIII - Skin Flashcards

1
Q

Outermost layer of integument, stratified squamous epithelial layer of ectodermal origin, devoid of blood vessels and consists of 4-5 layers

A

epidermis

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2
Q

Connective tissue layer of mesodermal origin below the epidermis and its basement membrane

A

dermis

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3
Q

Dermis: loose, comparatively cell-rich connective tissue, fills the hollows at the deep surface (dermal papillae) of the epidermis, capillaries are frequent, collagen fibers are finer

A

papillary layer

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4
Q

Dermis: appears denser and contains fewer cells, thick collagen fibers that aggregate into bundles

A

reticular layer

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5
Q

Layer of loose vascular connective tissue infiltrated by adipocytes

A

hypodermis

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6
Q

Skin: production of keratin protein, squamous epithelial cells

A

keratinocyte

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7
Q

Skin: important in formation of endogenous sunscreen, sound in basal layer and in hair follicles

A

melanocyte

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8
Q

Skin: epidermal dendritic cells, antigen presenting cells

A

Langerhan cells

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9
Q

Skin: serve as mechanoreceptors or a neuroendocrine function

A

Merkel cells

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10
Q

Disorder in which melanocytes are destroyed, autoimmune

A

Vitiligo

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11
Q

Disorder in which melanocytes are unable to synthesize melanin either due to abscence of tyrosinase activity or inability to take up tyrosine

A

Albinism

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12
Q

Skin Layers from most superficial

A

corneum, lucidum, granulosum, spinosum, basale

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13
Q

Skin Layers: superficial stratum layer consisting of 20-30 layers of dead, flat, anucleated and cornified/keratinized cells filled with keratin filaments (horny cells) embedded in a densematrix of proteins

A

Stratum Corneum

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14
Q

Skin Layers: spaces between cells are filled with lipids making a continuous membrane, protects against friction and water loss

A

Stratum Corneum

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15
Q

Skin Layers: 2-3 layers of transitional cells of flat eosinophilic anucleated cells, only found in regions of thick stratum corneum of palms and soles

A

Stratum Lucidum

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16
Q

Skin Layers: polygonal cells filled with basophilic keratohyaline granules, only 1 layer is seen in thin skin, multiple in thick skin

A

Stratum Granulosum

17
Q

Part of stratum granulosum that produces a lipid-rich impermeable layer around cells

A

lamellar granules

18
Q

Skin Layers: multilaminar layer of cuboidal-like cells that are bound together by numerous desmosomal junctions

A

Stratum Spinosum

19
Q

Antigen presenting cells in stratum spinosum, contains Birbeck granules

A

Langerhan cells

20
Q

Single layer of cuboidal to low columnar cells in contact with basement membrane, attached to the basal lamina via hemidesmosomes, mitotically active

A

Stratum Basale (Germinatum)

21
Q

Cells in the stratum basale with intense mitotic activity

A

melanocytes, Merkel cells

22
Q

Sensory Recetor Capsule: Merkel cells

A

unencapsulated

23
Q

Sensory Recetor Capsule: free nerve endings

A

unencapsulated

24
Q

Sensory Recetor Capsule: root hair plexuses

A

unencapsulated

25
Q

Sensory Recetor Capsule: Meissner corpuscles

A

encapsulated

26
Q

Sensory Recetor Capsule: lamellated (Pacinian) corpuscles

A

encapsulated

27
Q

Sensory Recetor Capsule: Krause end bulbs

A

encapsulated

28
Q

Sensory Recetor Capsule: Ruffini corpuscles

A

encapsulated

29
Q

Simple branched acinar holocrine grands, found in the dermis except in the palms and soles, lubricate hair and cornified layers of the skin to minimize dessication

A

sebaceous glands

30
Q

Sebaceous Glands: hairy areas

A

pilosebaceous unit

31
Q

Sebaceous Glands: glabrous skin

A

sweat pores

32
Q

Sudoriferous Glands

A

Sweat Glands

33
Q

Sweat Glands: coiled tubular glands, in most areas of the skin, opens in skin surface, clear, odorless (H2O, NaCl), active throughout life, body temperature regulation (cholinergic), emotional sweating (adrenergic)

A

eccrine, merocrine

34
Q

Sweat Glands: coiled tubular glands, axillary, areolar, anal, hair follicles, viscous, odorous, active at puberty, pheromones (adrenergic)

A

apocrine

35
Q

When apocrine sweat or sebaceous glands are occluded and infected

A

Hidradenitis Suppurativa

36
Q

Abnormal aggregation of cells that may be seen in squamous cell CA

A

keratin pearls

#‼️HISTOLOGY COPY (28 decks)

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