Acid-Base Flashcards

(51 cards)

1
Q

What causes an increase in acid production?

A
  • Excessive oxidation of fatty acids
  • Hypermetabolism
  • Excessive ingestion of ethanol and salicylate
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2
Q

What causes excessive oxidation of fatty acids?

A
  • Starvation
  • Ketoacidosis
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3
Q

What causes hyper metabolism?

A
  • Exercise
  • Seizures
  • Fever
  • Ischemia
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4
Q

What causes an increase in acid loss?

A
  • Vomiting
  • Gastric suctioning
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5
Q

What causes a decrease in acid excretion?

A
  • Renal failure
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6
Q

What causes bicarbonate loss or underproduction?

A
  • Diarrhea
  • Excessive ileostomy drainage
  • Pancreatitis
  • Liver failure
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7
Q

What causes an increase in bicarbonate?

A
  • Alkaline ingestion
  • Excessive sodium bicarbonate administration
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8
Q

What causes increased/decreased levels of CO2?

A
  • Respiratory conditions
  • Opiate overdose
  • Anxiety
  • Fever
  • COPD
  • Inadequate chest expansion
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9
Q

Normal pH levels

A

7.35 - 7.45

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10
Q

Normal PaCO2

A

35 - 45 mmHg

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11
Q

Acidotic PaCO2

A

<35 mmHg

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12
Q

Alkalotic PaCO2

A

> 45 mmHg

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13
Q

Normal HCO3

A

22 - 28 mEq/L

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14
Q

Acidotic HCO3

A

<22 mEq/L

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15
Q

Alkalotic HCO3

A

> 28 mEq/L

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16
Q

Normal PaO2

A

80 -100 mmHg

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17
Q

Normal SaO2

A

> 95%

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18
Q

Respiratory acidosis

A
  • Increased CO2
  • Decreased pH
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19
Q

Causes of respiratory acidosis

A
  • Hypoventilation
  • Decreased respiratory drive/respiratory depression
  • Neuromuscular disorders
  • Airway obstruction/alveolar capillary exchange
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20
Q

Respiratory alkalosis

A
  • Increased pH
  • Decreased PaCO2
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21
Q

Metabolic alkalosis

A
  • Increased pH
  • Increased HCO3
22
Q
  • Causes of metabolic alkalosis
A
  • Loss of gastric acid
  • Loss of K+
  • Cushing’s syndrome
  • Ingestion of excess antacids, baking soda
  • IV administration of bases
23
Q

Examples of loss of gastric acid

A
  • Severe vomiting
  • Nasogastric suctioning
  • Gastric fistulas
24
Q

Examples of K+ loss

A
  • Excessive diuretic therapy
25
Examples of IV administration of bases
- Sodium bicarbonate - TPN - Lactate in Ringer's lactate - Citrate in massive amounts of blood transfusions
26
Metabolic alkalosis vitals
- Tachycardia - Normal - hypotensive BP
27
Metabolic alkalosis respiratory s/s
- Hypoventilation
28
Metabolic alkalosis near s/s
- Irritable - Lethargic - Confused - Headache
29
Metabolic alkalosis neuromuscular s/s
- Tetany - Tremors - Numbness/tingling in fingers/toes - Muscle cramps - Hyperactive reflexes - Seizures
30
Metabolic alkalosis cardiac s/s
- dysrhythmias r/t hypokalemia
31
Electrolyte problems associated with metabolic alkalosis
- Hypokalemia - Hypochloremia - Hypocalcemia
32
Metabolic acidosis causes
- DKA - Starvation - Alcoholism - Rhabdomyolysis - Ingestion of aspirin/salicylates - Chronic renal failure - Severe lung problems - Prolonged diarrhea - Pancreatitis
33
Metabolic acidosis vitals
- Bradycardia - Hypotension - Tachypnea
34
Metabolic acidosis cardiac s/s
- Dysrhythmias - Possible cardiac arrest
35
Metabolic acidosis respiratory s/s
- Kussmaul respirations - Deep, rapid respirations
36
Metabolic acidosis neuro s/s
- Lethargic - Confused - Dizziness - Headache - Decreased LOC, stupor, coma
37
Metabolic acidosis GI s/s
- N/V/D - Abdominal pain
38
Metabolic acidosis neuromuscular s/s
- Muscle Weakness
39
Metabolic acidosis skin s/s
- Cold - Clammy
40
Normal anion gap
8 - 12 mol/L
41
DKA labs
- Hyperglycemia >250 - AGAP open >12 - Metabolic acidosis - Serum HCO3 <18 - Electrolyte imbalances
42
DKA triggers
- Infections - Pregnancy - Insufficient/missed insulin - Trauma/emotional stress/surgery - MI - Exercise - Alcohol abuse - Medications
43
What infections are common triggers for DKA?
- PNA - UTI - Sepsis - Pancreatitis
44
What medications are common triggers for DKA?
- Corticosteroids - Thiazide diuretics - Atypical antipsychotics
45
DKA s/s
- Polydipsia - Polyuria - Polyphagia - N/V - Blurred vision - Weakness/lethargy - Fruity/rotting fruit breath - Kussmaul respirations
46
DKA vital signs
- Tachycardia - Hypotension - Tachypnea
47
DKA neuro s/s
- Change in mental status - Malaise - Lethargy
48
DKA integumentary s/s
- Warm - Dry - Flushed
49
DKA GI s/s
- N/V - Weight loss - Increased thirst - Fruity breath
50
DKA GU s/s
- Increased urination - Significant dehydration
51
DKA