Acute & Emergency

Question 1

what is erythroderma?

Answer 1

?inflammatory skin disease affecting >90% of the total skin

Question 2

Stevens Johnson Syndrome symptoms?

Answer 2

fever 
malaise
arthralgia
rash
mouth ulceration (plus mucous membranes)

Question 3

what is the ScorTen criteria?

Answer 3

age >40
malignancy
HR >120
serum glucose >14
serum bicarbonate <20

Question 4

what is erythema multiforme?

Answer 4

hypersensitivity reaction usually triggered by infection (HSV)

Question 5

what happens in erythema multiforme?

Answer 5

abrupt onset of up to 100s of lesions over 24 hours

• distal to proximal
• palms & soles

Question 6

erythema multiforme course?

Answer 6

self-limiting and resolves over 2 weeks

Question 7

what is DRESS?

Answer 7

drug reaction with eosinophilia and systemic symptoms (DRESS)

Question 8

timing in DRESS?

Answer 8

onset is 2-8 weeks after drug exposure

Question 9

symptoms in DRESS?

Answer 9

fever and widespread rash
eosinophilia and deranged LFTs
Lymphadenopathy

Question 10

what is the symptom of Pemphigus?

Answer 10

superficial blistering that are flaccid and rupture very easily

Question 11

what happens in Pemphigus?

Answer 11

antibody targeted at desmosomes