Anemia classification

Question 1

What is the common underlying defect of all microcytic anemias?

Answer 1

Ineffective hemoglobin production

Question 2

What are the 5 microcytic anemias?

Answer 2

Fe def, ACD (late), thalassemias, lead poisoning, and sideroblastic

Question 3

What are the 2 main categories of normocytic anemias?

Answer 3

hemolytic and non-hemolytic

Question 4

What are the 2 categories of hemolytic anemias?

Answer 4

intrinsic or extrinsic

Question 5

What does “intrinsic” vs. “extrinsic” refer to w/ regard to hemolysis?

Answer 5

intrinsic RBC defect (e.g. spherocytosis, G6PD, sickle cell) or extrinsic force (e.g. autoimmune, angiopathy, infection)

Question 6

What are the 2 categories of macrocytic anemia?

Answer 6

megaloblastic or non-megaloblastic

Question 7

What are the 5 types of non-megaloblastic, macrocytic anemias?

Answer 7

liver disease, alcoholism, reticulocytosis, metabolic disorders, drugs