9.4 oxidative phosphorylation Flashcards
where is the ETC
inner membrane of the mitochondria
structure of ETC
most of the components of the chain are proteins
in multi protein complexes I-IV
-tightly bound to the proteins are prosthetic groups
prosthetic groups
nonprotein components essential for the catalytic functions of certain enzymes
what happens as they go down the chain
drop in free energy
–the components switch from reduced to oxidized as they take and pass on electrons from their neighbors
1:
NADH gives electrons to flavoprotein
2:
flavoprotein passes electrons to iron sulfur protein
3:
iron sulfur protein passes electrons to ubiquinone
Ubiquinone
AKA Coenzyme Q
only non protein in ETC
hydrophobic molecule
–mobile within the membrane rather than attached to a complex
4:
remaining electron carriers in the ETC are cytochromes with different heme groups
cytochromes
proteins that have a prosthetic group called a heme group
(iron atom that accepts and donates electrons)
like in HEMoglobin –except for electrons instead of O2
5:
last cytochrome
cyt a3 -> passes electrons to oxygen
6:
Oxygen is very electronegative
Oxygen atom picks up 2 hydrogen ions from the solution and forms water
FADH2
gives electrons to ETC at a lower level than NADH