Abnormal Psych Chapter 6 Flashcards
(105 cards)
Mood disorder
Involves persistent feelings of sadness or periods of feeling overly happy or fluctuations from extreme sadness to extreme happiness
Unipolar depression
Experience only depression
Bipolar disorder
Cycle between periods of depression and periods of mania
Reactive (exogenous) depression
Response to external stressors
Endogenous depression
Arises independent of external stressors
Unipolar depression symptoms
Emotional Symptoms:
*Sadness
*Anhedonia
Physiological/Behavioral Symptoms:
*Sleep disturbances
*Psychomotor retardation
*Fatigue and loss of energy
*Catatonia
Cognitive Symptoms:
*Poor concentration
*Difficulty making decisions
*Feelings of being worthless, hopeless
*Delusions and hallucinations with depressing themes
*Suicidal thoughts
How common is depression?
17% of Americans experience an acute episode at some point in their life
6% experience more chronic depression
What age group has the highest levels of depression? Lowest?
Highest: 15-21
Lowest: 55-70
Gender distribution of depression
Women are about twice as likely as men to experience depressive symptoms
What are the two categories of unipolar depression?
Major Depressive Disorder:
*5 or more symptoms including sadness or loss of interest, lasting at least two weeks
Persistent Depressive Disorder (chronic):
*With major depressive episodes
*With dysthymic syndrome
Manic symptoms of bipolar disorder
Emotional symptoms:
-Elation
-Irritability and agitation
Physiological symptoms:
-More talkative than usual
-Decreased need for sleep
-Increase of activity towards achieving goals
-Impulsive behaviors
Cognitive Symptoms:
-Inflated self-esteem, grandiosity
-Hallucinations
-Racing thoughts
-Distractibility
How common is bipolar disorder?
About 1 in 100 will experience at least one episode of bipolar disorder in their life
Gender distripution of BPD
Men and women seem to be equally likely to develop the disorder
Two categories of bipolar disorder
Bipolar I Disorder:
*elevated mood for at least one week
*plus 3 other symptoms
*depressive episodes can be mild or infrequent
Bipolar II Disorder
*milder episodes of mania (hypomania)
*fit criteria for Major Depression
Large scale brain networks in depression
Increased default mode network activity
Stronger connectivity between nodes of default mode network (long range connectivity)
Stronger connectivity within each node of the default mode network (short range connectivity)
The central executive network has less of an ability to downregulate default mode network
Default mode network
Active when a person is not focused on the outside world and the brain is at wakeful rest, such as during daydreaming and mind-wandering
Bipolar disorder in twins
72% concordance for identical twins, 14% for fraternal twins
Brain abnormalities in depression
Reduced metabolic activity in left prefrontal cortex (goal orientation and motivation), but not right side
Possible over- and under-activity in different emotion centers (e.g. amygdala)
Brain circuit responsible for unipolar depression emerging – prefrontal cortex, hippocampus, amygdala, cingulate cortex
Drug treatments for unipolar depression
Tricyclic Antidepressants e.g. Elavil:
*side effects
*fatal in overdose
*Monoamine Oxidase Inhibitors (MAOIs) e.g. Nardil:
*dietary restrictions to avoid fatal rise in blood pressure from foods containing tyramine
*interactions with drugs, even over-the-counter
*other side effects
Selective Serotonin Reuptake Inhibitors (SSRIs):
*e.g. Prozac, Zoloft, Paxil
Drug treatments for bipolar disorder
Lithium – mood stabilizer
Anticonvulsants
Antipsychotics
Calcium Channel Blockers
Electroconvulsive therapy
Electric current stimulates brief convulsion in temporal lobe of cortex
Used for intractable depression, very rarely for other conditions
Current practice to stimulate only one (usually right) lobe, with lower current and sedation
What are some other biological treatments for depression, other than electroconvulsive therapy?
Repetitive transcranial magnetic stimulation and vagus nerve stimulation, light therapy (for seasonal depression)
Behavioral theories of mood disorders
Reduced Positive Reinforcers:
*Life stress creates a reduction in positive reinforcers leading to withdrawal
Learned Helplessness
Cognitive theories of mood disorders
Beck’s negative cognitive triad theory:
*Negative views of self, world & future
Causal Attributions:
*Internal, stable & global = blame self for negative events
Ruminative Response style