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Phamacology Summer > Acid Controlling Drugs > Flashcards

Acid Controlling Drugs Flashcards

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1
Q

Antacids

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
b. cimetidine
c. ranitidine
d. omeprazole
e. Sucralfate (Carafate)
f. Misoprostol
h. Simethicone ▪Bismuth
i. subsalicylate

A

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

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2
Q 
H2RA's (Histamine2 Receptor
Antagonists)
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
b. cimetidine 
c. ranitidine
d. omeprazole
e. Sucralfate (Carafate) 
f. Misoprostol
h. Simethicone ▪Bismuth 
i. subsalicylate
A

b. cimetidine

c. ranitidine

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3
Q

Proton Pump Inhibitors

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
b. cimetidine
c. ranitidine
d. omeprazole
e. Sucralfate (Carafate)
f. Misoprostol
h. Simethicone ▪Bismuth
i. subsalicylate

A

d. omeprazole

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4
Q

◦ Anti-Ulcer Agents

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
b. cimetidine
c. ranitidine
d. omeprazole
e. Sucralfate (Carafate)
f. Misoprostol
h. Simethicone ▪Bismuth
i. subsalicylate

A

e. Sucralfate (Carafate)

f. Misoprostol

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5
Q

REMEMBER- NSAIDS, Anticoagulants, Anti-platelets are contra- indicated in PUD! Alcohol, Smoking, Steroids!

A

ok

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6
Q

Antacids are usually NOT administered simultaneously with other medications, or even within ? hours of other medications

A

Antacids are usually NOT administered simultaneously with other medications, or even within 1-2 hours of other medications

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7
Q

Many antacid combinations include simethicone. Know simethicone (Gas-X). This reduces surface tension of gas bubbles

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
b. cimetidine
c. ranitidine
d. omeprazole
e. Sucralfate (Carafate)
f. Misoprostol
h. Simethicone ▪Bismuth
i. subsalicylate

A

Simethicone

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8
Q

? believed help bind growth factors to injured mucosa

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

Aluminum

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9
Q

◦ Can be used in CKD to treat hyperphosphatemia

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

Aluminum

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10
Q

Commonly cause diarrhea

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

Magnesium Hydroxide

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11
Q

CONTRA-INDICATION: Dangerous when used with renal failure; the failing kidney cannot excrete extra magnesium, resulting in accumulation

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

Magnesium Hydroxide

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12
Q

May cause:
◦ Constipation
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

calcium carbonate (Tums), Aluminum

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13
Q

May cause:
◦ Kidney stones
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

calcium

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14
Q

May cause:
◦ Milk Alkali Syndrome (don’t give with milk!)
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

calcium

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15
Q

May cause:
◦ Rebound Hypersecretion of Acid
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide

A

calcium

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16
Q

UNIQUE PROFILE
◦ Long duration of acid action—may cause increased gastric acid secretion (hyperacidity rebound)
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

A

calcium

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17
Q

? content may cause problems in patients with heart failure (HF), hypertension, or renal insufficiency.
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

A

Sodium Bicarbonate

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18
Q

◦ May cause metabolic alkalosis
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

A

Sodium Bicarbonate

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19
Q

Highly soluble
◦ Buffers the acidic properties of HCl
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

A

Sodium Bicarbonate

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20
Q

◦ Quick onset but short duration
a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

A

Sodium Bicarbonate

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21
Q

Constipation:

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

A

Aluminum/Calcium

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22
Q

Diarrhea:

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

A

Magnesium

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23
Q

Kidneys: Avoid

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

24
Q

Heart Failure: Avoid any that have

a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide
Sodium Bicarbonate

Study These Flashcards
A

SODIUM (Sodium Bicarb)

25
? is given for CKD (hyperphosphatemia) a. calcium carbonate (Tums), Aluminum Hydroxide, Magnesium Hydroxide Sodium Bicarbonate
Aluminum
26
``` USED TO TREAT: ▪Gas Pain b. cimetidine c. ranitidine d. omeprazole e. Sucralfate (Carafate) f. Misoprostol h. Simethicone ▪Bismuth i. subsalicylate ```
Simethicone
27
Anti-Androgen b. cimetidine c. ranitidine
b. cimetidine
28
▪ Liver Enzyme Inhibition b. cimetidine c. ranitidine
b. cimetidine
29
▪ Cleaned up version (no androgen/liver issues) b. cimetidine c. ranitidine
c. ranitidine
30
ADVERSE EFFECTS: ▪Can accumulate in renal impairment b. cimetidine c. ranitidine
Both
31
▪Change pH in the gut b. cimetidine c. ranitidine
Both
32
KIDNEY DISEASE/GERIATRICS: b. cimetidine c. ranitidine
Both
33
PH CHANGE IN GI TRACT: b. cimetidine c. ranitidine
Both
34
educate patients to notify prescriber of foul smelling/greenish diarrhea b. cimetidine c. ranitidine
Both
35
ANTI-ANDROGEN: may induce impotence and gynecomastia. b. cimetidine c. ranitidine
b. cimetidine
36
ENZYME INHIBITOR interacts with many drugs- caution with other drugs b. cimetidine c. ranitidine
b. cimetidine
37
Thrombocytopenia and Hepatotoxicity b. cimetidine c. ranitidine
c. ranitidine
38
Administration- H2RAs and antacids should be administered at least ? hours apart
Administration- H2RAs and antacids should be administered at least 1-2 hours apart
39
``` USED TO TREAT: Stress Ulcer Prophylaxis (SUP) d. omeprazole e. Sucralfate (Carafate) f. Misoprostol h. Simethicone ▪Bismuth i. subsalicylate ```
d. omeprazole
40
``` ADVERSE EFFECTS ◦ diarrhea ◦ Change in gut pH d. omeprazole e. Sucralfate (Carafate) f. Misoprostol h. Simethicone ▪Bismuth i. subsalicylate ```
d. omeprazole
41
``` Change in absorption of electrolytes ▪long term –hypomagnesemia ▪Long term- hypocalcemia ◦ Fractures and Osteoporosis (due to hypocalcemia) d. omeprazole e. Sucralfate (Carafate) f. Misoprostol h. Simethicone ▪Bismuth i. subsalicylate ```
d. omeprazole
42
Monitor for long term treatment complications: ▪Osteoporosis (Vitamin D + Calcium intake) ▪Pneumonia/C.Diff (patients monitor S/S) d. omeprazole e. Sucralfate (Carafate) f. Misoprostol h. Simethicone ▪Bismuth i. subsalicylate
d. omeprazole
43
omeprazole ADMINISTRATION: ◦ Patients should take first thing in the morning, ? minutes before their first meal
ADMINISTRATION: | ◦ Patients should take first thing in the morning, 30 minutes before their first meal
44
“BAND AID BARRIER” e. Sucralfate (Carafate) f. Misoprostol h. Simethicone ▪Bismuth i. subsalicylate
e. Sucralfate (Carafate)
45
▪May bind other drugs e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate
e. Sucralfate (Carafate)
46
Sucralfate | Separate administration of other drugs ? hours before/after)
Separate administration of other drugs (2 hours before/after)
47
``` USED TO TREAT: ▪Diarrhea (traveler’s diarrhea) ▪ Indigestion/Heartburn e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate ```
i. Bismuth subsalicylate
48
component has bactericidal properties e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate
i. Bismuth
49
component may act as anti-inflammatory e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate
subsalicylate
50
``` ADVERSE EFFECTS: ▪May stain tongue, bowel movements green/black e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate ```
i. Bismuth subsalicylate
51
``` USED TO TREAT Promotes Cervical Ripening (Labor Induction) e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate ```
f. Misoprostol
52
``` USED TO TREAT Treat Postpartum Hemorrhage e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate ```
f. Misoprostol
53
``` USED TO TREAT Can be used for termination of Pregnancy (we will discuss more in L&D section) e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate ```
f. Misoprostol
54
``` MECHANISM OF ACTION: Prostaglandin analog- suppress stomach acid e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate ```
f. Misoprostol
55
Pregnancy Category X e. Sucralfate (Carafate) f. Misoprostol h. Simethicone i. Bismuth subsalicylate
f. Misoprostol

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