IBD Flashcards
What are the differences in presenting features between UC and Crohn’s?
Weight loss and growth failure more common in Crohn’s
Diarrhoea and rectal bleeding more common in UC
What are some extraintestinal features of IBD?
- Erythema nodosum
- Oral changes
- Perianal changes
Which blood investigations are carried out for IBD?
Full blood count & ESR
- Anaemia (mainly Crohn’s)
- Thrombocytosis
- Raised ESR
Which biochemical tests are carried out for IBD?
•Stool calprotectin
- Raised CRP
- Low Albumin (leaking protein into gut, tends to be Crohn’s but sometimes acute severe colitis)
What microbiological tests are carried out to diagnose IBD?
No stool pathogens
What are the differences between IBD presentation in children and adults?
How does incidence of proctitis in child UC patients differ from that of adults?
Typical presentation for adults
How does incidence of left-sided colitis in child UC patients differ from that of adults?
Typical presentation for adults
How does incidence of pancolitis in child UC patients differ from that of adults?
PANCOLITIS -> CHILD!!
How does incidence of isolated ileal inflammation in a child Crohn’s patients differ from that of adults?
How does incidence of illeocolonic inflammation in a child Crohn’s patients differ from that of adults?
Almost even
How does incidence of upper GI/panenteric inflammation in a child Crohn’s patients differ from that of adults?
What are the defintive radiological IBD investiagtions?
(especiallyCrohn’sdisease)
- MRI
- Barium meal and follow-through (younger kids)
What are the definitive endoscopic investigations in IBD?
- Colonoscopy & Upper GI endoscopy
- Mucosal biopsy
- Capsuleenteroscopy
- Enteroscopy
What are the aims of IBD treatments?
- Induce and maintain remission
- Correct nutritional deficiencies
- Maintain normal growth and development
Describe the escalation of IBD treatment?
Azathioprine - immunosuppressant
MP - mercaptopurine
