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Flashcards in acid base imbalane Deck (20):
1

why is normal pH critical to survival?

enzymes are protens which ar sensitive to pH as it will easily damage them by denaturing. Enxymes must retain their shape *lock and key* in order to catalyze reactions. Enxymes are very important for bodily fx

2

how is ph measured clinically

arterial blood gas lab values

3

what information does a ph measured clinically give? how would this be obtained

gases, ph- this shows respiratory function and metabolic function
taken from venous blood

4

ph is a measure of?

hydrogen ion concentration

5

low ph=
high ph=

0-7=acidic
high=7-14 basic

6

alkalosis=

ph >7.45

7

acidosis=

ph

8

what are the 4 types of acid base imbalances

metabolic acidosis and alkalosis
respiraotry acidosis and alkalosis

9

how does the body address an acid base imbalance?

buffering.

10

how can metabolic be distinguihed from respiratory

if there is involvement of carbonic acid (h2c03)

11

how do you measure H2C03?

you cant really as it is too volatile. They measure the amount of C02 by PC02

12

what is PCO2

partial pressure of \C02

13

is it the amoun of HC03- or dissolved H2C03=H+HC03-)that determines ph?

no, it is the ratio of them
when the ratio is 20 HC03 to 1 C02 it can remain normal

14

carbonic acid-bicarbonate buffer system

C02 + H20=H2\C03=H+ + HC03-
(principal buffer system in ECF)
carbonic acid is transported in the body as carbaminohemoglobin, a dissolved gas, and as bicrabonate.

15

volatile acids in the body are eliminated by

the lungs (h2C03)

16

how do respiratory imbalances work

a C02 elimination problem. eg asthma, COPD, lung cancer
-impaird ventilation leads to inc Pc02 leads to dec pH this is resp acidosis
-excess elimination of C02 leads to dec PC02 leads to inc in pH and respirator

17

how does metabolic imbalance work

due to high inc or dec in acid or base
metabolic acidosis can be due to inc acid or dec base
metabolic alkalosis can be due to inc base or dec in H+ ions

18

how does the body compensate for acid base imalances

kidney and lung compensate for each other an this normalizes pH

19

how can nurses treat acid base imbalances

oral and IV solution to normalize pH (which doesnt fix underlying cause)
or address underlying cause

20

formula for carbonic acid-bicarbonate buffer

C02+H20=(catalyzed by carbonic anhydrase)=H2C03=+HC03-