ABX stuff Flashcards
(23 cards)
MIC
does required to stop growth (static)
MBC
does required to kill 99% of bacteria (cidal)
Post-antibiotic effect
and an example?
drug has short half but continues kllling bacteria even if systemic concentration drops below MIC/MBC
eg. AGs!
Bacillus anthracis
Aerobic GP Rod
Anthrax
FQ, doxy, Pen G + streptomycin
Corynebacterium diptheria
Aerobic GP Rod
Diptheria
Pen G, Macrolides
Listeria
Aerobic GP Rod
Bacteremia, meningocephalitis
AMP +/- gentamycin
Neisseria meningitidis
Aerobic GN diplococci
Meningitis
Pen G, cefuroxime (2nd gen)
Neisseria gonorrhea
Aerobic GN diplococci
Gonorrhea, conjunctivits
Ceftriaxone (3rd) + azithro (MAC), doxy (TCN)
M. catarrhalis
Aerobic GN diplococci
Otitis media, CA-PNA
Amoxi-clav (BLase inhib), 2nd/3rd cephs, MAC, FQ
Clostridium (tetani, botulinum, perfrigens)
Anaerobic GP Rod (strict killed by O2)
Tet, Bot, perf : gangrene and food poisoning
Pen G, Metro, Clinda
Clostridum Difficile
Anaerobic GP Rod
Pseudomebranosus colitis
Metro, Vanco po, fidaxomicin
Propionibacterium acnes
Anaerobic GP Rod
Acne
TCN, clinda (topical), eryhtro (topical)
H pylori
Anaerobic GN Rod
Peptic ulcer dz
Amox, MAC, TCN, metro
Bacterioides (B. fragilis, B melaninogenicus)
Anaerobic GNR
Intrabdominal brain abscesses
METRO, clinda, 2nd cephs, carbapenems PLUS anti-pseudomonal pens (PIP, TICAR)
Mycobacterium tuberculosis
No cell wall
Tuberculosis
Rifampin, Isoniazid, Streptomycin (Ethambutol, Pyrazinamide)
M. avium intracellulare
No cell wall
PNA
MAC, Rifabutin
Mycoplasma pneumoniae
No cell wall
CA-PNA
MAC, TCN
Treponema pallidum
Spirochetes
Syphilis
Pen G, MAC, Ceftriaxone, TCN
Leptospira and Borrelia
Spirochetes
Pseudomonas aeruginosa
GNR (opportunistic)
PNA/Lung infx in CF patients, Infx, UTI
PIP/TICAR (anti-pseudomonal PENS)
Bordetella pertussis
GNR
pertussis/whooping cough
MACs
Chlamydia (all types)
Obligate intracellular
TCN, MAC
Rickettsia
Obligate intracellular
Rocky Mountain Spotted Fever, Q fever
Doxy, chlor
