vaccins and cold chain Flashcards

1
Q

classification of vaccine

A
live
killed
toxoids
proteinaceous
polysaccharide
glucoconjugate
recombinant
combinant
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2
Q

live vaccines list

A
BCG
OPV(ora polio vaccine)
measles
mumps
rubella
yellow fever
varecella chicken pox
typhoral
japanese encephilitis live
h1n1 live
rotavirus
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3
Q

killed vaccines list

A
pertussis
rabies
injectable polio vaccine
hep a
menengiococcal
Kyasanur Forest disease (kfd)
japanese encephilitis killed
h1n1 killed
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4
Q

toxoids vaccins list

A

dipyheria

tetaanus

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5
Q

combinate vaccine list

A

MMR,MR
pentavalent
dpt

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6
Q

recombinant vaccine

A

hep b

hpv(human papilloma virus)

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7
Q

glucocongugate vaccine list

A

pneumococcal
menengiococcal
hib(hemophylis influenza b)

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8
Q

polysaccharide vaccine

A

typh im - vi. (typhoid intra muscular)
pneumococcal
menengiococcal
hib

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9
Q

proteinacious vaccine

A

acellular pertusis

anthrax

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10
Q

what is clostrum

A

is the first form of milk produced by the mammary glands of mammals

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11
Q

component of national immunization schedule

A

universal immunization program 1985

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12
Q

UIP program is the part of

A

RCH program under National Health Mission

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13
Q

when does immunization start in india and stop

A

at birth, 16 years

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14
Q

what is the word “attenuation” in vaccine

A

reduction of virulence, maintainence of antigenicity(antigenic nature of vaccine)

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15
Q

which live vaccine as an exception can be given in pregnency

A

yellow fever vaccine(due to high case fatality rate of yellow fever)

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16
Q

which vaccine is contraindicated during lactation

A

yellow fever vaccine

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17
Q

which vaccine can be given during epidemic

A

mesels

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18
Q

vaccine c/i in fever

A

typhoid vaccine

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19
Q

c/i vaccine in hiv positive asymptometic adule

A

no c/i

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20
Q

c/i vaccine in symptomatic hiv positive adult

A

all live vaccins except mmr,vericella,zoster

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21
Q

c/i vaccine in hiv positive newborn

A

all live vaccins except opv,measles

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22
Q

vaccine c/i in epilepsy

A

pertussis

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23
Q

most common vaccine associated with paralysis

A

opv(oral polio vaccine)

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24
Q

most common vaccine associated with hypersenstivity

A

hep b

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25
Q

most common vaccine associated with shock

A

hep b

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26
Q

most common vaccine associated with toxic shock syndrome

A

mesels

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27
Q

most common vaccine associated with GBS

A

killed influnza vaccine

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28
Q

most common vaccine associated with intessusibality

A

rota virus

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29
Q

most common vaccine associated with fever

A

pertussis

30
Q

most common vaccine associated with febrile seizures

A

measles

31
Q

most common vaccine associated with HHE(hypotensive,hyporesponsive,episode0

A

pertussis

32
Q

most common vaccine responsible for persistant inconsolable crying

A

pertussis

33
Q

most common vaccine associated with osteomylitis

A

BCG

34
Q

most common vaccine associated with lymphadinopathy

A

BCG

35
Q

most common vaccine associated with brachial neuritis

A

tetnus toxoid

36
Q

most common vaccine associated with thrombocytopenia

A

mmr

37
Q

lowest level of vaccine storage

A

PHC( primary health center)

38
Q

maximum cold chain failure occour at

A

sub center and below

39
Q

most important component of cold chain in india

A

ILR(ice lined refrigerator)

40
Q

smallest component of cold chain in india

A

ice pack

41
Q

what is reverse cold chain

A

transportation of polio stool sample at 2-8 degree celcius

42
Q

what is warm chain/kangroo mother care

A

used for neonatal hypothermia in low birth weight ,premature newborn
mother uses her body to warm a child

43
Q

what is the reconstituting diluent of BCG vaccine

A

normal saline

44
Q

what is the reconstituting diluent of yellow fever vaccine

A

cold saline

45
Q

what is the reconstituting diluent of MMR,Mesels

A

distil water/sterile water

46
Q

what is the reconstituting diluent of Japanese Encephilitis

A

phosphate buffer saline

47
Q

what is the reconstituting diluent of HIB

A

DPT/Saline

48
Q

BCG vaccine is derived from what strain

A

Danish 1331, which is derived from mycobacterium bovis

and it requires 13 year time

49
Q

OPV vaccine strain

A

p1,p2,p3 (bivalent p1 and p3 strains are used now

50
Q

measles vaccine strains

A

edmonston zagrev
schwarez
moraten

51
Q

mumps vaccine strains

A

jeryll lynn

52
Q

rubella vaccine strain

A

ra27/3

53
Q

yellow fever strain

A

17d

54
Q

varicella strain

A

OKA strain

55
Q

japanese encephilitis strain killed

A

nakayama, beijing p3

56
Q

japanese encephilitis live strain

A

sa 14-14-2

57
Q

h1n1 strain

A

a7 california 2009

58
Q

rabis strain

A

fixed viral strain

59
Q

anthrax strain

A

stern strain

60
Q

typhoral strain

A

ty21 a

61
Q

anti malaria strain

A

spf 66(LYTIC COCKTAIL)

62
Q

mosquirix (malaria vaccine strain)

A

RTS,S

63
Q

anti hiv vaccine strain

A

mva (modified vaccinia ankara strain)

64
Q

what does adjuvant do in DPT vaccine

A

increasing antigenicity

65
Q

role of thiomersal in dpt

A

preservative action

66
Q

role of magnesium chloride in OPV vaccine

A

thermostability agent

67
Q

whhich vaccine has highest effecessy

A

rubella 95%

68
Q

what is new malaria vaccine called and its strain

A

RTS,S (AS01) , mosqurix ,

69
Q

components of mosqurix

A

circumsporozoit protein of plasmodium falciparum +

enveloped protein of the hepatitis b virus+ aduvent AS01

70
Q

strain of dengvaxia

A

cyd-tdv

71
Q

components of dengvaxia

A

replacement of pre membrane and envelop , structural gene of yellow fever attenuated 17 d strain vaccine with 4 dengue serotypes d1,d2,d3,d4

72
Q

age group for dengvaxia

A

9-45 years in endemic areas