ACS highlights Flashcards
(16 cards)
Describe ACS age risk if Significant + FHx of CAD
Male < 55 y/o
Female < 65 y/o
Marburg Heart score can assess likelihood of cardiac origin of intermittent CP in _______________ setting
outpatient
List 2 clinical decision tools to estimate cardiac risk and mortality in ER or inpatients
HEART score and Thrombolysis in MI risk score
True or false: There’s no validated clinical tool to R/O ACS in outpatient setting
True
List categories of DDxs for chest pain
1) Cardiovascular < 20-30%
2) Pulmonary 5%
3) Psychiatric
4) MSK 33-50%
5) GI 10-20%
all patients with possible cardiac chest pain should get what?
EKG
High sensitivity cardiac ___________ can help diagnose ACS
troponins
What is needed to DX MI?
Elevated cardiac enzymes AND at least one of the following:
1) Ischemic symptoms
2) ECG changes (like new ischemic changes; Q waves)
3) Imaging evidence of new myocardial loss or wall motion abnormality in pattern consistent with ischemic etiology (echo or nuclear scan)
3) ID coronary thrombus on angiography
Give one example of a non-ischemic causes of elevated cardiac enzymes
Chronic and Acute renal disease
List 2 DES meds for Dual antiplatelet therapy for stents
Clopidogrel (Plavix) 75 mg qd
Ticagrelor (Ticlid) 90 mg bid
______ inhibitionofplateletfunction by acetylation of plateletcyclooxygenase (COX) at the functionally important amino acid serine529
ASA
_______________________ inhibitplatelet aggregationby irreversibly blocking the adenosine diphosphateP2Y12receptor
P2Y12 inhibitors (“grels”)
NSAIDs directly target ________________________, reducing inflammationandpain.
cycloxygenase-2,COX-2
1) NSAIDs reduces the risk of_______________, perhaps renal function
2) Give 2 examples
1) peptic ulceration
2) celecoxib, meloxicam at 7.5 mg dosing
Cox-2i and Cox-1i (traditional NSAID) received_______________on their labels regarding cardiovascular risks
boxed warnings
List 2 f/u tests after ACS
1) Echo to eval LV funct
2) Stress test
