Lecture 5: Physiology of Normal White Blood Cells Flashcards
1
Q
bacterial infection leads to an increase in…
A
- neutrophils
- monocytes in chronic infection
2
Q
viral infection leads to an increase in…
A
- lymphocytes
- sometimes monocytes
3
Q
parasite infection leads to an increase in…
A
eosinophils
4
Q
fungal infection leads to an increase in…
A
monocytes
5
Q
allergy leads to an increase in…
A
- basophils
- eosinophils in chronic phase
6
Q
what stimulates monocytes to cross the endothelium and lodge in the intima
A
MCP-1 aka CCL-2
7
Q
what are the types of contact between endothelium and leukocytes
A
initial
- P-selectin and E-selectin on activated endothelium
- recognised by oligosachharides on leucocytes
tighter
- ICAMs on activated endothelium
- recognised by integrins on leukocytes
