Lecture 1: Historical Discoveries

Question 1

Aristotle

Answer 1

proposed that the fetus originates from menstrual blood (384-322 BC)

Question 2

Fallopius

Answer 2

discovered and described the oviduct (1562)

Question 3

Coiter

Answer 3

discovered and described the corpus luteum (1573)

Question 4

de Graaf

Answer 4

discovered and described the antral follicle (1672)

Question 5

van Leeuwenhoek

Answer 5

discovered and described spermatozoa in semen (1677)

Question 6

Spallanzani

Answer 6

hypothesized that spermatozoa were the fertilizing agents and successfully artificially inseminated a dog ( 1780)

Question 7

Dumas

Answer 7

proved that spermatozoa were the fertilizing agents (1825)

Question 8

1855 to present

Answer 8

beginning of modern reproductive physiology

• artificial insemination
• biochemical pregnancy detection
• cloning
• contraception
• embryo culture/transfer
• endocrinology
• estrous synchronization
• frozen semen
• in-vitro fertilization
• sex selection in semen and embryos