Abx Flashcards

(59 cards)

1
Q

Penicillin target and class

A

cell wall

beta lactam

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2
Q

Methicillin target and class

A

cell wall

beta lactam

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3
Q

Cloxacillin target and class

A

cell wall

beta lactam

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4
Q

Oxacillin target and class

A

cell wall

beta lactam

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5
Q

Ampicillin target and class

A

cell wall

beta lactam

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6
Q

Amoxacillin target and class

A

cell wall

beta lactam

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7
Q

Cephalosporin target and class

A

cell wall

beta lactam cephem

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8
Q

Imipenem target and class

A

cell wall

beta lactam carbapenem

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9
Q

Aztreonam target and class

A

cell wall

beta lactam monobactams

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10
Q

Vancomycin target and class

A

cell wall

non-beta lactam glycopeptide

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11
Q

Bacitracin target and class

A

cell wall

topical

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12
Q

Isonazid target and class

A

cell wall

anti-TB

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13
Q

Rifampin target and class

A

RNA synthesis

rifamycin

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14
Q

Rifabutin target and class

A

RNA synthesis

rifamycin

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15
Q

Lincomycin target and class

A

protein synthesis

lincosamides

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16
Q

Clindamycin target and class

A

protein synthesis

lincosamides

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17
Q

Erythromycin target and class

A

protein synthesis

macrolides

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18
Q

Clarithromycin target and class

A

protein synthesis

macrolides

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19
Q

Azithromycin target and class

A

protein synthesis

macrolides

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20
Q

Streptomycin target and class

A

protein synthesis

aminoglycosides

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21
Q

Gentamycin target and class

A

protein synthesis

aminoglycosides

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22
Q

Tobramycin target and class

A

protein synthesis

aminoglycosides

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23
Q

Quinupristin target and class

A

protein synthesis

streptogramins

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24
Q

Dalfopristin target and class

A

protein synthesis

streptogramins

25
Tigecycline target and class
protein synthesis | glycyclines
26
Tetracycline target and class
protein synthesis | tetracycline
27
Doxycycline target and class
protein synthesis | tetracycline
28
Minocycline target and class
protein synthesis | tetracycline
29
Zyvoz target and class
protein synthesis | oxazolidinone
30
Sivextro target and class
protein synthesis | oxazolidinone
31
Nystatin target and class
cell membrane | polyvene
32
Amphotericin target and class
cell membrane | polyvene
33
Chlorhexidine target and class
cell membrane | antispetic mouthwash
34
Polymyxin target and class
cell membrane | topical
35
Daptomycin target and class
cell membrane | lipopeptide
36
Metronidazole target and class
DNA synthesis | nitroimidazole
37
Ciproflaxocin target and class
DNA synthesis quinolones fluoroquinolones
38
Sulfadiazine target and class
metabolism | sulfonamides
39
Trimethoprim target and class
metabolism | sulfonamides
40
Beta lactam MOA
interferes with cross linking of peptidoglycan
41
Non-beta lactam glycopeptide MOA
cell wall synthesis inhibitor
42
Bacitracin MOA
stops cell wall synthesis
43
Isoniazid MOA
inhibits mycolic acid synthesis
44
Rifamycin MOA
inhibits transcription initiation
45
Lincosamides MOA
translation inhibitor, blocks 50S ribosome, and inhibits translocation
46
Macrolides MOA
translation inhibitor binds 50S ribosome
47
Aminoglycosides MOA
translation inhibitor blocks 30S ribosome
48
Macrocyclics MOA
RNA polymerase inhibitor in C. diff only
49
Streptogramins MOA
binds 50S ribosome
50
Glycocyclines MOA
block 30S ribosome
51
Tetracyclines MOA
translation inhibitor, blocks 30S ribosome, stops tRNA binding
52
Oxazolidinone MOA
block tRNA binding to ribosome
53
Polyvene MOA
binds ergosterol in fungal cell membrane
54
Chlorhexidine MOA
membrane disruption
55
Polymyxin MOA
detergent action
56
Lipopeptide MOA
disrupts ionic concentration gradients
57
Nitroimidazole MOA
strict anaerobes are sensitive and some protozoa
58
Quinolone and fluoroquinolone MOA
inhibit DNA gyrase- transcription inhibitor
59
Sulfonamides MOA
blocks folic acid synthesis- need folate for DNA