A: CORONARY ARTERY DISEASE Flashcards

(46 cards)

1
Q

A general term that refers to several diseases other than atherosclerosis

A

Coronary Artery Disease

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2
Q

heart disease with primary manifestations that result from myocardial ischemia owing to atherosclerotic CAD

A

Ischemic Heart Disease

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3
Q

An episodic, reversible oxygen insufficiency, is the most common form of IHD

A

Angina Pectoris

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4
Q

Chest discomfort that are attributable to insufficient myocardial oxygen

A

Angina Pectoris

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5
Q

Types of Angina

A

*Stable (Classic) Angina
*Unstable Angina
*Angina Decubitus
*Prinzmetal Angina

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6
Q

More predictable pattern

A

Stable (Classic) Angina

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7
Q

Stable (Classic) Angina is relieved by

A

Rest or Nitroglycerin

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8
Q

Pain has referred as SQUEEZING, GRIP LIKE SUFFOCATING

A

Stable (Classic) Angina

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9
Q

Lasts for minutes

A

Stable (Classic) Angina

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10
Q

Angina at rest

A

Unstable Angina

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11
Q

Decreased responded to NTG

A

Unstable Angina

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12
Q

Angina Decubitus is also known as

A

Nocturnal angina

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13
Q

Not specifically related to either rest or exertion

A

Angina Decubitus

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14
Q

Gravitational forces shifts fluid within body

A

Angina Decubitus

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15
Q

Angina Decubitus drugs reduce left ventricular volume

A

Diuretics alone or in combination

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16
Q

Angina Decubitus: Nitroglycerin may relieve

A

Paroxysmal nocturnal dyspnea (PND)

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17
Q

Occurs at rest

A

Prinzmetal Angina

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18
Q

What drugs are used for the treatment of Prinzmetal Angina

A

Calcium Channel Blocker and Beta blockers

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19
Q

In this type of Angina, the Nitroglycerin doesn’t provide relief

A

Prinzmetal Angina

20
Q

Bind bile acids within the intestines and prevent from being reabsorbed

A

Bile Acid Binding Resins

21
Q

Drugs of Bile Acid Binding Resins

A
  1. Cholestyramine
  2. Colestipol
  3. Colesevelam
22
Q

Inhibit the enzyme HMG-CoA, resulting in reduction of cholesterol

A

Statins or HMG COA Inhibitor

23
Q

Drugs of Statins or HMG COA Inhibitor

A

*Atorvastatin
*Fluvastatin
*Lovastatin
*Pitavastatin
*Pravastatin
*Rosuvastatin
*Simvastatin

24
Q

Inhibits cholesterol synthesis and lower LDL and bile acids

A

Fibric Acid Derivatives

25
Precautions in Fibric Acid Derivatives
- GI effects - Affects Liver function test
26
Drugs of Fibric Acid Derivatives
Fenofibrate and Gemfibrozil
27
Lowering of LDL and triglycerides
Niacinamide
28
Respiration of oxidation - reduction reactions
Niacinamide
29
Indication of Niacinamide
Elevated total cholesterol and low LDL
30
Special Precautions in Niacinamide
- GI effects - Itchy skin - Cases of severe liver toxicity
31
Inhibits the intestinal absorption of cholesterol and related phytosterols
Ezetimibe
32
Indication of Ezetimibe
- Adjunctive therapy along with dietary measures - Used in combination with STATINS
33
Venous dilation
Nitrates
34
Indication of Nitrates
Acute attacks of angina pectoris
35
Associated with long term use of nitrates
Nitrate Tolerance
36
Reduction of oxygen demand
Beta Blocker
37
Safety Precautions in Beta Blocker
- Should be avoided in Prinzmetal angina - Asthma is a relative contraindication - Hypoglycemia
38
All beta blockers are likely to be equally effective for
Stable angina
39
Reverse coronary spasm by inhibiting calcium influx
Calcium Channel Blockers
40
Decrease coronary vascular resistance
Calcium Channel Blockers
41
Used in stable angina that is not controlled by nitrates and beta blockers and in patients for whom beta blocker therapy is not advisable
Calcium Channel Blockers
42
Drugs of Calcium Channel Blocker
Verapamil Diltiazem Nifedipine
43
Inhibits platelet aggregation induced by adenosine diphosphate
Ticlopidine
44
Just like ticlopidine but produces anti thrombotic effect
Clopidogrel
45
Drugs of Antiplatelet Agents
Aspirin Ticlopidine Clopidogrel
46
Recommended for clinically diagnosed hypertensive agents who are experiencing angina
ACE & ARBs