Integumentary: Wound Healing

Question 1

Types of Tissue Union: Primary

Answer 1

• No major loss of connective tissue
• Wound is not contaminated
• Closure within 3-7 days

Question 2

Types of Tissue Union: Secondary

Answer 2

• Full thickness
• Little Epithelialization
• Chronic Wounds
• Pressure injuries
• Venous Ulcerations

Question 3

Types of Tissue Union: Tertiary

Answer 3

• Contaminated tissue
• Risk of infection
• Closure results in too much tension
• Closed within 5-7 days of initial injury

Question 4

Epidermal

Answer 4

• Heals through regeneration
• Requires a wound border free of necrotic tissue
• Typically heals without scarring
• If dermal tissue involved granulation occurs simultaneously.
• Moist wounds epithelialize faster than those left open to air.

Question 5

Dermal: Phase One: Homeostasis

Answer 5

• Vasoconstriction
• Fibrin plug formation
• Within 10-15 min
• Growth factors released

Question 6

Dermal: Phase Two: Inflammation

Answer 6

• 24-48 hours
• Normal signs of swelling
• Vasodilation
• Leukocytes and growth factors to the area
• Phagosytosis
• Neovascularization
• Immune cells important during this phase

Question 7

Dermis: Phase Three: Granulation/Proliferation/Fibroplastic Phase

Answer 7

• Angiogenisis
• Granulation Formation
• Wound Contraction
• Epithelization
• Myofibroblasts for wound contraction
• Fibroblasts for collagen, elastin, glycosaminoglycan production.

Question 8

Dermis: Phase Four: Maturation

Answer 8

• 2-4 weeks
• Collagen synthesis and alignment
• Normal scar formation
• Hypertrophic and Keloid scar formation
• Compression garments, silicone gels or sheets are used to reduce hypertrophic or keloid scarring.