OPATH/DX/RAD Flashcards

1
Q

One of the characteristics of the Brandywine type of dentinogenesis imperfecta (type III) includes:

A.	opacification of the dental pulp.
B.	periapical radiolucencies.
C.	severely affected primary teeth.
D.	associated with osteogenesis imperfecta.
A

B. PA RADIOLUCENCIES:

The Brandywine type (type III) of dentinogenesis imperfecta has features not seen in either type I or type II dentinogenesis imperfecta. These distinctive features include

  • multiple pulp exposures
  • periapical radiolucencies
  • variable radiographic appearance.

Radiographically, opacification of dental pulps is seen in type I and type II dentinogenesis imperfecta. This is due to continued deposition of abnormal dentin. In patients with type I, the primary teeth are more severely affected than their permanent teeth. Type I is a dentin abnormality that occurs in patients with concurrent osteogenesis imperfecta.

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2
Q

Which of the following is the MOST common non-odontogenic cyst?

	A.	Globulomaxillary cyst
	B.	Incisive canal cyst
	C.	Median palatal cyst
	D.	Nasoalveolar cyst
	E.	Nasolabial cyst
A

B. INCISIVE CANAL CYST:

The incisive canal cyst (median anterior maxillary cyst or nasopalatine cyst) is the most common non-odontogenic cyst. It is most commonly found in the incisive canal, as the name implies. Clinically, this cyst is asymptomatic.

  • The globulomaxillary cyst: (bw Max LI & C) is often asymptomatic; however, it can shift the interproximal contact points/areas of adjacent teeth toward the incisal edges, as roots of the maxillary lateral and cuspids are pushed apart.
  • The median palatal cyst is often located in the midline of the hard palate. Clinically, this cyst can produce a swelling.
  • The nasoalveolar cysts or nasolabial cysts are cysts found primarily in soft tissue and not in bone. Clinically, these cysts can cause swelling in the mucolabial fold.
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3
Q

Wickham striae are grayish white “lines” commonly seen in:

	A.	black hairy tongue.
	B.	Fordyce disease.
	C.	lichen planus.
	D.	nicotinic stomatitis.
	E.	white spongy nevus.
A

C. LICHEN PLANUS:

Lichen planus affects both the skin and oral mucous membranes. In addition to the characteristic violaceous lesions, which are usually etched with fine grayish white lines (Wickham striae), one may observe white scaly areas over a light pink base similar to psoriasis. Furthermore, lichen planus usually causes lesions to appear on the buccal mucosa, tongue, gingiva, and/or lips. Purplish papules may also be found on the skin. Patients may present asymptomatic or complain of pain in the affected areas.

  • Hairy tongue is a disorder that results in the elongation of filiform papillae of the tongue leading to the characteristic brown-black color of the dorsum of the tongue.
  • Fordyce disease causes buccal and/or labial mucosal lesions. This condition causes an aggregation of numerous small yellowish spots beneath the mucosal surface. They are ectopic sebaceous glands.
  • Nicotinic stomatitis is typically found on the hard palate of pipe smokers and is characterized by several white elevations with a central red area.
  • White sponge nevus is a congenital condition that alters the texture of the oral, vaginal, and/or anal mucosa. It causes painless lesions that are typically “pearly” white in appearance.
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4
Q

Which of the following MOST commonly occurs in postmenopausal women and results in a tingling sensation of the tongue?

	A.	Bullous lichen planus
	B.	Glossopharyngeal neuralgia
	C.	Orolingual paresthesia
	D.	Trigeminal neuralgia
	E.	White sponge nevus
A

C. OROLINGUAL PARESTHESIA:

Orolingual paresthesia causes a tingling or burning sensation of the tongue and oral mucosa. The tissue appears normal. This condition most commonly occurs in postmenopausal women.

  • Bullous lichen planus is a form of lichen planus in which necrosis of the basal cell layer is so severe in restricted foci that bullae form.
  • Glossopharyngeal neuralgia involves the ninth cranial nerve and results in the development of sharp shooting pain in the ear, pharynx, tonsils, and nasopharynx. It often occurs unilaterally with a trigger zone.
  • Trigeminal neuralgia is a major neuralgia involving the fifth cranial nerve yielding a searing, stabbing pain initiated by touching a trigger zone on the face. This condition is unilateral in most instances.
  • White sponge nevus appears on the oral mucosa with a thickened, spongy texture and opalescent hue.
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5
Q

Increasing kilovolts-peak will produce:

A.	more x-rays.
B.	lower x-ray quality.
C.	more "boiled off" electrons. D.	higher average energy electrons.
A

D. higher average energy electrons:

Increasing kilovolts-peak (kVp) increases the voltage difference from cathode to anode, resulting in more energetic electrons and thus higher-energy electrons. These high-energy x-rays are known as higher, not lower (choice B), quality x-rays. The kVp has no effect on the quantity of x-rays (choice A), which is determined only by the mA-s product (milliamps seconds). Electrons are boiled-off (choice C) in the generator.

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6
Q

All of the following are TRUE with respect to the microscopic examination of pleomorphic adenomas, EXCEPT:

A.	presence of  basophilic mucoid areas.
B.	presence of fibroblast-like spindle cells.
C.	presence of duct-like structures.
D.	presence of  plasmacytoid hyaline cells.
E.	presence of sheets of large, white epithelial cells.
A

E. presence of sheets of large, white epithelial cells: it’s small, dark epithelial cells*

Pleomorphic adenomas are the most common type of salivary tumors found in the oral cavity. These tumors comprise approximately 40% of intra-oral salivary gland tumors. Typical sites for pleomorphic adenomas are the palate, lip, and buccal glands. Microscopic exam typically reveals the presence of sheets of small, dark epithelial cells, not sheets of large, white epithelial cells. Common features of this tumor include the presence of basophilic mucoid areas; fibroblast-like spindle cells, duct-like structures, and plasmacytoid hyaline cells.

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7
Q

When an x-ray is generated, its energy is:

A.	directly proportional to its wavelength.
B.	inversely proportional to its frequency.
C.	directly proportional to its frequency.
D.	independent of wavelength and frequency.
A

C. directly proportional to its frequency:

Energy is directly related to frequency (high energy means high frequency) and inversely related to wavelength (high-energy and high-frequency waves have short wavelengths), which makes choices A, B, and D incorrect. The exact relationships are: energy = frequency X Planck’s constant, and speed = frequency X wavelength.

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8
Q

Which of the following correctly identifies the frequency in which salivary calculi appear in each respective salivary gland?

	A.	Parotid > submandibular > sublingual
	B.	Parotid > sublingual > submandibular
	C.	Sublingual > parotid > submandibular
	D.	Submandibular > parotid > sublingual
	E.	Submandibular > sublingual > parotid
A

D. Submandibular > parotid > sublingual:

Salivary calculi can be seen at any age; however, they peak in the third to sixth decade of life, with a male predominance. More than 80% of all stones occur in the submandibular gland.The remaining 20% of stones are found in the parotid gland; sublingual gland calculi are rarely found. In other words, the frequency in which salivary calculi appear in each respective salivary gland is as follows: submandibular > parotid > sublingual. Submandibular sialoliths, composed of calcium phosphate and organic matrix, are secondary to the more viscous and alkaline secretions of this gland as well as the anatomically “uphill” path of the Wharton duct.

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9
Q

Excessive x-ray exposure (>60 Gy) has been implicated in all of the following EXCEPT:

A.	pronounced radiation caries.
B.	trismus.
C.	osteoradionecrosis.
D.	hyposalivation.
A

D. HYPOSALIVATION:

Hyposalivation typically starts to occur in exposures ranging from 20 to 30 Gy. Excessive radiation exposure greater than 60 Gy has been implicated in pronounced radiation caries, trismus, and osteonecrosis, to name a few.

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10
Q

An elevated Bence-Jones protein level and multiple radiolucent areas in the mandible and skull are signs of which of the following types of cancer?

	A.	Hepatocellular
	B.	Myeloma
	C.	Ovarian
	D.	Pancreatic
	E.	Prostate
A

B. MYELOMA:

Tumor markers can be used to aid in the screening, diagnosing, and monitoring of an individual’s response to the treatment of the cancer. Furthermore, tumor markers can aid in the staging of an individual’s cancer. Bence-Jones proteins can be used to diagnose and determine the prognosis of multiple myeloma. Therefore, with the appearance of radiolucencies in the mandible and skull and Bence-Jones proteins in the blood, one should be able to conclude that the patient has multiple myeloma.

  • Hepatocellular carcinoma can be monitored with the detection of alpha-fetoprotein.
  • Ovarian cancer is monitored by the presence of CA 125; a high level of this tumor marker is closely related to a poor prognosis.
  • Pancreatic, colorectal, and gastric carcinoma can be followed by the presence of CA 19-9.
  • Prostate cancer is monitored by the presence of PSA (prostate-specific antigen).
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11
Q

The appearance of Forchheimer spots on the soft palate is MOST likely associated with:

	A.	Respiratory syncytial virus
	B.	Rhinovirus
	C.	Rosacea
	D.	Rubella
	E.	Rubeola
A

D. RUBELLA:

The prodromal illness for rubella, otherwise known as the German measles, is associated with the development of fever, headache, conjunctivitis, lymphadenopathy, and (occasionally) Forchheimer spots, which are small, red lesions found on the soft palate.

  • Respiratory syncytial virus (RSV) is associated with lower respiratory involvement, including pneumonia and bronchiolitis. RSV can also cause rhinorrhea, low-grade fever, and mild wheezing.
  • Rhinovirus often causes signs and symptoms of the common cold, such as rhinorrhea, fatigue, and mild temperature elevations.
  • Rosacea is a skin disease of the face in which the blood vessels enlarge, resulting in a constant “flushed” appearance of the cheeks and nose.
  • Rubeola , or measles, is a common disease contracted by children. This highly contagious disease has an incubation period of approximately 10 days followed by a prodromal period. During the prodromal illness, patients typically experience conjunctivitis, rhinorrhea, and a hacking cough. The appearance of Koplik spots (small, irregular, grayish white lesions on upper buccal mucosa) are considered pathognomonic. Before the appearance of the characteristic rash, there is an abrupt increase in the child’s temperature.
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12
Q

A 52-year-old male presents with multiple aphthous ulcers in the mouth, inflammatory ocular changes, and intestinal ulceration. Based on this information, the MOST likely diagnosis is:

	A.	Behç et syndrome.
	B.	Bell palsy.
	C.	Peutz-Jeghers syndrome.
	D.	tic douloureux.
	E.	white sponge nevus.
A

A. BECHET SYNDROME:

Behç et syndrome is characterized by recurring oral and genital ulcers and eye lesions. It is a multisystem disorder. Recurring oral ulcers occur in 90% of the patients and cannot be differentiated from RAS. Some have mild oral lesions others have deep scarring lesions characteristic of major RAS. Arthritis; intestinal ulceration; venous thrombosis; and renal, pulmonary, and CNS disease are other signs of the syndrome. Skin lesions are large and pustular.

  • Bell palsy is characterized with unilateral paresis of the facial nerve. It starts with slight pain around the one ear, followed by abrupt paralysis of the facial muscles on the affected side. The eye on the affected side stays open leading to corneal ulcerations, drooping of the corner of the mouth results in drooling, and masseter weakness leads to food retention in vestibule areas. This is the most common form of facial paralysis, and the onset of its associated signs and symptoms is relatively abrupt. Since this cranial nerve disorder results from an inflammation of the seventh cranial nerve, symptoms include paralysis of the facial muscles on the affected side. There is flattening of creases on the forehead, change of facial expression, and loss of taste sensations from the anterior two thirds of the tongue (when the chorda tympani is affected).
  • Peutz-Jeghers syndrome is a condition characterized by oral and external skin pigmentation as well as intestinal polyposis. The oral features often result in perioral and lip freckling and dark-brown spots on the lips, anterior tongue, and buccal mucosa. There is also freckling of the distal aspect of the fingers and toes.
  • The most common cranial neuralgia is trigeminal neuralgia, or tic douloureux. This condition is characterized by paroxysms of intense shooting, stabbing, and excruciating pain. The pain is usually unilateral, rarely lasts for more than a few seconds, and is precipitated by light touch/stimulation of the trigger zones present on skin/mucosa of the involved nerve branch. Shaving, showering, eating, talking, and even wind exposure can trigger the pain. Intraoral trigger zones can be very tricky to diagnose, as the stabbing pain can mimic the pain experienced with a cracked tooth.
  • White sponge nevus is a benign congenital condition that involves mucous membranes of the oral (most common), vaginal, nasal, and/or anal mucosa by producing painless lesions that are typically “pearly” white in appearance, although they can appear grayish white. it presents as bilateral, symmetric, and white soft spongy or velvety thick plaques on buccal mucosa. It is also seen on the ventral tongue, floor of mouth, labial mucosa, soft palate, and alveolar mucosa.
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13
Q

AIDS-related hairy leukoplakia is MOST commonly found on which of the following oral surfaces?

	A.	Buccal mucosa
	B.	Dorsum of the tongue
	C.	Hard palate
	D.	Lateral border of the tongue
	E.	Soft palate
A

D. LATERAL BORDER OF TONGUE:

Hairy leukoplakia is a benign epithelial hyperplasia associated with the Epstein-Barr virus (EBV). This oral disorder often precedes or accompanies “full-blown AIDS” and rarely occurs in individuals who are not HIV-infected. Hairy leukoplakia is usually found on the lateral borders of the tongue and rarely elsewhere in the oral mucosa. This condition is characterized by white lesions ranging from small flat areas to extensive and “hairy” areas.

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14
Q

Which of the following pairs of units measures the same thing?

A.	Gray, Sievert
B.	REM, Gray
C.	Roentgen, Sievert
D.	Rad, Gray
A

D. RAD, GRAY:

Rad and Gray both measure absorbed radiation. The measure of 1 Gray = 100 Rad. REM (choice B) and Sievert (choices A and C) both measure dose equivalents from differing types of radiation. Dose equivalent is the biological effect of radiation on tissues. The measure 1 Sievert = 100 REM. Roentgen and coul/kg measure the amount of radiation in air under standard, normalized conditions.

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15
Q

If a patient presents with lupus erythematosus-like eruptions on the buccal mucosa, this individual was MOST likely taking which of the following medications?

	A.	Diphenhydramine
	B.	Furosemide
	C.	Hydrocodone
	D.	Procainamide
	E.	Ranitidine
A

D. PROCAINAMIDE:

Lupus erythematosus is a systemic disorder of autoimmune etiology. The oral lesions typically associated with this disorder are often present on the buccal mucosa and are reddish lesions with slightly raised borders that surround a depressed center. Drugs like

  • hydralazine
  • methyldopa
  • phenytoin
  • procainamide

are known to produce these “lupus-like” eruptions.

  • Diphenhydramine, furosemide, and hydrocodone are all commonly associated with xerostomia.
  • Ranitidine does not commonly cause any oral side effects.
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16
Q

All of the following are known to predispose an individual to the development of oral squamous cell carcinoma, EXCEPT:

	A.	increasing age.
	B.	hepatitis.
	C.	tobacco usage.
	D.	chronic alcohol usage.
	E.	Plummer-Vinson syndrome.
A

B. HEPATITIS:

Hepatitis is an infectious disease primarily affecting the liver; this disorder does not predispose an individual to the development of squamous cell carcinoma. However, it dramatically increases the incidence of liver cancer. Oral squamous cell carcinoma accounts for 2% to 3% of all malignancies in the United States. The development of this disease is age-related, with a dramatic increase in incidence in those over the age of 40, and the male/female ratio is approximately 3:1. Other factors include tobacco usage, primarily; chronic alcohol usage; iron deficiency in Plummer-Vinson syndrome, and deficiencies of other vitamins. Evidence suggests that candidiasis and herpes simplex virus also increase the risk for oral squamous cell carcinoma.

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17
Q

A 3-year-old child presents with a sudden onset of fever, sore throat, and grayish white oropharyngeal lesions surrounded by red areola. If these vesicles were noted to enlarge and then ulcerate, the MOST likely diagnosis would be:

	A.	chickenpox.
	B.	herpangina.
	C.	herpes zoster.
	D.	infectious mononucleosis.
	E.	warts.
A

B. HERPANGINA:

Herpangina is a disease caused by the coxsackievirus A (and possibly the coxsackievirus B) and echovirus. This disorder is typically seen in children less than 4 years of age. Individuals with the disorder often present with a sudden onset of fever, sore throat, and grayish white oropharyngeal lesions surrounded by red areola. These lesions often enlarge and then ulcerate.

  • Chickenpox is caused by the varicella zoster virus and results in gingival and oral lesions that rupture to form shallow ulcers; the mucosa is very erythematous.
  • Herpes zoster is caused by a reactivation of the varicella zoster virus, leading to unilateral vesicular eruptions and ulcerations in a linear pattern following the sensory distribution of the trigeminal nerve or one of its branches.
  • Infectious mononucleosis is caused by the Epstein-Barr virus and often results in the development of fatigue, malaise, and numerous small oral ulcerations that often appear several days before the characteristic lymphadenopathy; there may also be some degree of gingival bleeding and petechiae at the junction of the hard and soft palate.
  • Warts may appear anywhere on the skin or in the oral cavity; the “classical” wart can be described as a papillary lesion with a thick white keratinized surface.
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18
Q

A patient presents with flushing and sweating of the involved side of the face during eating. If the patient’s condition is a possible complication of parotid tumor or a surgical procedure, the most likely diagnosis would be:

	A.	Auriculotemporal syndrome
	B.	Causalgia
	C.	Glossopharyngeal neuralgia
	D.	Mé niè re disease
	E.	Sphenopalatine neuralgia
A

A. AURICULOTEMPORAL SYNDROME:

Auriculotemporal syndrome is caused by damage of the auriculotemporal nerve and subsequent re-innervation of the sweat glands by the parasympathetic salivary fibers. This condition causes a flushing and sweating of the involved side of the face during eating. This condition is a possible complication of parotid tumor or a surgical procedure.

  • Causalgia is a rare severe pain syndrome that arises due to injury or sectioning of a peripheral sensory nerve. It can occur following difficult extraction. The burning pain can arise a few days to weeks after an extraction and is often evoked by thermal stimuli.
  • Glossopharyngeal neuralgia involves the ninth cranial nerve and results in the development of sharp shooting pain in the ear, pharynx, tonsils, and nasopharynx. It often occurs unilaterally and is associated with a trigger zone.
  • Ménière disease causes deafness, tinnitus, vertigo, and vomiting and often begins in middle age.
  • Sphenopalatine neuralgia or cluster headache causes unilateral spasms of intense pain in the region of the eyes, ears, and maxilla.
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19
Q

Current in a filament typically averages:

A.	70 kVp.
B.	5 to 20  kVp.
C.	120 V.
D.	5 to 20 mA.
A

D. 5 - 20 mA

The units used to measure current is milliamperes or mA. Typical current to a filament in the cathode is 5 to 20 mA.

Kilovoltage peak, or kVp, which is used to measure voltage. The typical kVp of the x-ray machine is about 70 to 90 in order to cause rapid electron acceleration, while 120 V is typically the voltage of the original power source.

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20
Q

Permissible film holders for x-rays of small children include:

A.	dentist, covered with lead apron.
B.	assistant, covered with lead apron.
C.	receptionist, covered with lead apron.
D.	parent, covered with lead apron.
E.	film holders are never acceptable even if covered by lead apron.
A

D. parent, covered with lead apron:

If a person is needed to hold a film for a child, the best choice is the parent. The parents should be thoroughly instructed before taking an x-ray, to avoid unnecessary re-takes. The parent is carefully shielded, often with two lead aprons(front and back), and a film badge monitor. Individuals who are occupationally exposed to radiation, such as dentists (choice A) and assistants (choice B), are not permitted to hold patients or to hold image receptors/films during exposure; nor should any individual, such as a receptionist (choice C), be regularly used for this service. It is recommended that, during the exposure, dental personnel who perform dental radiography stand behind a protective barrier. In situations in which dental personnel cannot stand behind a protective barrier, they must stand at least 6 feet away from the patient and the x-ray tube, not in the path of the primary beam. It is best to avoid human film holders and use film-holding instruments, if possible.

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21
Q

Which of the following is TRUE regarding higher quality x-ray beams?

A.	They are absorbed more by soft tissue.
B.	They scatter more.
C.	They produce less heat.
D.	They are absorbed more by soft tissue and scatter more.
A

B. X-rays tend to be absorbed or scattered. As an x-ray beam enters tissue, some x-rays are absorbed, whereas others bounce around and leave the tissue (scatter). Low-energy x-rays tend to be absorbed more (choices A and D). High-energy (hard beam, high quality) x-rays are not absorbed well. They pass through tissue and scatter more. Heat (choice C) is produced by the cathode and would not be a factor in the quality of x-ray beams.

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22
Q

Pseudoanodontia is synonymous with:

A.	absence of teeth.
B.	impaction of teeth.
C.	partial anodontia.
D.	false anodontia.
A

B. Impaction of teeth:

(pseudoanodontia) is common. It affects the mandibular third molars and maxillary cuspids most frequently. Impaction occurs because of obstruction from crowding, abnormal eruption path, or some other physical barrier. Absence of teeth is known as anodontia. It can be complete, with all teeth missing, or it can be partial anodontia, with one or several teeth missing. When the teeth have been exfoliated or extracted, it is termed false anodontia.

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23
Q

A patient presents with outgrowths that appear as aggressive pyogenic granulomas that do NOT metastasize but are of multicentric origin. If the patient has bluish/purplish lesions on the palate, buccal mucosa, and skin, which of the following is the correct diagnosis?

	A.	Fibroma
	B.	Hairy tongue
	C.	Kaposi sarcoma
	D.	Papilloma
	E.	Verruca vulgaris
A

C. Kaposi sarcoma:

is caused by a type of herpes virus. It is an “AIDS-defining illness” and occurs in late-stage HIV disease. It is a rare tumor that commonly appears as an aggressive pyogenic granuloma. It does not metastasize but is of multicentric origin. Patients typically present with bluish/purplish lesions of the palate, buccal mucosa, and skin. The tissue involved is the endothelial lining of blood vessels. Death from this condition most commonly occurs from gastrointestinal tract ulceration.

  • Fibroma is usually a smooth pink, firm, protruding mass often found on the labial mucosa and tongue.
  • Hairy tongue is a disorder that results from the elongation of filiform papillae of the tongue, leading to the characteristic brown-black color of the dorsum of the tongue.
  • A papilloma is a tumor that appears as a single, round, or oval entity 1 to 3 mm in diameter with a verrucous or cauliflower surface.
  • Verruca vulgaris are warts that resemble papillomas, except that they grow rapidly and result in multiple discrete lesions.
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24
Q

Which of the following is a neuralgia characterized by a “trigger zone” in the oropharynx or tonsillar fossa that manifests with pain in the ear, pharynx, nasopharynx, tonsil, and/or posterior tongue?

	A.	Bell palsy
	B.	Geniculate neuralgia
	C.	Glossopharyngeal neuralgia
	D.	Melkersson-Rosenthal syndrome
	E.	Trigeminal neuralgia
A

C. Glossopharyngeal neuralgia:

or ninth-nerve tic, is similar to the more well-known trigeminal neuralgia. The pain experienced by the patient is similar to that of trigeminal neuralgia but is confined to the distribution of the ninth cranial nerve; this neuralgia, characterized by a “trigger zone” in the oropharynx or tonsillar fossa, manifests with pain in the ear, pharynx, nasopharynx, tonsil and/or posterior tongue.

  • Bell palsy is the most common form of facial paralysis, and the onset of its associated signs and symptoms are relatively abrupt. Since this cranial nerve disorder results from an inflammation of the seventh cranial nerve, symptoms include paralysis of the facial muscles on the affected side and loss of taste sensation in the anterior two-thirds of the tongue.
  • Geniculate neuralgia is an exceedingly rare disorder with pain similar to that of trigeminal neuralgia but is primarily experienced deep in the ear.
  • Melkersson-Rosenthal syndrome is a cranial nerve syndrome that often presents with a triad of symptoms: recurrent facial paralysis, facial edema (particular labial), and plication of the tongue. However, not every patient presents with all components of the triad. Lip swelling is the constant dominant feature and usually begins prior to the facial paralysis.
  • The most striking disorder of the trigeminal nerve is a condition known as trigeminal neuralgia or tic douloureux. This condition is characterized by excruciating and frequently recurring paroxysms of pain in the lips, gums, cheek, or chin. Although the pain rarely lasts for more than a few seconds, spasmodic pain is typically so sharp and severe that the patient typically winces, hence, the name tic douloureux. One of the features of this disorder is unilateral facial pain with trigger zones. In other words, stimulation or movement of one of these trigger zones will initiate the paroxysm.
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25
Q

On a radiographic exam, what would a chevron artifact (sharp, angular lucency) indicate?

A.	Dentinal dysplasia
B.	Dentinogenesis imperfecta
C.	Internal resorption
D.	Pulp calcification
A

A. Dentinal dysplasia (DD): is a rare condition that affects dentin (autosomal-dominant condition).

  • Type I DD: has residual fragments of pulp tissue that appear typically as angular horizontal radiolucencies, called chevrons. The roots of these teeth are underdeveloped and and malformed. Because of this, patients may be more susceptible to periodontal disease.
  • Type II DD: affects the crowns and pulp chambers of teeth.
  • Type III DD: has pulp chambers and canals that are extremely large. Internal resorption of the dentin of pulpal walls is part of an inflammatory response to pulpal injury, sometimes with no apparent trigger. Resorption occurs as a result of the activation of osteoclasts or dentinoclasts on internal surfaces of the crown.
  • In dentinogenesis imperfecta (DI): opacification of dental pulps occurs, owing to continued deposition of abnormal dentin in types I and II.
  • Pulp calcification is common with increasing age, or it occurs for no apparent reason. Calcifications are either diffuse or nodular (pulp stones). Linear deposits are found in the root canals, parallel to the blood vessels. Pulp stones are usually found in the pulp chamber.
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26
Q

Which of the following viral diseases is LEAST likely to affect the gingiva?

	A.	Chicken pox
	B.	Herpangina
	C.	Herpes zoster
	D.	Primary HIV infection
	E.	Recurrent intraoral herpes simplex
A

B. Herpangina:

Although all of the viral diseases can affect the gingiva, herpangina (coxsackieviruses A and possibly B) primarily affects the oral mucosa, pharynx, and tongue. In this condition there is a sudden onset of fever, sore throat, and oropharyngeal vesicles. This condition often affects children under 4 years of age during the summer months.

  • Chickenpox primarily affects the gingiva and oral mucosa.
  • Herpes zoster (reactivation of varicella zoster virus) primarily affects the cheeks, tongue, gingiva, or palate.
  • Primary HIV infection causes acute gingivitis and oropharyngeal ulceration.
  • Recurrent intraoral herpes simplex results primarily in gingivitis and small vesicles on the oral mucosa.
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27
Q

All of the following characteristics are seen in Ewing sarcoma, EXCEPT:

A.	onion-skin appearance of bone.
B.	occurrence between 5 and 30 years old.
C.	predilection for the ramus of the mandible.
D.	tumors consisting of undifferentiated small cells alternating with areas of cartilage.
A

D. tumors consisting of undifferentiated small cells alternating with areas of cartilage:

In mesenchymal chondrosarcoma, the undifferentiated small cell proliferation resembles Ewing sarcoma. The alternating areas of cartilage found by the small cells distinguishes the diseases.

Ewing sarcoma has:

  • moth-eaten radiolucency and erosion of the cortex with expansion.
  • the variable periosteum looks like onion skin.
  • Ninety percent of Ewing sarcoma occurs between 5 and 30 years. The younger a patient is diagnosed (under 10 years of age), the poorer the prognosis.
  • When the jaws are involved, there is a predilection for the ramus of the mandible, with a few cases reported in the maxilla.
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28
Q

The appearance of a “strawberry” or “raspberry” tongue is MOST commonly associated with which of the following disorders?

	A.	Iron-deficiency anemia
	B.	Pellagra
	C.	Scarlet fever
	D.	Severe cyanocobalamin deficiency
	E.	Syphilis
A

C. SCARLET FEVER:

The appearance of a “strawberry” or “raspberry” tongue is most commonly associated with patients diagnosed with scarlet fever. The appearance of the tongue is caused by hypertrophy of the fungiform papillae as well as changes in the filiform papillae. Patients who present with “bald” tongue generally have one of the following disorders: iron-deficiency anemia; pellagra; severe cyanocobalamin deficiency, otherwise known as pernicious anemia, or syphilis.

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29
Q

If a patient is diagnosed with the MOST common type of metastatic tumor found in the jaw, which of the following is the correct diagnosis?

	A.	Adenocarcinoma
	B.	Basal cell carcinoma
	C.	Bowen disease
	D.	Malignant melanoma
	E.	Squamous-cell carcinoma
A

A. Adenocarcinoma:

is the most common type of metastatic tumor found in the jaw. In general, adenocarcinoma refers to a group of malignant neoplasms of epithelial cells that appear in glandlike patterns.

  • Basal cell carcinoma is caused by ultraviolet radiation. This is a slow-growing neoplasm that rarely metastasizes.
  • Bowen disease is a form of cancer in situ that is caused by arsenical therapy.
  • Malignant melanoma is one of the most deadly of all malignancies; however, it is rarely found in the oral cavity.
  • Squamous-cell carcinoma is the most common malignancy of the oral cavity, but it is more often primary, rather than metastatic, in the oral cavity.
30
Q

A 4-month-old infant presents with a sudden onset of swelling of the face and thorax and is notably more hyperactive. The swelling around the mandible gives the appearance of a tumor. If radiographic examination of the mandible reveals the appearance of new bone, the MOST likely diagnosis is:

	A.	Caffey syndrome.
	B.	Down syndrome.
	C.	Fordyces disease.
	D.	Melkersson-Rosenthal syndrome.
	E.	Papillon-Lefevre syndrome.
A

A. Caffey syndrome:

or infantile cortical hyperostosis, is a condition that involves the mandible and may even give the appearance of a tumor This condition usually occurs before 6 months of age and is characterized by a sudden onset of swelling of the face, thorax, or extremities along with hyperirritability, a fluctuating fever, and radiographic evidence of “new” bone formation under the swollen areas.

  • Down syndrome is a congenital abnormality that results in the delayed eruption of teeth. Furthermore, some of the primary teeth may remain until the age of 14. There is also a high incidence of gingival inflammation and alveolar bone loss.
  • Fordyce disease results in buccal and/or labial mucosal lesions; there is an aggregation of small yellowish spots (ectopic sebaceous glands) beneath the mucosal surface.
  • Melkersson-Rosenthal syndrome is a cranial nerve syndrome that often presents with a triad of symptoms: recurrent facial paralysis, facial edema (particular labial), and plication of the tongue. Not all patients present with all components of the triad. Lip swelling is the constant dominant feature and usually begins prior to the facial paralysis.
  • Papillon-Lefevre syndrome is an autoimmune recessive disorder consisting of hyperkeratosis of the palms and soles as well as destruction of the supporting tissues of both dentitions.
31
Q

The gland and arch MOST damaged by radiation are the:

A.	submandibular and maxilla.
B.	submandibular and mandible.
C.	parotid and maxilla.
D.	parotid and mandible.
A

D. PAROTID & MANDIBLE:

The parotid gland is the most sensitive salivary gland in terms of damage from x-rays due to its high concentration of serous acinar cells in comparison to the submandibular gland. It undergoes fibrosis and adiposis, and xerostomia usually results. The effect on the bone tissue in the two arches is predictable. The damage to the mandible is worse, primarily due to its poorer circulation and the greater difficulty in repairing damage. Bone breakdown from infection, following irradiation, is referred to as osteoradionecrosis.

32
Q

A patient who presents with painful grayish white collapsed vesicles with a peripheral erythematous zone on the upper oral mucous membranes is MOST likely to be diagnosed with:

	A.	acute leukemia.
	B.	gonorrhea.
	C.	histoplasmosis.
	D.	mucous membrane pemphigoid.
	E.	white sponge nevus.
A

D. MMP:

Mucous membrane pemphigoid, as the name implies, occurs primarily on the mucous membranes of the oral cavity but can involve the eyes, urethra, vagina, and rectum. It typically produces painful grayish white collapsed vesicles, or bullae, with a peripheral erythematous zone. The gingival lesions often desquamate, leaving an ulcerated area.

  • Acute leukemia is a neoplastic disorder known to cause gingival swelling and superficial ulcerations followed by hyperplasia of the gingiva with extensive necrosis and hemorrhage. Deep ulcerations may occur elsewhere in the oral cavity; however, other types of lesions seen in patients with acute leukemia typically appear after gingival complications have occurred.
  • Gonorrhea is a sexually transmitted disease that commonly produces oral lesions, which appear at the site of inoculation or secondarily by hematogenous spread from a primary focus. This disease is known to produce oral burning or itching sensations, followed by acute pain on eating. The tonsils are frequently involved, and the saliva develops an increased viscosity as well as a fetid odor. Submaxillary lymphadenopathy with fever is seen in severe cases.
  • Histoplasmosis can affect any area of the mouth and can cause numerous small nodules, which may ulcerate; fever and malaise are usually present.
  • White sponge nevus is a congenital condition that alters the texture of the oral, vaginal, and/or anal mucosa. These painless lesions are typically “pearly” white in appearance, although they can appear grayish white. This disorder is often familial in nature and results from a thickening of the mucosa.
33
Q

A patient complains of pain, paresthesia of the lip, and mobile teeth. The patient reports a mass in his jaw that is growing in size. Radiographs reveal moth-eaten, poorly marginated destruction of bone. This patient has:

A.	multiple myeloma.
B.	Burkitt lymphoma.
C.	Paget disease.
D.	solitary plasmacytoma of bone.
A

B. Burkitt lymphoma:

is a high-grade non-Hodgkin lymphoma that is endemic in Africa and occurs sporadically in North America. The usual signs associated with jaw lesions are an expanding intraoral mass and mobility of teeth. Pain and paresthesia are occasionally present. There is a moth-eaten appearance in the affected area.

  • Multiple myeloma has multiple, “punched-out” but noncorticated radiolucent areas.
  • Paget disease radiographically shows a haphazard patchy pattern termed “cotton-wool.”
  • Solitary plasmacytoma presents with swelling, pain, and pathologic fracture. Radiographically, it is a well-defined lytic lesion that may be multilocular. A significant number of these patients progress to multiple myeloma.
34
Q

A 13-year-old patient presents with gingival inflammation. Upon examination, the patient is noted to have several primary teeth and a high incidence of alveolar bone loss. Based on this information, which of the following is the correct diagnosis?

	A.	Caffey syndrome
	B.	Down syndrome
	C.	Fordyce disease
	D.	Melkersson-Rosenthal syndrome
	E.	Papillon-Lefè vre syndrome
A

B. Down syndrome:

is a congenital abnormality (trisomy 21). Oral manifestations include:

  • delayed eruption of teeth
  • prolonged retention of primary teeth (up to age 14)
  • bifid uvula
  • submucous cleft and cleft palates
  • malocclusion
  • large and fissured tongue
  • cracked lips
  • There is also a high incidence of gingival inflammation and alveolar bone loss.

Caffey syndrome, or infantile cortical hyperostosis: is a condition that involves the mandible and may even give the appearance of a tumor. This condition usually occurs before 6 months of age and is characterized by a sudden onset of swelling of the face, thorax, or extremities along with hyperirritability, a fluctuating fever, and radiographic evidence of “new” bone formation under the swollen areas.

Fordyce disease: results in buccal and/or labial mucosal lesions. The lesions result from the aggregation of numerous small yellowish spots (ectopic sebaceous glands) beneath the mucosal surface. It is not truly a disease.

Melkersson-Rosenthal syndrome: is a cranial nerve syndrome that often presents with a triad of symptoms: recurrent facial paralysis, facial edema (particular labial), and plication of the tongue. However, not all patients present with all components of the triad. Lip swelling is the constant dominant feature and usually begins prior to the facial paralysis.

Paplllon-Lefè vre syndrome: is an autoimmune recessive disorder characterized by hyperkeratosis of the palms and soles and destruction of the supporting tissues of both dentitions.

35
Q

The intensity of x-rays hitting a film at a distance of 12 inches is recorded. If the distance is reduced to 4 inches, the intensity will now be:

A.	3 times as much.
B.	12 times as much.
C.	9 times as much.
D.	1/9 as much.
A

C. 9 times as much:

Intensity refers to the number of photons hitting a given area of object or film. As the x-ray source gets closer to an object, the intensity of the beam increases, and it decreases as the x-ray source goes further away. If the distance goes from 12 inches to 4 inches (distance is now 1/3), the intensity will be the inverse square, or 9 times the intensity (3 squared equals 9).

36
Q

X-rays are produced as:

A.	electrons leave the cathode.
B.	electrons accelerate from the anode.
C.	electrons leave the filament.
D.	electrons strike the anode.
A

D. electrons strike the anode:

X-rays are produced from decelerating electrons at the anode. In the generator, electrons are boiled off the hot filament and accelerated from cathode (-) to anode (+). When they hit the anode, the electrons decelerate rapidly, giving off radiation energy (producing high temperatures in the process). Note that they do not become x-rays. X-rays are energy given off.

37
Q

High-quality (hard) beams are produced by adjusting:

A.	collimation and mA.
B.	mA and kVp.
C.	filtration and mA.
D.	filtration and kVp.
A

D. Filtration & kVp:

Quality is related to energy level. kVp controls the quality of radiation. Increase in kVp increases the potential difference between the cathode and anode, which results in increase in energy of each electron that strikes the target. The greater the potential difference, the less time is required for the electrons to travel from the cathode to the anode. This results in a better conversion of electron energy into x-ray photons. Increase in kVp also leads to an increase in the mean energy of the photons, maximum energy of the photons, and also the number of photons. The penetrability of x-ray photons depends on their energy. The higher the energy of the x-ray photons, the greater the penetrability, whereas, the lower the energy, the greater the probability of x-ray photons being absorbed. The radiation that is harmful to a patient is the radiation that is absorbed. X-ray photons of different energies are present in the x-ray beam. Only (high-energy) photons that can penetrate through anatomic structures and reach the image receptor (usually film) are useful for diagnostic imaging. Photons with low energy (long wavelength) contribute to patient exposure and do not reach the film. To reduce patient dose (exposure), the less-penetrating photons should be removed. This can be achieved by placing an aluminum filter in the path of the beam. The aluminum filter removes the lower-energy (long waves) photons. The filter has lesser effect on the higher-energy photons that penetrate the film. The amount of filtration required for a particular x-ray machine is calculated by measuring the kVp and inherent filtration of the tube and its housing. Inherent filtration is achieved through the glass wall of the x-ray tube, the insulating oil that surrounds many dental tubes, and the barrier material that prevents the oil from escaping through the x-ray port. Total filtration = inherent filtration plus external filtration (aluminum disks). Governmental regulations require the total filtration in the path of a dental x-ray beam to be equal to the equivalent of 1.5 mm of aluminum to 70 kVp, and 2.5 mm of aluminum for all higher voltages (i.e., above 70 kVp). With increase in mA (choices A, B, and C), more power is applied to the filament, which heats up and releases more electrons (increases the thermionic emission) and thus the x-ray photons. A direct relationship exists between mA and radiation output. Thus, mA controls the quantity of the radiation. Collimation controls and restricts the size and shape of the beam, thus protecting the adjacent structures against radiation exposure and damage. A collimator is a metallic barrier with an aperture in the middle that reduces the size and shape of the x-ray beam. The round collimator is a thick plate of radiopaque material (usually lead) with a circular opening centered over the port in the x-ray head through which the x-ray beam emerges. Rectangular collimators further reduce the beam size and make it slightly larger than the x-ray film. Few film-holding instruments also provide rectangular collimation. Use of collimation also aids in improving image quality.

38
Q

Half-value layer is a term used in the measurement of:

A.	aperture size.
B.	dosimetry.
C.	filtration.
D.	collimation.
A

C. filtration:

Often, the total filtration of an equipment is assessed by evaluating the quality of the x-ray beam, also denominated penetrability or penetrating energy, numerically characterized by the half-value layer (HVL). The HVL (also half-value thickness) is the amount of absorbing material needed to decrease the x-ray intensity by 50%. HVL is measured in millimeters of aluminum.

39
Q

Which statement about collimation or filtration is TRUE?

A.	Collimation uses aluminum, while filtration uses lead.
B.	Filtration includes restriction of aperture (window) size and shape.
C.	Collimation reduces x-ray leakage and scatter.
D.	Inherent collimation is achieved through the glass wall of the x-ray tube, the insulating oil, and the barrier material.
A

C. Collimation reduces x-ray leakage and scatter:

X-ray photons of different energies are present in the x-ray beam. Only (high-energy) photons that can penetrate through anatomic structures and reach the image receptor (usually film) are useful for diagnostic imaging. Photons with low energy (long wavelength) contribute to patient exposure and do not reach the film.

To reduce patient dose (exposure), the less-penetrating photons should be removed. This can be achieved by placing an ALUMINUM FILTER in the path of the beam. The aluminum filter removes the lower-energy (long-wave) photons. The filter has lesser effect on the higher-energy photons that penetrate the film. The amount of filtration required for a particular x-ray machine is calculated by measuring the kVp and inherent filtration of the tube and its housing. Inherent filtration is achieved through the glass wall of the x-ray tube, the insulating oil that surrounds many dental tubes, and the barrier material that prevents the oil from escaping through the x-ray port. Total filtration = inherent filtration plus external filtration (aluminum disks). Governmental regulations require the total filtration in the path of a dental x-ray beam to be equal to the equivalent of 1.5 mm of aluminum to 70 kVp and 2.5 mm of aluminum for all higher voltages. (i.e., above 70 kVp).

Collimation controls and restricts the size and shape of the beam, thus protects the adjacent structures against radiation exposure and damage by reducing x-ray scatter and leakage. A collimator is a metallic barrier with an aperture in the middle that reduces the size and shape of the x-ray beam; filtration does not accomplish this. The round collimator is a thick plate of radiopaque material (usually lead) with a circular opening centered over the port in the x-ray head through which the x-ray beam emerges. Rectangular collimators further reduces the beam size and makes it slightly larger than the x-ray film. Few film-holding instruments also provide rectangular collimation. Use of collimation also aids in improving image quality.

40
Q

Glossodynia is commonly associated with all of the following EXCEPT:

	A.	candidiasis.
	B.	diabetes.
	C.	diuretic usage.
	D.	periodontal disease.
	E.	tobacco usage.
A

D. Perio disease:

Glossodynia (sometimes called “ burning mouth syndrome” ) is defined as a burning and pain of the tongue; it may occur with or without glossitis, which is an inflammation of the tongue. Glossodynia is commonly associated with diseases that can directly affect the tongue, such as candidiasis, or “ thrush.” This fungal infection most commonly affects infants, the elderly, or people with compromised immune systems. It may also present with fatigue, digestive problems, UTIs, yeast infections, sinus problems, or joint pain. Since xerostomia (chronic dry mouth) can also lead to glossodynia, diabetic patients and those taking diuretics will commonly experience glossodynia secondary to the osmotic or drug induced diuresis (water loss), respectively, leading to dry mouth. Tobacco usage is also known to cause glossodynia, since it directly irritates the tongue, mucosa, and other oral structures.

Periodontal disease is not commonly associated with glossodynia, since this disease does not commonly affect the tongue.

41
Q

In the dental x-ray unit, electrons travel from the:

A.	anode to the cathode.
B.	anode to the focal spot.
C.	target to the filament.
D.	filament to the anode.
A

D. filament to the anode:

X-rays are generated in an x-ray tube consisting of a cathode (negative electrical charge) and an anode (positive electrical charge). The cathode consists of a small coil of wire (a filament). When current is applied to the filament, it emits electrons. Electrons are attracted and accelerated toward the anode. Electrons travel from the cathode toward the anode. As the electrons collide and interact with the anode target, an increased amount of energy is produced, 1% of which is in the form of x-radiation; 99% appears as heat. The focal spot is a very small area on the surface of the anode, where radiation is produced. The dimensions of the electron beam arriving from the cathode determine the dimensions of the focal spot, usually ranging from usually range from 0.1 mm to 2 mm. The focal spot is approximately rectangular in most of the x-ray tubes. X-ray tubes are designed to have specific focal spot sizes: the smaller the focal spot, the less blur and the better the detail of the image. Large focal spots have a greater heat-dissipating capacity.

42
Q

Which of the following is a tumor primarily found in infancy and consists of connective tissue stroma containing foci of pigmented cells with pale nuclei that surround small spaces with groups of nonpigmented cells?

	A.	Adenomatoid odontogenic tumor
	B.	Ameloblastic tumor
	C.	Calcifying epithelial odontogenic tumor
	D.	Melanotic neuroectodermal jaw tumor
	E.	Squamous odontogenic tumor
A

D. Melanotic neuroectodermal jaw tumor:
is a tumor found primarily in infancy; it consists of:
- connective tissue stroma containing foci of pigmented cells with pale nuclei that surround small spaces with groups of nonpigmented cells.

Adenomatoid odontogenic tumors (AOT):

  • primarily found in the teens or third decade
  • higher incidence in women
  • primarily found in the anterior maxilla
  • consists of whorls of small, dark epithelial cells with amorphous or crystalline calcifications and microcysts lined by ameloblast-like columnar epithelium.

Ameloblastic tumors:

  • rare tumors found primarily in teenagers
  • possess epithelium resembling ameloblasts; however, these tumors surround satellite reticula.

Calcifying epithelial odontogenic tumor (CEOT):

  • rare tumor that resembles a poorly differentiated carcinoma
  • contains sheets of variably sized squamous cells typically with well-differentiated intracellular bridges
  • nuclei are often pleomorphic, large, and hyperchromic, resembling a carcinoma.

Squamous odontogenic tumor (SOT):
- rare tumor consisting of multiple “islands” of well-differentiated squamous cells in connective tissue stroma

43
Q

Which of the following is MOST likely to result in the development of a fluid-filled space between the crown of the tooth and reduced enamel epithelium?

	A.	Ameloblastoma
	B.	Craniopharyngioma
	C.	Dentigerous cyst
	D.	Lateral periodontal cyst
	E.	Primordial cyst
A

C. DENTIGEROUS CYST:

A dentigerous cyst or follicular cyst is caused by a change in the reduced enamel epithelium after complete formation of the crown of the tooth. This is likely to result in the development of a fluid-filled space between the crown of the tooth and reduced enamel epithelium. This type of cyst is most commonly found in the mandibular third molar and maxillary cuspid area.

  • Ameloblastoma: is an ectodermal odontogenic tumor that occurs primarily in the mandible and often expands the bone, producing asymmetry of the face.
  • Craniopharyngioma: is a pituitary tumor derived from remnants of the Rathke pouch and resembles an ameloblastoma.
  • Lateral periodontal cyst: resembles a primordial cyst of the supernumerary tooth with a predilection for the mandibular cuspid and bicuspid area.
  • Primordial cyst: is caused by cystic degeneration of stellate reticulum of enamel. It may show keratin or prekeratin formation. In patients with this condition, a cyst is often found instead of a tooth.
44
Q

All of the following changes occurring in a pigmented lesion on the buccal mucosa support the diagnosis that this lesion is transforming into a melanoma EXCEPT

	A.	absence of pain.
	B.	development of satellite lesions.
	C.	INCREASE in size.
	D.	color variegation.
	E.	ulceration.
A

A. absence of pain:

Malignant melanoma is a rare neoplasm of the oral cavity, the oral mucosa is primarily involved in fewer than 1% of melanomas. However, it is important to distinguish this lesion from other pigmented lesions that may occur in the oral cavity. When the lesion is 1.0 mm to 1.0 cm or larger or there is significant swelling, pain, paresthesia or anesthesia, tooth mobility or spontaneous exfoliation, root resorption, and/or bone loss or bleeding associated with the lesion, melanomas should be suspected. The most frequent location of these tumors is the palate and maxillary gingiva (approximately 80%) of patients, but buccal mucosa, mandibular gingiva, and tongue lesions are also identified. Metastatic melanoma most frequently affects the mandible, tongue, and buccal mucosa. Lesions are usually largely macular, but nodular and even pedunculated lesions occur. Erythema is observed when the lesions are inflamed. Long-standing lesions may present the following features: elevation, color variegation, ulceration, and satellite lesions that may have the appearance of physiologic pigment.

45
Q

A 57-year-old male with asthma and osteoarthritis presents with a confirmed oral fungal infection that produces a number of white lesions in the mouth. When the “white” portion of these lesions are scraped away, there is a red, erythematous, bleeding area. Based on this information, these lesions are MOST likely caused by which of the following medications?

	A.	Albuterol inhalation
	B.	Budesonide inhalation
	C.	Ipratropium inhalation
	D.	Theophylline oral tablets
	E.	Verapamil oral tablets
A

B. Budesonide inhalation:

The patient in question has signs and symptoms suggestive of oral candidiasis. Oral Candidiasis is a fungal infection of the oral cavity. When its characteristic “white” lesions are scraped away, there is typically a red, erythematous, bleeding area. Corticosteroids, especially inhaled corticosteroids such as budesonide, are frequently associated with the development of oral candidiasis. These agents decrease the patient’s ability to fight the onset of oral infections, such as those caused by Candida albicans. To prevent the appearance of these oral fungal infections, patients should be instructed to wash their mouths after using an inhaled corticosteroid. The products listed in the other answer choices are not associated with the development of oral candidiasis.

Albuterol is a beta-receptor agonist used primarily for the treatment of asthma.

Ipratropium is an anticholinergic agent used for the treatment of asthma and other respiratory disorders.

Theophylline oral tablets are xanthine derivatives used primarily for the treatment of asthma.

Verapamil oral tablets are used for the treatment of both hypertension and cardiac arrhythmias.

46
Q

Which of the following dental findings are consistent with Paget disease?

	A.	Chronic hyperplastic pulpitis
	B.	Hypercementosis
	C.	Pericoronitis
	D.	Pyogenic granuloma
	E.	Widening of the periodontal ligament space
A

B. HYPERCEMENTOSIS:

Paget disease is a chronic bone disease that involves connective tissue proliferation, which destroys old bone and forms “new” bone. This process ultimately leads to enlarged bones as well as hypercementosis. Clinically, this disease is easily recognizable, as the maxilla is enlarged bilaterally and in all directions.

Chronic hyperplastic pulpitis is a condition that results from pulpal infection. It leads to the proliferation of granulation tissue.

Pericoronitis is an acute infection involving the gingival tissue around a tooth that has not fully erupted.

Pyogenic granuloma is a distinct proliferative clinical entity originating as a local irritation that occurs at any age and most frequently on the gingiva.

Widening of the periodontal ligament space is NOT associated with Paget disease.

47
Q

Chronic inflammation at the apex of a nonvital tooth results in:

A.	periapical (radicular) cyst.
B.	periapical abscess.
C.	cellulitis.
D.	cavernous sinus thrombosis.
A

A. PERIAPICAL (radicular) CYST:

Chronic periapical inflammation of a nonvital tooth results in a periapical granuloma that, in turn, can result in a periapical cyst.

Acute periapical inflammation may result in a periapical abscess that may spread and lead to cellulitis or cavernous sinus thrombosis. In cellulitis, the acute inflammation spreads diffusely through the tissue. Cellulitis of the submandibular space is called “Ludwig angina.” If the infection involves a major blood vessel, the situation becomes dangerous. Cavernous sinus thrombosis is an emergency situation that is often fatal.

48
Q

A disease is known to produce oral burning or itching sensations, followed by acute pain on eating. If the tonsils are involved, and the saliva develops increases viscosity as well as a fetid odor, the MOSTlikely diagnosis is:

	A.	acute leukemia.
	B.	gonorrhea.
	C.	histoplasmosis.
	D.	mucous membrane pemphigoid.
	E.	white sponge nevus.
A

B. Gonorrhea:

is a sexually transmitted disease that commonly produces oral lesions that appear at the site of the inoculation or secondarily by hematogenous spread from a primary focus. (The most common infections sites include the urethra, rectum, throat, or cervix.) This may not show any symptoms; however, some patients experience oral burning or itching sensations, followed by acute pain on eating or swallowing. The tonsils are frequently involved, and the saliva develops an increased viscosity as well as a fetid odor. Clinically, this may look similar to strep throat. Submaxillary lymphadenopathy with fever is seen in severe cases. This condition is treatable, and can resolve within days to weeks of treatment.

Acute leukemia is a neoplastic disorder known to cause gingival swelling and superficial ulcerations followed by hyperplasia of the gingiva with extensive necrosis and hemorrhage. Deep ulcerations may occur elsewhere in the oral cavity; however, other types of lesions seen in patients with acute leukemia typically appear after gingival complications have occurred.

Histoplasmosis is an infection caused by inhaling the spores from a fungus commonly found in bird or bat feces. It can affect any area of the mouth and can cause numerous small nodules, which may ulcerate; fever and malaise are usually present.

Mucous membrane pemphigoid (MMP) is a rare, autoimmune disorder. As the name implies, MMP occurs primarily on the oral mucous membranes. It typically produces painful grayish white collapsed vesicles or bullae with a peripheral erythematous zone.

White sponge nevus (sometimes called Cannon disease) is a congenital condition that alters the texture of the oral, vaginal, and/or anal mucosa. These painless lesions are typically “pearly” white in appearance, although they can appear grayish white; this disorder is often familial in nature and results from a thickening of the mucosa.

49
Q

A patient diagnosed with chickenpox is noted to have small vesicles on the oral mucosa that rupture to form shallow ulcers. This patient’s condition is caused by which of the following?

	A.	Epstein-Barr virus
	B.	Herpes simplex virus
	C.	Papillomavirus
	D.	Type A coxsackieviruses
	E.	Varicella zoster virus
A

E. VZV:

Chickenpox is a childhood disease. The causative virus of chickenpox is varicella zoster virus. The oral manifestations of chickenpox include the development of small vesicles on the oral mucosa that rupture to form shallow ulcers. These oral lesions do not cause diagnostic, symptomatic or management problems. Herpes zoster (HZ) is a viral disease caused by a reactivation of the varicella zoster virus. HZ has a prodromal period of 2 to 4 days when shooting pain, paresthesia, burning, and tenderness appear along the course of the nerve. Oral lesions resemble the lesions seen in HSV infection. Diagnosis is based on history of pain and unilateral nature and segmental distribution of lesions. Epstein-Barr virus (EBV) (choice A) is the causative virus in infectious mononucleosis. EBV, also known as human herpesvirus 4, is a member of the herpesvirus family. It is one of the most common human viruses. EBV spreads most commonly through bodily fluids, primarily saliva. Infection of adolescents and young adults with EBV often results in infectious mononucleosis with fever, lymphadenopathy, sore throat, and splenomegaly. Additional signs and symptoms can include fatigue, headache, hepatomegaly, and rash. EBV is also associated with a number of malignancies including Hodgkin disease, B cell lymphomas, and nasopharyngeal carcinoma. Herpes simplex virus (choice B) results in the development of primary acute herpetic gingivostomatitis, primary gingivostomatitis, and recurrent intraoral herpes simplex virus infections. Acute herpetic gingivostomatitis is associated with generalized symptoms of fever, headache, malaise, nausea, and vomiting followed by (important diagnostic criteria) the development of oral vesicles; round, shallow symmetric oral ulcers; and acute marginal gingivitis typically associated with labial lesions, which often crust. The intraoral lesions quickly ulcerate and become very painful. The vesicles quickly rupture, leaving ulcers that are present on all portions of the mucosa. Several lesions coalesce, forming large, irregular lesions. The entire gingiva is edematous and inflamed (Important diagnostic criteria). Submandibular and cervical lymph nodes are tender and enlarged. Papillomavirus (choice C) is associated with the development of warts (verruca vulgaris) and oral squamous lesions. The term verruca vulgaris is used when a crop of lesions develop. Squamous papillomas occur in the 3rd through 5th decades and are commonly seen as isolated palatal lesions. When they occur on keratinized surfaces (such as lips, alveolar gingiva, or palate) they are wart-like and well-keratinized with a narrow pedicle. They appear soft and redder on nonkeratinized surfaces. The three clinical types infections of the oral region caused by group A coxsackievirus include herpangina; hand, foot, and mouth disease; and acute lymphonodular pharyngitis. They also cause a rare mumps-like form of parotitis. Clinical manifestation of herpangina include generalized symptoms of fever, malaise, anorexia, sore throat, dysphagia, and (occasionally) sore mouth. Lesions begin as punctate macules and evolve into papules and vesicles involving the posterior pharynx, tonsillar pillars, and soft palate. Within 1 to 2 days, vesicles rupture and form ulcers. It should not be confused with HSV infection. It is milder, occurs in epidemic, involves posterior portions of oral mucosa (diagnostic), lesions are smaller, and does not cause generalized acute gingivitis. With this self-limiting disease, supportive care is advised. Hand, foot, and mouth disease is known to cause fever, malaise, and headache as well as vesicles that are painful and lead to shallow ulcerations in the oral mucosa. Non-pruritic papules, macules, and vesicles develop on the palms and soles. This disease is caused by type A coxsackieviruses and involves more extensive oral lesions than those of herpangina. Lesions on hard palate, tongue, and buccal mucosa are common. Treatment is supportive. In acute lymphonodular pharyngitis, the distribution of lesions same as herpangina. However, yellow-white nodules appear that do not evolve to vesicles or ulcers. With this self-limiting disease, supportive care is advised.

50
Q

A patient presents with a disorder that results in an abnormal increase in the number of circulating red blood cells and hemoglobin. If the oral manifestations of this disease cause spontaneous gingival bleeding with minimal but persistent oozing, and the gingiva are described as swollen or congested and “spongy-soft,” theMOST likely diagnosis would be:

	A.	acute leukemia.
	B.	irritative fibromatosis.
	C.	neutropenia.
	D.	polycythemia.
	E.	primary syphilis.
A

D. Polycythemia:

is a disorder that results in an abnormal increase in the number of circulating RBCs and hemoglobin; the oral manifestations of this disease are commonly associated with spontaneous gingival bleeding with minimal but persistent oozing, and the gingiva are often described as swollen or congested and “spongy-soft.”

Acute leukemia: neoplastic disorder known to cause gingival swelling and superficial ulcerations followed by hyperplasia of the gingiva with extensive necrosis and hemorrhage.

Irritative fibromatosis: condition that begins as a generalized inflammatory response of the marginal and interdental gingival tissue. It then progresses to a bullous mass that obscures the major portion of the crowns of the teeth.

  • Leukopenic diseases: such as neutropenia and agranulocytosis, result in the development of a variety of oral manifestations that are primarily due to an increased predisposition to infection from the normal oral flora. Ulcerations of the buccal mucous membranes, tonsils, soft palate, and pharynx are commonly found, characteristically with no inflammation.
  • Primary syphilis causes the development of small papules that form a large painless ulcer (chancre) with indurated borders.
51
Q

A middle-aged African American woman presents to the office. She complains of pain and swelling in the mandible. Radiographs reveal a diffuse lesion affecting a large part of the jaw. There are radiolucent areas in association with sclerotic masses. This patient has:

A.	focal sclerosing osteomyelitis.
B.	acute osteomyelitis.
C.	diffuse sclerosing osteomyelitis.
D.	Garre osteomyelitis.
A

C. Diffuse sclerosing osteomyelitis:

is seen in any age, sex, or race but tends to occur most frequently in middle-aged African American females. The characteristic sclerotic masses are composed of dense bone.

Focal sclerosing osteomyelitis: typically found in young adults. Patients are usually asymptomatic. Radiographs show the lesion as either uniformly opaque, with a peripheral radiolucency in an opaque center, the reverse, or lobulated.

Acute inflammation of the bone or bacteremia causes acute osteomyelitis. Most cases of acute osteomyelitis are infectious. Patients usually complain of pain. Unless the inflammatory process has been present for more than 1 week, radiographic evidence is not present. With time, diffuse radiolucent changes begin to appear.

Garre osteomyelitis: often results from a periapical abscess in a mandibular molar. Radiographs reveal a central mottled, predominantly radiolucent lesion.

52
Q

Which of the following is the MOST common cause of pharyngitis?

	A.	Bacteria
	B.	Fungi
	C.	Parasites
	D.	Medications
	E.	Viruses
A

E. VIRUSES:

Pharyngitis is an infection or irritation of the pharynx and tonsils. The incidence peaks between ages 4 and 7 years but can occur throughout a person’s life. Seasonal variation occurs, with a higher incidence in the winter months. The most common cause of pharyngitis is viral. Rhinovirus and adenovirus are the most common, but the Epstein-Barr virus, influenza virus, herpes simplex virus, and coronavirus can also cause the development of this condition.

Bacteria are the second leading cause of pharyngitis. The most common bacteria associated with pharyngitis are Streptococcus and Staphylococcus species, as well as Haemophilus, Mycoplasma, Neisseria, and Corynebacterium.

Fungi and parasites generally do not cause pharyngitis except in immunocompromised patients. Medications are rarely associated with the development of pharyngitis.

53
Q

Which of the following conditions is primarily caused by non-hereditary factors?

	A.	Amelogenesis imperfecta
	B.	Dentinogenesis imperfecta
	C.	Enamel hypoplasia
	D.	Microdontia
	E.	"Yellow" hypoplasia
A

C. Enamel hypoplasia:

is an abnormality of enamel development due to the interference with normal matrix formation leading to enamel surface defects, irregularities, and color changes. Although this disorder is primarily caused by deficiency of vitamins A, C, and D; calcium; and phosphorus, other factors such as local, systemic, or hereditary disturbances may contribute. Amelogenesis imperfecta (choice A) is a hereditary anomaly that produces enamel defects in both the primary and permanent dentitions; there are several types of this disorder, such as hypomaturation- and hypoplastic-types. Dentinogenesis imperfecta (choice B) is another hereditary disorder similar to amelogenesis imperfecta; it causes opalescent dentin, transparent enamel, and dentin hypoplasia. Microdontia (choice D) is a hereditary disorder that causes teeth to be much smaller than normal teeth. “Yellow” hypoplasia (choice E) is a common hypoplasia that is hereditary in nature. All parts of the tooth, including the root, are discolored yellow to yellow-orange.

54
Q

Increasing current to the filament:

A.	reduces its temperature.
B.	increases the energy of each electron.
C.	increases the speed of electrons hitting the filament.
D.	increases the number of electrons emitted.
A

D. increases the number of electrons emitted:

With increase in mA, or current, more power is applied to the filament, which heats up (choice A) and releases more electrons, or increases the thermionic emission, that collide with the target to produce more x-ray photons. A linear relationship exists between mA and radiation output. The quantity of radiation produced (mAs) is expressed as the product of time and tube current. Thus, mA controls the quantity of radiation. Increases in current do not affect the quality (energy) of the x-rays formed. kVp (choice B) controls the quality of radiation. An increase in kVp increases the potential difference between the cathode and anode, which results in an increase in energy of each electron that strikes the target. The greater the potential difference, the lesser time is required for the electrons to travel from the cathode to the anode (choice C). This results in a better conversion of electron energy into x-ray photons. An increase in kVp also leads to an increase in the mean and maximum energy of the photons and also increases the number of photons. The penetrability of x-ray photons depends on their energy. The higher the energy of the x-ray photons, the greater is the penetrability, whereas the lower the energy, the greater is the probability of x-ray photons being absorbed. The radiation that is harmful to a patient is the radiation that is absorbed.

55
Q

A patient presents with parotid gland enlargement, dry mouth, keratoconjunctivitis and dysphagia. If blood test reveals the presence of Rh factor, one should suspect a diagnosis of:

	A.	polyarteritis nodosa.
	B.	Reiter syndrome.
	C.	rheumatoid arthritis.
	D.	Sjö gren syndrome.
	E.	systemic lupus erythematosus.
A

D. Sjögren syndrome:

is an autoimmune disorder associated with a chronic dysfunction of the exocrine glands. Individuals with this disorder often present with keratoconjunctivitis, parotid gland enlargement, dry mouth leading to difficulty in speaking and swallowing, loss of taste, and pleuritis. A positive rheumatoid factor (Rh factor) is seen in over 70% of all patients with this disorder.

Polyarteritis nodosa is a disorder characterized by focal or segmental lesions of blood vessels. The pathological hallmark of this disease is acute necrotizing inflammation of the arterial media with extensive inflammatory cell infiltration of all layers of the vessels and surrounding tissue. Patients also present with fever, hypertension, abdominal pain, and elevated sedimentation rate.

Reiter syndrome is the leading cause of arthritis in young adults, especially men. This disorder is commonly associated with a recent onset of arthritis, conjunctivitis, and urethritis. Another common finding in this condition is keratoderma blennorrhagicum, which typically presents as an erythematous pustular, scaly and plaque-like set of lesions on the palms of the hands and soles of the feet.

Rheumatoid arthritis is a progressive disorder of unknown etiology. The characteristic feature of this disorder is the persistent inflammatory synovitis, usually involving the peripheral joints in a symmetric manner. Although a positive Rh factor is seen in many individuals with this disorder, keratoconjunctivitis and parotid gland enlargement are not commonly seen.

Systemic lupus erythematosus is associated with arthralgias, fatigue, malaise, fever, and weight loss as well as the malar “butterfly” rash that is an erythematous rash raised over the cheeks and bridge of the nose. Various renal and nervous system complications are also associated with this disorder.

56
Q

Juvenile periodontitis is INITIALLY characterized by which of the following?

	A.	Tooth loss
	B.	Marginal gingivitis
	C.	Shifting of the teeth
	D.	Toothache
	E.	Ulcerative gingivitis
A

C. Shifting of teeth:

Juvenile periodontitis (periodontosis) (aggressive periodontitis) is a rapidly destructive disease of the alveolar bone. This disorder commences with pubescence and can result in up to 75% alveolar bone loss in less than 5 years. The initial clinical picture is unremarkable except for the abrupt finding of a periodontal pocket upon probing the “normal-looking” gingiva. As the disease progresses, one would initially see a sudden shifting of the teeth, which eventually progresses to tooth loss. In the latter stages of the disease, one may see marginal gingivitis, and the patient may experience some degree of tooth pain. Ulcerative gingivitis is an unlikely complication of this disease. The most commonly affected teeth are incisors and first molars.

57
Q

Which of the following is the primary site of MOST metastatic carcinomas found in the jaw?

	A.	Breast
	B.	Lung
	C.	Kidney
	D.	Thyroid
	E.	Colon
A

A. Breast:

Metastatic carcinoma is related to a history of primary cancer elsewhere in the body. A primary carcinoma from any anatomic site may metastasize to the jaw bone. The mandible is the most frequently involved. Radiographic evaluation often varies and can be osteolytic or osteogenic, having multiple lesions or only a single one. The primary sites of metastatic carcinomas found in the jaw (listed based on the frequency of occurrence) are as follows :
breast > lung > kidney > thyroid > prostate > colon

58
Q

All of the following are characteristics of Papillon-Lefè vre syndrome (PLS) EXCEPT one. Which one is this EXCEPTION?

A.	Severe periodontal attachment loss and bone loss
B.	Hyperkeratotic lesions
C.	Treatment is effective if diagnosed early
D.	Autosomal-recessive genetic disease
A

C. Treatment is effective if diagnosed early:

No treatment has been shown to be effective for PLS. Vital submersion of the roots (vital root banking) of the teeth may stabilize alveolar bone height and contour, and prognosis may improve for a lifetime of complete denture use. Severe periodontal attachment loss and bone loss around primary and permanent teeth and hyperkeratotic lesions of the hands and feet are characteristic of the disease. Teeth may be lost within 2 to 3 years after eruption. The disease is an autosomal-recessive genetic disease.

59
Q

A patient presents with a white lesion with a definite erythematous content on the buccal mucosa. If this lesion cannot be removed by rubbing the mucosal surface, one should suspect:

	A.	candidiasis.
	B.	erythroplakia.
	C.	leukoedema.
	D.	papilloma.
	E.	Peutz-Jeghers syndrome.
A

B. Erythroplakia:

is a disorder of the oropharynx that is initially characterized by a white lesion that cannot be removed by rubbing the mucosal surface. When this lesion has a definite erythematous content, the most likely cause is squamous cell carcinoma. An important characteristic of this lesion is the erythematous component, which is often indicative of either dysplasia or carcinoma. Carcinoma is seen in the majority of individuals diagnosed with erythroplakia.

Candidiasis is a fungal infection that commonly occurs in the oral cavity; if the “white” portion of the lesion can be scraped away revealing a red, erythematous area, a diagnosis of candidiasis can probably be made.

Leukoedema is an asymptomatic condition that can affect all of the peripheral soft tissues of the mouth. The clinical appearance is a light gray or grayish white smooth or slightly wrinkled mucosal surface.

A papilloma is a benign tumor seen as isolated palatal lesions. It also often arises in the common wall between the nose and the maxillary sinus. When it occurs on keratinized surfaces (such as lips, alveolar gingiva, or palate) it is wart-like and well-keratinized with a narrow pedicle. It appears soft and redder on nonkeratinized surfaces. Peutz-Jeghers syndrome is a condition characterized by oral and external skin pigmentation as well as intestinal polyposis. The oral features often result in dark-brown spots on the lips and buccal mucosa. There is a characteristic distribution of the pigment around the lips, nose, eyes, and hands.

60
Q

Radiographic examination of a “cyst” in a patient reveals the presence of an inverted teardrop-shaped radiolucency between the roots of the lateral incisor and cuspid. Based on this information, which of the following is the correct diagnosis?

	A.	Globulomaxillary cyst
	B.	Median anterior maxillary cyst
	C.	Nasopalatine
	D.	Median palatal cyst
	E.	Nasolabial cyst
A

A. Globulomaxillary cyst:

is often asymptomatic; however, it can shift the contact point of adjacent teeth toward the incisal edges as roots of the maxillary lateral and cuspids are pushed apart. Radiographic examination of the cyst in a patient often reveals the presence of an inverted teardrop-shaped radiolucency between the roots of the lateral incisor and cuspid. The incisive canal cyst (median anterior maxillary cyst) (choice B) or nasopalatine cyst (choice C) (alternative names for the same condition) is the most common non-odontogenic cyst. Radiographic examination of this cyst often reveals the presence of a round or heart-shaped radiolucency in the midline, near the apices of the maxillary central incisors. The median palatal cyst (choice D) is often located in the midline of the hard palate. Radiographic examination of the cyst typically reveals the presence of a radiolucent area seen opposite the premolar teeth on palatal film. The nasoalveolar cyst or nasolabial cyst (choice E) is a midline cyst found primarily in soft tissue. It is not detected on radiographs, unless the bone is secondarily affected.

61
Q

A patient presents with an asymmetric painless enlargement of the jaw. If an oral examination reveals a smooth expansion of the alveolar ridge as well as the adjacent bone, the MOST likely diagnosis is:

	A.	angioedema.
	B.	Caffey syndrome.
	C.	fibrous dysplasia.
	D.	osteoporosis.
	E.	pericoronitis.
A

C. Fibrous dysplasia:

is a disease associated with intraosseous connective tissue proliferation with new bone formation. The most common complaint is a painless enlargement or asymmetry of the face or jaws; this enlargement is usually an insidious process and present in the patient for many years. Oral examination reveals a smooth expansion of the alveolar ridge and adjacent bone; the mucosa is often normal and the teeth involved are often displaced.

Angioedema is a well-demarcated localized edema involving the deeper layers of the skin including the subcutaneous tissues. This condition can affect the eyelids, lips, tongue, glottis, and/or larynx. The affected tissue usually remains “normal in color” although it can be pale to slightly red.

Caffey syndrome, or infantile cortical hyperostosis, is a condition that involves the mandible and may even give the appearance of a tumor. This condition is characterized by a sudden onset of swelling of the face, thorax, or extremities along with hyperirritability, a fluctuating fever, and radiographic evidence of “new” bone formation under the swollen areas.

Although osteoporosis is a common metabolic bone disease, the skull and jaws are not dramatically affected.

Pericoronitis is an acute infection involving the gingival tissue around a tooth that has not fully erupted.

62
Q

If a patient presents with necrotizing, ragged mucosal ulceration with no apparent inflammatory response, the MOST likely diagnosis is:

	A.	acute leukemia.
	B.	infectious mononucleosis.
	C.	neutropenia.
	D.	polycythemia.
	E.	primary syphilis.
A

C. Neutropenia:

Leukopenic diseases, such as neutropenia and agranulocytosis, result in the development of oral manifestations that are primarily due to an increased predisposition to infection from the normal oral flora. Ulcerations of the buccal mucous membranes, tonsils, soft palate, and pharynx are commonly found, characteristically with NO inflammation. The reason why these necrotic ulcerative lesions typically present with no inflammation is that there are no neutrophils to combat the infection in the oral cavity.

Acute leukemia is a neoplastic disorder known to cause gingival swelling and superficial ulcerations, followed by hyperplasia of the gingiva with extensive necrosis and hemorrhage.

Infectious mononucleosis often results in the development of fatigue, malaise, and numerous small oral ulcerations that appear several days before the characteristic lymphadenopathy.

Polycythemia is a disorder that results in an abnormal increase in the number of circulating red blood cells and hemoglobin; the oral manifestations of this disease are commonly associated with spontaneous gingival bleeding with minimal but persistent oozing, and the gingiva are often described as swollen or congested and “spongy-soft.”

Primary syphilis causes the development of small papules, developing into a large painless ulcers (chancres) with indurated borders.

63
Q

The eruption of which permanent tooth, together with the primary dentition, is usually the first sign of the mixed dentition stage?

	A.	Mandibular lateral
	B.	Maxillary central
	C.	Mandibular first molar
	D.	Maxillary first molar
	E.	Mandibular first premolar
A

C. Md 1st molar:

The term “mixed dentition” refers to the dental development stage at which primary teeth are present with some permanent teeth. In chronological age, it often lasts from about age 6 to about age 12 or 13. The loss of the last primary tooth, usually the maxillary primary canine (or maxillary primary second molar), signals the end of the mixed dentition stage. The beginning of the stage should therefore start when the first permanent tooth joins the primary teeth already present. In a majority of cases, the first permanent tooth to appear, at about age 6, is the permanent mandibular first molar. Another, less likely, candidate is the mandibular central incisor, often appearing at age 6. Choices A, B, D, and E are therefore incorrect.

64
Q

A 60-year-old woman presents to the dental office complaining of INCREASED spacing between her once-contacted teeth. She discloses that she has vertigo and headaches. Radiographs reveal hypercementosis of tooth roots, loss of lamina dura, and obliteration of the periodontal ligament as well as a generalized, patchy radiopaque pattern in the bone. This patient is suffering from:

A.	hyperparathyroidism.
B.	hypophosphatasia.
C.	multiple myeloma.
D.	Paget disease.
A

D. Paget disease (also known asosteitis deformans):

is a chronic, slowly progressive disease in osseous tissues with unknown etiology. Early neurological symptoms include headache, dizziness, deafness, tinnitus, vertigo, and pain due to radicular compression. The maxilla is affected approximately twice as often as the mandible. This disease interferes with the body’s normal process of replacing old bone with new bone. Over time, the bones may become enlarged (leading to spacing between the teeth), brittle, weak, or misshapen. This makes the body more prone to fractures or injury complications. Other areas that are commonly affected by Paget disease include the pelvis, spine, and legs. Hypercementosis of tooth roots, loss of lamina dura, and obliteration of the periodontal ligament are also characteristics of Paget disease. A classic radiographic finding in the later stages of Paget disease is a haphazard arrangement of newly formed bone, providing a patchy radiopaque pattern termed “cotton wool.” Men are more commonly affected than women, and the risk increases with age (40 to 60+).

Patients with hyperparathyroidism may complain of pain. Severe osseous changes result from significant bone demineralization, with fibrous replacement producing radiolucencies (unilocular or multilocular).

Hypophosphatasia is a deficiency of alkaline phosphatase. Characteristics of the disease include alveolar bone loss with predisposition for the anterior portion of the mandible or maxilla and hypoplasia or aplasia of cementum over the root surface. It is most commonly diagnosed in babies or children, and it affects the Caucasian population more than any other group.

Multiple myeloma is commonly seen in patients over 50 years of age, and it is most common in African American males. Involvement of the jaws may produce pain. Multiple myeloma is a plasma cell neoplasm with predilection for the nasopharynx, nasal cavity, and tonsils. Tumors have also been reported in the gingiva, palate, floor of the mouth, and tongue. Its typical radiographic appearance is multiple, sharply “punched-out” but noncorticated radiolucent areas of bone destruction in the jaws.

65
Q

Diabetic patients, in relation to non-diabetics, are at a much higher risk for developing all of the following, EXCEPT:

	A.	alveolar bone resorption.
	B.	candidiasis.
	C.	erythroplakia.
	D.	gingivitis.
	E.	xerostomia
A

C. Erythroplakia:

is a disorder of the oropharynx initially characterized by a white lesion that cannot be removed by rubbing the mucosal surface. When this lesion has a definite erythematous content, the most likely cause is squamous cell carcinoma; the incidence of the disorder is not increased in diabetic patients. Diabetes often makes itself known first in the oral cavity. Alveolar bone resorption is directly related to the duration and severity of the diabetes. As blood glucose levels increase, the glucose levels in the saliva and gingival fluid increase, and the oral microbial population generally increases, leading to an increased incidence of candidiasis and gingivitis. The initial symptom of diabetes is often xerostomia, or dry mouth, which is caused by an excessive loss of fluid secondary to the associated osmotic diuresis.

66
Q

A 43-year-old female presents with several light gray and grayish white slightly wrinkled lesions on her oral mucosal surface. If these lesions are otherwise asymptomatic, one would expect a diagnosis of:

	A.	Fordyce disease.
	B.	lichen planus.
	C.	leukoedema.
	D.	nicotinic stomatitis.
	E.	white sponge nevus.
A

C. Leukoedema:

is an asymptomatic condition that can affect all the peripheral soft tissues of the mouth. The mucosal surface appears light gray or grayish white that may be smooth or slightly wrinkled.

Fordyce disease results in buccal and/or labial mucosal lesions. In this disorder, there is an aggregation of numerous small yellowish spots (ectopic sebaceous glands) beneath the mucosal surface.

Lichen planus is a disorder that usually appears on the buccal mucosa, tongue, gingiva, and/or lips. The clinical features of this disorder include striae (Wickham striae), white plaques, red areas, and ulcers in the mouth. Purplish papules may also be found on the skin. Patients may be asymptomatic or complain of pain in the affected areas.

Nicotinic stomatitis is typically found on the hard palate of pipe smokers and is characterized by several white elevations with a central red area.

White sponge nevus is a congenital condition that alters the texture of the oral, vaginal, and/or anal mucosa. These painless lesions are typically “pearly” white in appearance, although they can appear grayish white. White sponge nevus is a disorder that is often familial in nature and results from a thickening of the mucosa.

67
Q

Macroglossia is MOST commonly encountered in which of the following disorders?

	A.	Addison disease
	B.	Behç et syndrome
	C.	Down syndrome
	D.	Infectious mononucleosis
	E.	White sponge nevus
A

C. Down Syndrome:

Macroglossia is an enlarged tongue that may be part of a syndrome found in developmental conditions, such as Down syndrome; it may be due to a tumor (hemangioma, or lymphangioma), metabolic diseases (such as primary amyloidosis), or endocrine disturbances (such as acromegaly or cretinism).

Addison disease is a disorder caused by adrenal insufficiency. This disorder causes bluish black to dark-brown (pigmentation) blotches or spots primarily on the buccal mucosa.

Behçet syndrome is associated with the development of multiple aphthous ulcers in the mouth; inflammatory ocular changes, ulcerative lesions on the genitalia, and inflammatory bowel and CNS disease.

Infectious mononucleosis often results in the development of fatigue, malaise, and numerous small oral ulcerations that often appear several days before the development of lymphadenopathy.

White sponge nevus is a congenital condition that alters the texture of the oral, vaginal, and/or anal mucosa by producing painless lesions that are typically pearly white in appearance, although they can appear grayish white.

68
Q

A 47-year-old male presents with unilateral facial paralysis and unilateral vesicular eruptions in the oral mucosa and external ear. Based on this information, the MOST logical diagnosis would be:

	A.	Bell palsy.
	B.	glossopharyngeal neuralgia.
	C.	Melkersson-Rosenthal syndrome.
	D.	Ramsay Hunt syndrome.
	E.	trigeminal neuralgia.
A

D. Ramsay Hunt syndrome:

is believed to be caused by a herpes zoster infiltration of the geniculate ganglion. This condition is characterized by Bell palsy and unilateral vesicle formation in the oral mucosa and external ear.

Bell palsy is characterized by unilateral paresis of the facial nerve. It starts with slight pain around the one ear followed by abrupt paralysis of the facial muscles on the affected side. The eye on the affected side stays open leading to corneal ulcerations, drooping of the corner of the mouth results in drooling, and masseter weakness leads to food retention in vestibule areas. There is flattening of creases on the forehead, change of facial expression, and loss of taste sensations from the anterior two thirds of the tongue (when the chorda tympani is affected).

In glossopharyngeal neuralgia, paroxysmal pain is similar to but less intense than that of trigeminal neuralgia. The pain experienced by the patient and trigger zones follow the distribution of the ninth cranial nerve (pharynx, posterior tongue, ear, and infra-auricular retromandibular area). Pain may be triggered in the pharyngeal mucosa due to chewing, talking, or swallowing.

Melkersson-Rosenthal syndrome: rare neurological disorder characterized by

  • recurring facial paralysis
  • swelling of the face and lips (usually the upper lip)
  • development of folds and furrows in the tongue. It is seen in childhood or early adolescence.
  • After recurrent episodes, swelling may persist and increase, eventually becoming permanent.
  • lip may become hard, cracked, and fissured with a reddish brown discoloration.

The most common cranial neuralgia is trigeminal neuralgia: This condition is characterized by paroxysms of intense shooting, stabbing, and excruciating pain. The pain is usually unilateral, rarely lasts for more than a few seconds, and is precipitated by light touch/stimulation of the trigger zones present on skin/mucosa of the involved nerve branch. Shaving, showering, eating, talking, and even wind exposure can trigger the pain. Intraoral trigger zones can be very tricky to diagnose, as the stabbing pain can mimic the pain experienced with a cracked tooth.

69
Q

Which of the following statements about contrast is TRUE?

A.	Short scale contrast involves many shades of gray.
B.	High kVp yields high contrast.
C.	Low contrast is made up of mostly black and white.
D.	Contrast is controlled by adjusting mA per second.
E.	Short scale contrast is considered high contrast.
A

E. Short scale contrast is considered high contrast:

Contrast in a radiograph permits visibility of recorded details.
Contrast is the different shades of density in a radiograph. Contrast is affected by the kVp, type of film, processing solution, and tissues being irradiated. When a minimum number of gradations of gray between the blacks and whites is seen on a radiograph, it is described as short-scale contrast (high contrast). Lower kVp decrease the scale of contrast (high contrast). At low kVp, the penetration of tissues is lesser; therefore, the density difference of adjacent areas on the radiograph will be small. When an increased number of gradations of gray between the blacks and whites is seen on a radiograph, it is described as long-scale contrast (low contrast). Higher kVp increases the scale of contrast (low contrast). At high kVp, the penetration of tissues is greater; therefore, the density difference of adjacent areas on the radiograph will be greater.

70
Q

With respect to dental caries, which of the following is the MOST cariogenic?

	A.	Fructose
	B.	Dextrose
	C.	Glycogen
	D.	Lactose
	E.	Sucrose
A

E. Sucrose:

Streptococcus mutans is the chief causative bacterium responsible for dental caries. Sucrose is considered the most cariogenic because it is not only fermented by oral bacteria, but it is also a substrate for the synthesis of extracellular (EPS) and intracellular (IPS) polysaccharides. Sucrose-facilitated low pH environment causes a change in the resident plaque microflora to a more cariogenic one, EPS facilitates transformation in the composition of the biofilm matrix. Also, the biofilm formed in association with sucrose has lesser concentrations of Ca, Pi, and F, which are important for de- and remineralization of enamel and dentin.

It should be noted that all sugars, including fructose and dextrose are cariogenic. However, sucrose is the most cariogenic.

Glycogen is a polysaccharide that is the principal storage form of glucose (Glc) in animal and human cells.

Lactose is rarely consumed in pure form; it is usually present in dairy products that seem to have low cariogenic potential and may even have a protective effect.