Actinic keratosis

Question 1

Erythematous nodule with central ulceration and crust, firm with palpation what type of lesion?

Answer 1

R/o squamous cell carcinome with shave biopsy

Question 2

Which carcinoma is associated with increased mortality?

Answer 2

SCC c/w BCC due to mets

Question 3

Cell of origin of SCC?

Answer 3

Keratinocyte

Question 4

Etiology of SCC

Answer 4

• cumulative UV exposure

- can arise in non-exposed areas

Question 5

what 3 non-sun related risk factors exist for SCC

Answer 5

arsenic exposure
HPV exposure if genital respiratory
smoking, tobacco use if oral

Question 6

sCC in situ is also known as

Answer 6

Bowen’s disease

Question 7

circumcised pink to red patch or thin plaque with scaly or rough surface

Answer 7

Bowen’s disease

Question 8

the treatment of choice for SCCs is

Answer 8

surgical removal and mohs

Question 9

In situ SCC can be treated with

Answer 9

curette and dessication

Question 10

Non surgical treatment options for SCC

Answer 10

radiation therapy, 5-FU, imiquimod,

Question 11

rough scaly, thin red-pink papules scattered on forehead and temple

Answer 11

Actinic keratosis (can transform to SCC)

Question 12

risk of malignant transformation for AK to SCC

Answer 12

1 in 100

Question 13

cell of origin for AK

Answer 13

keratinocyte

Question 14

AKs on the lips is called

Answer 14

Actinic cheilitis

Question 15

field therapies to treat AKs

Answer 15

5FU, imiquimod, photodynamic therapy

Question 16

broad spectrum sunscreen protects against

Answer 16

UVA and UVB

Question 17

Educate the patient with AKs to

Answer 17

protect, every 2 hours apply sunscreen
seek shade,
wear protective clothing