Abdominal pain Flashcards

(55 cards)

1
Q

What are the three types of abdominal pain based on origin?

A

Visceral: Originates in abdominal organs covered by peritoneum, often crampy (colic).

Parietal: From irritation of parietal peritoneum, typically sharp and localized.

Referred: Produced by pathology in one location but felt at another.

Visceral pain is poorly localized; parietal pain is associated with peritonitis; referred pain examples include shoulder pain from diaphragmatic irritation.

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2
Q

What key history elements should be assessed in the work-up of abdominal pain?

A

Onset

Qualitative description

Intensity

Frequency

Location (including referred pain)

Duration

Aggravating and relieving factors

A thorough history helps differentiate acute vs. chronic and guides diagnostic work-up.

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3
Q

What are the components of the physical examination for abdominal pain?

A

Inspection

Auscultation

Percussion

Palpation

Guarding/rebound tenderness

Rectal exam

Pelvic exam

Guarding and rebound tenderness suggest peritonitis; auscultation assesses bowel sounds.

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4
Q

What laboratory tests are commonly ordered in the work-up of abdominal pain?

A

Urinalysis (U/A)

Complete blood count (CBC)

Additional tests based on rule-outs: amylase, lipase, liver function tests (LFTs)

Elevated WBC may indicate infection; amylase/lipase for pancreatitis.

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5
Q

What diagnostic imaging studies are used for abdominal pain?

A

Plain X-rays (flat plate)

Contrast studies (barium upper/lower GI series)

Ultrasound

CT scanning

Endoscopy

Sigmoidoscopy/colonoscopy

Ultrasound is first-line for gallbladder issues; CT is highly sensitive for acute abdomen.

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6
Q

What conditions are associated with right upper quadrant (RUQ) pain?

A

Acute cholecystitis

Biliary colic

Acute hepatitis or abscess

Hepatomegaly due to CHF

Perforated duodenal ulcer

Myocardial ischemia

Right lower lobe pneumonia

RUQ pain often involves gallbladder or liver pathology; consider referred pain from cardiac/pulmonary causes.

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7
Q

What conditions cause left upper quadrant (LUQ) pain?

A

Acute pancreatitis

Gastric ulcer

Gastritis

Splenic enlargement, rupture, or infarction

Myocardial ischemia

Left lower lobe pneumonia

Pancreatitis typically radiates to the back; splenic issues may present with referred shoulder pain (Kehr’s sign).

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8
Q

What are the causes of right lower quadrant (RLQ) pain?

A

Appendicitis

Regional enteritis (Crohn’s disease)

Small bowel obstruction

Ruptured ectopic pregnancy

Pelvic inflammatory disease (PID)

Twisted ovarian cyst

Ureteral calculi

Hernia

Appendicitis is the most common surgical cause; always rule out ectopic pregnancy in females.

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9
Q

What conditions are associated with left lower quadrant (LLQ) pain?

A

Diverticulitis

Ruptured ectopic pregnancy

Pelvic inflammatory disease (PID)

Twisted ovarian cyst

Ureteral calculi

Hernia

Regional enteritis (Crohn’s disease)

Diverticulitis is common in older adults; LLQ pain in young females requires pregnancy testing.

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10
Q

What causes periumbilical pain?

A

Disease of transverse colon

Gastroenteritis

Small bowel pain

Appendicitis (early)

Early bowel obstruction

Early appendicitis may present with periumbilical pain before localizing to RLQ.

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11
Q

What conditions cause diffuse abdominal pain?

A

Generalized peritonitis

Acute pancreatitis

Sickle cell crisis

Mesenteric thrombosis

Gastroenteritis

Metabolic disturbances

Dissecting or rupturing aneurysm

Intestinal obstruction

Psychogenic illness

Diffuse pain suggests serious conditions like peritonitis or aneurysm; urgent evaluation needed.

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12
Q

What are common causes of referred abdominal pain?

A

Pneumonia (lower lobes)

Inferior myocardial infarction

Pulmonary infarction

Referred pain may mimic abdominal pathology; always consider cardiac/pulmonary causes.

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13
Q

What are common acute abdominal pain syndromes?

A

Appendicitis

Acute diverticulitis

Cholecystitis

Pancreatitis

Perforation of an ulcer

Intestinal obstruction

Ruptured abdominal aortic aneurysm (AAA)

Pelvic disorders

These are surgical emergencies; rapid diagnosis is critical.

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14
Q

What are the classic symptoms of appendicitis?

A

Abdominal pain (starts epigastric/periumbilical, migrates to RLQ)

Anorexia

Nausea or vomiting

Low-grade fever

Pain migration is a hallmark; atypical presentations are common in elderly/children.

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15
Q

What physical exam findings are associated with appendicitis?

A

Low-grade fever

Tenderness at McBurney’s point

Rebound tenderness

Guarding

Positive psoas sign

Rovsing’s sign (palpation of LLQ causes RLQ pain) is high-yield for exams.

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16
Q

What lab and imaging findings support a diagnosis of appendicitis?

A

WBC 10,000–16,000
HCG (to rule out pregnancy)
CT scan (preferred imaging)

CT has high sensitivity/specificity; ultrasound is used in children/pregnant patients.

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17
Q

What is the management for appendicitis?

A

Surgical appendectomy
Antibiotics pre/post-op

Non-perforated cases have excellent outcomes; perforation increases complications.

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18
Q

What are the symptoms of acute diverticulitis?

A

LLQ pain
Low-grade fever
Mild leukocytosis
Minimal abdominal pain

Symptoms may mimic IBS but occur in older patients.

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19
Q

What are the physical exam findings in diverticulitis?

A

Hyperactive bowel sounds (with obstruction)
Tenderness over affected bowel segment

Severe tenderness or guarding suggests perforation/peritonitis.

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20
Q

How is acute diverticulitis managed?

A

Mild cases: Oral antibiotics (e.g., Bactrim DS BID or Cipro 500 mg BID + Flagyl 500 mg TID for 7–14 days), limited activity, reduced fluid intake
Severe cases (peritonitis, sepsis, hypovolemia): Hospital admission, IV antibiotics, NPO

Most mild cases resolve spontaneously; CT confirms diagnosis.

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21
Q

What causes cholecystitis, and what are its symptoms?

A

Cause: Obstruction of cystic/common bile duct by gallstones
Symptoms: Colicky RUQ pain progressing to constant, may radiate to right scapula

Pain is often postprandial, triggered by fatty meals.

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22
Q

What are the physical exam findings in cholecystitis?

A

RUQ tenderness to palpation/percussion
Palpable gallbladder (occasionally)
Positive Murphy’s sign

Murphy’s sign (pain on inspiration during RUQ palpation) is high-yield.

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23
Q

How is cholecystitis diagnosed and managed?

A

Diagnosis: CBC, LFTs (elevated bilirubin, alkaline phosphatase), ultrasound (most accurate)
Management: NPO, IV fluids, analgesics, cholecystectomy ASAP

Ultrasound shows gallstones, gallbladder wall thickening, or pericholecystic fluid.

24
Q

What are the risk factors and symptoms of acute pancreatitis?

A

Risk factors: Cholelithiasis, alcohol abuse
Symptoms: Steady, boring LUQ pain radiating to back, nausea, vomiting, diaphoresis

“GET SMASHED” mnemonic for causes (Gallstones, Ethanol, Trauma, Steroids, Mumps, Autoimmune, Scorpion sting, Hyperlipidemia, ERCP, Drugs).

25
What physical exam and lab findings are seen in acute pancreatitis?
Physical: Acutely ill, abdominal distention, decreased bowel sounds, diffuse rebound tenderness Labs: Elevated amylase (rises 2–12 hours, normalizes in 2–3 days), elevated lipase (elevated for days) ## Footnote Lipase is more specific than amylase.
26
How is acute pancreatitis managed?
Hospital admission NPO IV fluids Analgesics ## Footnote Severe cases may require ICU; complications include pancreatic necrosis, pseudocyst.
27
What are the predisposing factors for peptic ulcer perforation?
Helicobacter pylori infection NSAID use Hypersecretory states (e.g., Zollinger-Ellison syndrome) ## Footnote Perforation is a surgical emergency with high mortality if untreated.
28
What are the symptoms and physical findings of peptic ulcer perforation?
Symptoms: Sudden, severe, steady epigastric pain radiating to sides/back/right shoulder Physical: Epigastric tenderness, rebound tenderness, abdominal muscle rigidity ## Footnote Pain worsens with movement; patients may lie still (peritoneal sign).
29
How is peptic ulcer perforation diagnosed and managed?
Diagnosis: Upright X-ray showing free air under diaphragm Management: Surgical emergency (refer immediately) ## Footnote Free air is seen in 70–80% of cases; CT is more sensitive if X-ray is negative.
30
What causes small bowel obstruction, and what are its symptoms?
Causes: Adhesions, internal hernia Symptoms: Sudden crampy umbilical/epigastric pain, early vomiting (small bowel), late vomiting (large bowel) ## Footnote Adhesions are the most common cause in developed countries.
31
What are the physical exam and diagnostic findings in small bowel obstruction?
Physical: Hyperactive high-pitched bowel sounds, abdominal distention, palpable fecal mass, empty rectum Diagnosis: CBC, serum amylase, stool occult blood, abdominal X-ray (air-fluid levels) ## Footnote X-ray shows dilated loops and air-fluid levels; CT confirms diagnosis.
32
How is small bowel obstruction managed?
Hospitalization NPO IV fluids Nasogastric tube decompression ## Footnote Surgical intervention needed for complete obstruction or strangulation.
33
What is irritable bowel syndrome (IBS), and who is affected?
Functional GI disorder with no structural/biochemical abnormalities Affects 14–24% of females, 5–19% of males Onset: Late adolescence to early adulthood, rare >50 years ## Footnote IBS is a diagnosis of exclusion; rule out organic disease first.
34
What are the Rome diagnostic criteria for IBS?
3+ months of continuous/recurrent symptoms: Abdominal pain/discomfort relieved by bowel movement Associated with change in stool frequency and/or consistency ## Footnote Rome IV criteria are commonly tested; symptoms must be chronic.
35
What additional symptoms support an IBS diagnosis?
Occurring on ≥25% of occasions: Altered stool frequency (>3 BMs/day or <3 BMs/week) Altered stool form (lumpy/hard or loose/watery) Altered stool passage (straining, urgency, incomplete evacuation) Mucus passage Bloating/abdominal distention ## Footnote Mucus and bloating are classic; blood in stool is a red flag for organic disease.
36
What diagnostic tests are used to rule out organic disease in IBS?
CBC with differential ESR Electrolytes BUN, creatinine TSH Stool for occult blood and ova/parasites Flexible sigmoidoscopy ## Footnote Normal tests support IBS; abnormal findings prompt further investigation.
37
How is IBS managed?
Exclude organic disease Provide support/reassurance Dietary modification (e.g., high fiber, avoid triggers) Pharmacotherapy (e.g., antispasmodics, loperamide) Alternative therapies (e.g., CBT, probiotics) ## Footnote Patient education is key; stress management improves outcomes.
38
What is diverticulosis, and who is affected?
Uncomplicated disease (asymptomatic or symptomatic) due to low-fiber Western diets Rare in first 4 decades, incidence 50–65% by age 80 ## Footnote Diverticulosis is often incidental; complications include diverticulitis/bleeding.
39
What are the symptoms of symptomatic diverticulosis?
Irregular defecation Intermittent abdominal pain Bloating Excessive flatulence Flattened/ribbon-like stools Recurrent steady/crampy pain ## Footnote Symptoms mimic IBS but occur in older patients.
40
How is diverticulosis diagnosed and managed?
Diagnosis: CBC, stool for occult blood, barium enema Management: Increase fiber intake to 35 g/day (gradually), avoid popcorn, corn, nuts, seeds ## Footnote High-fiber diet prevents complications; CT is preferred for diverticulitis.
41
What is gastroesophageal reflux disease (GERD), and what are its symptoms?
Movement of gastric contents into esophagus Symptoms: Heartburn (burning midepigastric pain, worsens with recumbency), water brash, postprandial pain relieved by antacids ## Footnote Affects 15% of adults; severe cases may cause dysphagia or chest pain mimicking angina.
42
What are the triggers for GERD symptoms?
High-fat/sugar foods, chocolate, coffee, onions, citrus, tomato-based, spicy foods Cigarette smoking, alcohol Aspirin, NSAIDs, potassium supplements ## Footnote Lifestyle modification is first-line management.
43
How is GERD diagnosed and managed?
Diagnosis: History of heartburn, empiric PPI trial, CBC, H. pylori antibody, barium swallow, endoscopy (for severe/atypical symptoms) Management: Lifestyle changes (smoking cessation, reduce ETOH, elevate head of bed), antacids, sucralfate, PPIs ## Footnote PPIs are most effective; maintenance therapy often required.
44
What are the two types of inflammatory bowel disease (IBD)?
Ulcerative colitis (UC): Continuous inflammation of colonic mucosa, starting in rectum Crohn’s disease: Patchy inflammation of any GI tract segment, often ileum/colon ## Footnote UC is mucosa-limited; Crohn’s is transmural, increasing fistula risk.
45
What are the symptoms of IBD?
Loose/watery stools (may be bloody) Rectal bleeding (common in colitis) Tenesmus, fecal incontinence Fatigue, weight loss, anorexia Fever, chills, nausea, vomiting Joint pains, mouth sores ## Footnote Extraintestinal manifestations (e.g., uveitis, arthritis) are high-yield.
46
How is IBD diagnosed?
CBC, stool for culture/ova/parasites/C. difficile, occult blood. Flexible sigmoidoscopy (for rectal bleeding). Colonoscopy with biopsy (shows skip lesions in Crohn’s). ## Footnote Endoscopy differentiates UC (continuous) from Crohn’s (patchy).
47
How is IBD managed?
Co-managed with GI specialist. 5-aminosalicylic acid (5-ASA) products. Corticosteroids. Immunosuppressives. Surgery (e.g., colectomy for UC, resection for Crohn’s). ## Footnote Biologics (e.g., anti-TNF) are used for refractory cases.
48
What are the risk factors for duodenal ulcers?
H. pylori infection (>90% of cases). NSAID use. Stress, smoking, alcohol, COPD. Genetic factors (e.g., Zollinger-Ellison syndrome, blood group O). ## Footnote H. pylori eradication prevents recurrence.
49
What are the symptoms and management of duodenal ulcers?
Symptoms: Epigastric burning/gnawing pain 1–3 hours after meals, relieved by food/antacids. Management: 2-week antiulcer trial, treat H. pylori, PPIs (superior to H2RAs), misoprostol if NSAIDs continued. ## Footnote Recurrence rate is 75–80% without maintenance.
50
What are the key differences between gastric and duodenal ulcers?
Gastric: H. pylori in 65–75%, pain worsened by food, associated with malignancy, weight loss common. Duodenal: H. pylori in >90%, pain relieved by food, weight gain common, malignancy rare. ## Footnote Endoscopy is required for gastric ulcers to rule out cancer.
51
What is a high-yield clinical pearl for diagnosing appendicitis?
Rovsing’s sign: Palpation of LLQ causes pain in RLQ. ## Footnote Other signs include psoas (hip flexion pain) and obturator (internal rotation pain); highly tested on USMLE.
52
What is Cullen’s sign, and what does it indicate?
Periumbilical bruising indicating hemorrhagic pancreatitis or ruptured ectopic pregnancy. ## Footnote Grey Turner’s sign (flank bruising) is also associated; both are rare but high-yield.
53
What is the most common cause of acute pancreatitis in the US?
Gallstones (40–50% of cases). ## Footnote Alcohol is the second most common cause; hypertriglyceridemia is a key differential.
54
What is a red flag symptom that rules out IBS?
Rectal bleeding or unintentional weight loss. ## Footnote These suggest organic disease (e.g., IBD, cancer); urgent work-up needed.
55
What is the Charcot’s triad for cholangitis?
Fever, jaundice, RUQ pain. ## Footnote Reynolds’ pentad adds hypotension and altered mental status; indicates severe infection.